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Condition: Diabetes
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Total 465 results found since Jan 2013.

The Effect of Diabetes and Prediabetes on the Prevalence, Complications and Mortality in Non-alcoholic Fatty Liver Disease
CONCLUSION: Given the increased risk of adverse outcomes, this study highlights the importance of regular diabetes screening in NAFLD and adoption of prompt lifestyle modifications to reduce disease progression. Facing high cardiovascular burden, prediabetic and diabetic NAFLD individuals can benefit from early cardiovascular referrals to reduce risk of CVD events and mortality.PMID:35585687 | DOI:10.3350/cmh.2022.0096
Source: Clinical and molecular hepatology - May 19, 2022 Category: Gastroenterology Authors: Cheng Han Ng Kai En Chan Yip Han Chin Rebecca Wenling Zeng Pei Chen Tsai Wen Hui Lim Darren Jun Hao Tan Chin Meng Khoo Lay Hoon Goh Zheng Jye Ling Anand Kulkarni Lung-Yi Loey Mak Daniel Q Huang Mark Chan Nicholas Ws Chew Mohammad Shadab Siddiqui Arun J Sa Source Type: research

Comparison of Stroke Risk Factors Between Symptomatic and Asymptomatic Patients in a North American Moyamoya Disease Cohort
Conclusions: No significant differences in the prevalence of stroke risk factors between MMD cohorts was found, corroborating evidence provided in a recent Japanese-based study. There were no apparent associations between s troke risk factors and interval cerebrovascular events in an asymptomatic group of MMD patients.
Source: Cerebrovascular Diseases Extra - May 19, 2022 Category: Neurology Source Type: research

Epidemiologic and Genomic Analysis of the Severe Acute Respiratory Syndrome Coronavirus 2 Epidemic in the Nebraska Region of the United States, March 2020 –2021
This report details the epidemiologic and genetic evolution of Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) during the first year of the epidemic in the state of Nebraska using data collected from the Creighton Catholic Health Initiatives (CHI) health system. Statistical modelling identified age, gender, and previous history of diabetes and/or stroke as significant risk factors associated with mortality in COVID-19 patients. In parallel, the viral genomes of over 1,000 samples were sequenced. The overall rate of viral variation in the population was 0.07 mutations/day. Genetically, the first 9 months of...
Source: Frontiers in Microbiology - May 18, 2022 Category: Microbiology Source Type: research

Long-term exposure to ambient fine particulate matter (PM2.5) and associations with cardiopulmonary diseases and lung cancer in Taiwan: a nationwide longitudinal cohort study
ConclusionsLong-term exposure to intermediate levels of ambient PM2.5 was associated with cardiopulmonary health outcomes. Our study adds value to future application and national burden of disease estimation in evaluating the health co-benefits from ambient air pollution reduction policy in Asian countries.
Source: International Journal of Epidemiology - April 26, 2022 Category: Epidemiology Source Type: research

Periodontitis Is Associated With Heart Failure: A Population-Based Study (NHANES III)
Conclusion: According to data from this nationally representative sample from the United States, periodontitis is associated with an increased risk of heart failure.
Source: Frontiers in Physiology - April 20, 2022 Category: Physiology Source Type: research

Implementing federal food service guidelines in federal and private worksite cafeterias in the United States leads to improved health outcomes and is cost saving
AbstractPoor diet increases cardiometabolic disease risk, yet the impact of food service guidelines on employee health and its cost effectiveness is poorly understood. Federal food service guidelines (FFSG) aim to provide United States (U.S.) government employees with healthier food options. Using microsimulation modeling, we estimated changes in the incidence of cardiometabolic disease, related mortality, and the cost effectiveness of implementing FFSG in nationally representative model populations of government and private company employees across 5 years and lifetime. We based estimates on changes in workplace intake of...
Source: Journal of Public Health Policy - April 4, 2022 Category: Health Management Source Type: research

