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Total 8 results found since Jan 2013.

Cardiovascular Programming During and After Diabetic Pregnancy: Role of Placental Dysfunction and IUGR
This study demonstrated that the incidence of ischemic heart disease and death were three times higher among men with low birth weight compared to men with high birth weight (5). Epidemiological investigations of adults born at the time of the Dutch famine between 1944 and 1945 revealed an association between maternal starvation and a low infant birth weight with a high incidence of hypertension and coronary heart disease in these adults (23). Furthermore, Painter et al. reported the incidence of early onset coronary heart disease among persons conceived during the Dutch famine (24). In that regard, Barker's findin...
Source: Frontiers in Endocrinology - April 8, 2019 Category: Endocrinology Source Type: research

Endocrine Disruptors and Health Effects in Africa: A Call for Action
Conclusion: To address the many challenges posed by EDCs, we argue that Africans should take the lead in prioritization and evaluation of environmental hazards, including EDCs. We recommend the institution of education and training programs for chemical users, adoption of the precautionary principle, establishment of biomonitoring programs, and funding of community-based epidemiology and wildlife research programs led and funded by African institutes and private companies. https://doi.org/10.1289/EHP1774 Received: 16 February 2017 Revised: 22 May 2017 Accepted: 24 May 2017 Published: 22 August 2017 Address correspond...
Source: EHP Research - August 23, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Commentary Source Type: research

Adolescent bariatric surgery is on the Rise: An analysis of utilization and procedure trends in New York State
Obesity constitutes a major public health issue affecting an increasing number of families. In the United States the percentage of adolescents aged 12-19 years with obesity has reached an alarming level of 21%.  Childhood obesity could lead to long term development of heart disease, type 2 diabetes, stroke, several types of cancer, and osteoarthritis. The bariatric surgical interventions have emerged as successful alternative to the behavioral and psychological interventions in weight loss for adolescents .
Source: Surgery for Obesity and Related Diseases - October 1, 2017 Category: Surgery Authors: Shabana Humayon, Maria Altieri, Jie Yang, Kristie Price, Konstantinos Spaniolas, Aurora Pryor Tags: Bariatric Surgery in Adolescents Source Type: research

Metabolism and Memory: Obesity, Diabetes, and Dementia
When Michelle Obama launched her Let ’s Move! campaign against childhood obesity in 2010, it came on the heels of data showing that 36% of U.S. adults and 17% of U.S children and adolescents were obese (1). The associated health risks outlined by Ms. Obama’s team reflected the Centers for Disease Control and Prevention’s consensu s, which emphasized a myriad of adverse outcomes ranging from cancer to arthritis to coronary artery disease. Among these public health messages, the neuropsychiatric consequences of obesity have narrowly focused on cerebrovascular disease, such as stroke, and the psychological consequences of stigm a.
Source: Biological Psychiatry - October 28, 2017 Category: Psychiatry Authors: Daniel Shalev, Melissa R. Arbuckle Tags: Clinical Commentary Source Type: research

Sex Difference of Radiation Response in Occupational and Accidental Exposure
Conclusion and Outlook This review summarizes the data from major human studies on the health risks of radiation exposure and shows that sex can potentially influence the prolonged response to radiation exposure (Figure 1 and Tables 1, 2). These data suggest that long-term radiosensitivity in females is higher than that in males who receive a comparable dose of radiation. Our analysis of the literature agrees with the conclusions of the recent report on the Biological effects of ionizing radiation (BEIR VII) published in 2006 by the National Academy of Sciences (NAS), United States (National Research Council, 2006). The B...
Source: Frontiers in Genetics - May 2, 2019 Category: Genetics & Stem Cells Source Type: research

How to Keep Alzheimer ’s From Bringing About the Zombie Apocalypse
I tried to kill my father for years. To be fair, I was following his wishes. He’d made it clear that when he no longer recognized me, when he could no longer talk, when the nurses started treating him like a toddler, he didn’t want to live any longer. My father was 58 years old when he was diagnosed with Alzheimer’s disease. He took the diagnosis with the self-deprecating humor he’d spent a lifetime cultivating, constantly cracking jokes about how he would one day turn into a zombie, a walking corpse. We had a good 10 years with him after the diagnosis. Eventually, his jokes came true. Seven years ...
Source: TIME: Health - November 20, 2019 Category: Consumer Health News Authors: Jay Newton-Small Tags: Uncategorized Alzheimer's Disease Source Type: news

Drugs against alpha-ketoglutarate may combat deadly childhood brain tumor
(NIH/National Institute of Neurological Disorders and Stroke) Every year, 150 to 300 children in the United States are diagnosed with diffuse intrinsic pontine gliomas (DIPGs), aggressive and lethal tumors that grow deep inside the brain, for which there are no cures. In a study funded by the National Institutes of Health, researchers showed that experimental drugs designed to lower the body's natural production of alpha-ketoglutarate extended the lives of mice harboring DIPG tumors by slowing the growth of the cancer cells.
Source: EurekAlert! - Cancer - August 18, 2020 Category: Cancer & Oncology Source Type: news