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Total 854 results found since Jan 2013.

The Difficulty Of Counting the COVID-19 Pandemic ’s Full Death Toll
Sara Wittner had seemingly gotten her life back under control. After a December relapse in her battle with drug addiction, the 32-year-old completed a 30-day detox program and started taking a monthly injection to block her cravings for opioids. She was engaged to be married, working for a local health advocacy group in Colorado, and counseling others about drug addiction. Then the COVID-19 pandemic hit. The virus knocked down all the supports she had carefully built around her: no more in-person Narcotics Anonymous meetings, no talks over coffee with trusted friends or her addiction recovery sponsor. As the virus stressed...
Source: TIME: Health - June 22, 2020 Category: Consumer Health News Authors: Markian Hawryluk / Kaiser Health News Tags: Uncategorized COVID-19 Source Type: news

Expansion of the dimensions in the current management of acute ischemic stroke
AbstractStroke is the fifth leading cause of death in the United States with a huge burden on health care. Acute ischemic stroke (AIS) accounts for 87% of all stroke. The use of thrombolytic agents in AIS treatment is well known since 1950 but no FDA approval until 1996, due to lack of strong evidence showing benefits outweigh the risk of intracranial hemorrhage. The NINDS trial led to the approval of intravenous tissue plasminogen activator treatment (IV recombinant tPA) within 3  h of stroke. Due to this limitation of 3–4.5 h. window, evolution began in the development of effective endovascular therapy (EVT). Multipl...
Source: Journal of Neurology - May 19, 2020 Category: Neurology Source Type: research

Coronavirus concerns keep heart patients from hospital: 'I was so scared'
Hospitals across the United States are seeing fewer stroke and heart patients coming to their facilities for care -- and two new papers tie that trend to the coronavirus pandemic.
Source: CNN.com - Health - May 13, 2020 Category: Consumer Health News Source Type: news

Fluid Response Evaluation in Sepsis Hypotension and Shock: A Randomized Clinical Trial.
Abstract BACKGROUND: Fluid and vasopressor management in septic shock remains controversial. In this randomized controlled trial, we evaluated the efficacy of dynamic measures (stroke volume change during passive leg raise) to guide resuscitation and improve patient outcome. RESEARCH QUESTION: Will resuscitation guided by dynamic assessments of fluid responsiveness in patients with septic shock improve patient outcomes? STUDY DESIGN: and Methods: Prospective, multicenter, randomized clinical trial at 13 hospitals in the United States and United Kingdom. Patients presented to Emergency Rooms with sepsis a...
Source: Chest - April 26, 2020 Category: Respiratory Medicine Authors: Douglas IS, Alapat PM, Corl KA, Exline MC, Forni LG, Holder AL, Kaufman DA, Khan A, Levy MM, Martin GS, Sahatjian JA, Seeley E, Self WH, Weingarten JA, Williams M, Hansell DM Tags: Chest Source Type: research

Amid the Coronavirus Crisis, Heart and Stroke Patients Go Missing
Emergency physicians are seeing declines in the number of patients arriving with cardiac problems. Some say they were afraid to go to the hospital.
Source: NYT Health - April 25, 2020 Category: Consumer Health News Authors: Gina Kolata Tags: Emergency Medical Treatment Heart Coronavirus (2019-nCoV) Hospitals Stroke Fear (Emotion) Deaths (Fatalities) United States Jaipur (India) Austria Source Type: news

American College of Cardiology urges heart attack, stroke patients to seek medical help
(American College of Cardiology) Through its CardioSmart patient initiative, the American College of Cardiology has issued guidance to encourage patients experiencing a heart attack or stroke to call 911. While hospitals across the United States are experiencing an influx of COVID-19 patients, clinicians are reportedly seeing fewer patients going to emergency rooms for heart attack or stroke. Experts worry that patients who need critical care are delaying their treatment over concerns about the novel coronavirus.
Source: EurekAlert! - Infectious and Emerging Diseases - April 17, 2020 Category: Infectious Diseases Source Type: news

Social Network Simulation Identifies Persistent Racial Disparities Of Delay To Hospital In Acute Ischemic Stroke Patients
Delayed arrival to the hospital remains the major reason for not deploying stroke therapies. In the United States, minority patients have longer delays that have not been adequately understood nor acted upon. Social context plays a key role, because most strokes occur in front of witnesses who influence decision-making. We created a social network simulation to understand the interpersonal factors that influence decision-making following acute stroke, particularly in minority patients.
Source: Journal of Stroke and Cerebrovascular Diseases - April 16, 2020 Category: Neurology Authors: Rachel Greben Tags: Poster 01 Source Type: research

West Virginia Just Became the Last State to Report a COVID-19 Case. It Was Only a Matter of Time
Every U.S. state has now reported at least one confirmed case of COVID-19, following a positive diagnosis out of West Virginia. West Virginia Gov. Jim Justice confirmed the case Tuesday evening, saying it had been detected in the state’s Eastern Panhandle. “This is real and it’s really concerning,” Justice said. The case comes just a day after President Donald Trump praised Justice—who he called “Big Jim” at a Monday press conference—for “doing a good job” in keeping West Virginia free of COVID-19. Doctors, lawmakers and West Virginians were quick to point out, th...
Source: TIME: Health - March 17, 2020 Category: Consumer Health News Authors: Jamie Ducharme Tags: Uncategorized COVID-19 News Desk Source Type: news