New ERLEADA ® (apalutamide) Analysis Demonstrates Rapid, Deep Prostate-Specific Antigen (PSA) Response in Patients with Metastatic Castration-Sensitive Prostate Cancer (mCSPC)
SAN FRANCISCO, Feb. 14, 2022 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced new real-world evidence data showing the initiation of ERLEADA® (apalutamide) results in high rates of rapid and deep prostate-specific antigen (PSA) response among patients with metastatic castration-sensitive prostate cancer (mCSPC). In a separate post-hoc analysis of the registrational Phase 3 SPARTAN and TITAN studies, rapid and deep PSA responses with ERLEADA® were associated with improvement in patient-reported outcomes (PROs) related to quality of life, physical wellbeing, pain, and fatigue intensity. The...
Source: Johnson and Johnson - February 14, 2022 Category: Pharmaceuticals Tags: Innovation Source Type: news

Evaluating community-driven cardiovascular health policy changes in the United States using agent-based modeling
This study used an agent-based model to estimate long-term impacts of a comprehensive smoke-free policy, as it was implemented in two communities, Arlington and Mesquite, Texas. The model predicted the percentage of myocardial infarction (MI), stroke, and diabetes in the population 10 and 20  years following policy adoption. In Arlington, the percentage of the population with these conditions each decreased by approximately 0.5% over 20 years; in Mesquite, the percentage of the population with diabetes, myocardial infarction (MI), and stroke decreased by 1.1%, 0.6%, and 0.3%, respecti vely, after 20 years. The results w...
Source: Journal of Public Health Policy - February 10, 2022 Category: Health Management Source Type: research

Understanding the relationship between perceived discrimination and mortality in United States adults
CONCLUSIONS: Adults experiencing lifetime and daily discrimination had significantly increased risk of mortality after adjusting for predisposing, enabling, and need factors. The findings highlight the importance of screening patients during clinical encounters for experiences of discrimination and providing appropriate resources to mitigate the negative impact of discriminatory events on mortality. Future research should work to fully understand the mechanism by which discrimination increases risk of mortality. These future findings should be used to develop targets for interventions designed to decrease mortality among a...
Source: Aging and Mental Health - February 4, 2022 Category: Geriatrics Authors: Joanna O Obaoye Aprill Z Dawson Madhuli Thakkar Joni S Williams Leonard E Egede Source Type: research

Can I use DOAC in a patient with renal disease?
Case A 76-year-old man is diagnosed with non-valvular atrial fibrillation. His comorbid conditions are hypertension, diabetes complicated by neuropathy, and chronic kidney disease stage 3. His current medications include metformin, lisinopril, gabapentin, and aspirin. His most recent laboratories showed a creatinine 1.8, creatinine clearance (CrCl) 35 mL/min, hemoglobin 11g/dL, and international normalized ratio 1.0. His congestive heart failure, hypertension, age, diabetes, stroke, vascular disease, and sex (CHADSVASc) score is 4. Which medication should we use to prevent stroke in this patient?  Brief overview of the is...
Source: The Hospitalist - February 3, 2022 Category: Hospital Management Authors: Ronda Whitaker Tags: Renal & Genitourinary Source Type: research

Stroke incidence and outcome disparity in Rural regions of Southern West Virginia
Conclusions: Stroke incidence and mortality were found to be higher than expected in many areas of rural West Virginia. The higher stroke risk populations correlate with area that may be impacted by socioeconomic factors and limited access to primary care. These high-risk areas may therefore benefit from investments in infrastructure, patient education, and unrestricted primary care.
Source: Journal of Emergencies, Trauma and Shock - December 24, 2021 Category: Emergency Medicine Authors: Frank Harrison Annie Mark C Bates Muhammad Khan Salman Zahid Syed Imran Shah Aravinda Nanjundappa Joshua R Wyner Elise Anderson Ali Farooq Megan Wood Abhiram Challa Source Type: research

Pharmacotherapy of obesity in complex diseases
SummaryMore than 40% of adults in the United States suffer from obesity. Obesity is inextricably linked to many chronic illnesses like type-2 diabetes mellitus, hypertension, hyperlipidemia, heart disease, sleep apnea, stroke, and cancers. When used in combination with lifestyle modifications, pharmacotherapy has a vital role in treating obesity and improves short-term and long-term outcomes. A growing number of physicians are now interested in obesity medicine, and many of them are seeking guidance on how to treat complex patients with co-morbidities. This review provides a practical guide to the use of anti-obesity medic...
Source: Clinical Obesity - December 13, 2021 Category: Eating Disorders & Weight Management Authors: Vishnu Priya Pulipati, Silvana Pannain Tags: Review Source Type: research