Con: Adult Cardiac Surgery Should Not Proceed in the Event of Cardiac Arrest After Induction of Anesthesia
IT IS ESTIMATED that in-hospital cardiac arrest occurs in greater than 290,000 adults each year in the United States.1 In-hospital cardiac arrest has received significantly less attention than other cardiovascular conditions with high risks of morbidity and mortality, such as myocardial infarction, stroke, and out-of-hospital cardiac arrest. Survival to discharge has been estimated at around only 25%. The etiology of in-hospital cardiac arrest is most often owing to cardiac causes (50%-60%), followed by respiratory insufficiency (15%-40%).
Source: Journal of Cardiothoracic and Vascular Anesthesia - March 2, 2020 Category: Anesthesiology Authors: Hamdy Awad, Scott Smith, Islam Shehata, Samiya Saklayen Tags: Pro and Con Source Type: research

Implementation of Best Practices—Developing and Optimizing Regional Systems of Stroke Care: Design and Methodology
Publication date: April 2020Source: American Heart Journal, Volume 222Author(s): Matthew E Ehrlich, Brad J Kolls, Mayme Roettig, Lisa Monk, Shreyansh Shah, Ying Xian, James G Jollis, Christopher B Granger, Carmelo GraffagninoAbstractThe AHA Guidelines recommend developing multi-tiered systems for the care of patients with acute stroke.1 An ideal stroke system of care should ensure that all patients receive the most efficient and timely care, regardless of how they first enter or access the medical care system. Coordination among the components of a stroke system is the most challenging but most essential aspect of any syst...
Source: American Heart Journal - February 4, 2020 Category: Cardiology Source Type: research

let-7g counteracts endothelial dysfunction and ameliorating neurological functions in mouse ischemia/reperfusion stroke model
Publication date: Available online 1 February 2020Source: Brain, Behavior, and ImmunityAuthor(s): David L. Bernstein, Sachin Gajghate, Nancy L. Reichenbach, Malika Winfield, Yuri Persidsky, Nathan A. Heldt, Slava RomAbstractStroke is a debilitating disease, accounting for almost 20% of all hospital visits, and 8% of all fatalities in the United States in 2017. Following an ischemic attack, inflammatory processes originating from endothelial cells within the brain microvasculature can induce many toxic effects into the impacted area, from both sides of the blood brain barrier (BBB). In addition to increased BBB permeability...
Source: Brain, Behavior, and Immunity - February 1, 2020 Category: Neurology Source Type: research

let-7g counteracts endothelial dysfunction and ameliorating neurological functions in mouse ischemia/reperfusion stroke model.
Abstract Stroke is a debilitating disease, accounting for almost 20% of all hospital visits, and 8% of all fatalities in the United States in 2017. Following an ischemic attack, inflammatory processes originating from endothelial cells within the brain microvasculature can induce many toxic effects into the impacted area, from both sides of the blood brain barrier (BBB). In addition to increased BBB permeability, impacted brain microvascular endothelial cells can recruit macrophages and other immune cells from the periphery and can also trigger the activation of microglia and astrocytes within the brain. We have i...
Source: Brain, Behavior, and Immunity - January 31, 2020 Category: Neurology Authors: Bernstein DL, Gajghate S, Reichenbach NL, Winfield M, Persidsky Y, Heldt NA, Rom S Tags: Brain Behav Immun Source Type: research

Implementation of best practices – Developing and optimizing regional Systems of Stroke Care: Design and methodology
Publication date: Available online 15 January 2020Source: American Heart JournalAuthor(s): Matthew E Ehrlich, Brad J Kolls, Mayme Roettig, Lisa Monk, Shreyansh Shah, Ying Xian, James G Jollis, Christopher B Granger, Carmelo GraffagninoAbstractThe AHA Guidelines recommend developing multi-tiered systems for the care of patients with acute stroke.1 An ideal stroke system of care should ensure that all patients receive the most efficient and timely care, regardless of how they first enter or access the medical care system. Coordination among the components of a stroke system is the most challenging but most essential aspect o...
Source: American Heart Journal - January 16, 2020 Category: Cardiology Source Type: research

The Role of Informed Consent for Thrombolysis in Acute Ischemic Stroke.
Authors: Comer AR, Damush TM, Torke AM, Williams LS Abstract Although tissue plasminogen activator (tPA) is the only medication approved by the United States Food and Drug Administration (FDA) for acute ischemic stroke, there is no consensus about the need for informed consent for its use. As a result, hospitals throughout the U.S. have varying requirements regarding obtaining informed consent from patients for the use of tPA, ranging from no requirement for informed consent to a requirement for verbal or written informed consent. We conducted a study to (1) determine current beliefs about obtaining patients' infor...
Source: Journal of Clinical Ethics - December 20, 2019 Category: Medical Ethics Tags: J Clin Ethics Source Type: research

Factors Associated with Inpatient Mortality after Intracerebral Hemorrhage: Updated Information from the United States Nationwide Inpatient Sample
Background: To use a nationwide database of hospital admissions to assess for trends in inpatient mortality from acute spontaneous intracerebral hemorrhage as well as associated potentially contributing factors. Methods: Adults with intracerebral hemorrhage in the US National Inpatient Sample database from 2012 to 2015 were included in this study. We assessed for mortality rate as well as potential impact of various comorbidities and demographic factors such as ethnicity and median house hold income on inpatient mortality rate.
Source: Journal of Stroke and Cerebrovascular Diseases - December 18, 2019 Category: Neurology Authors: Vijayakumar Javalkar, Okkes Kuybu, Debra Davis, Roger E. Kelley Source Type: research