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Total 794 results found since Jan 2013.
Cerebral autosomal recessive arteriopathy with subcortical infarcts and leukoencephalopathy (CARASIL): A challenging diagnosis and a rare multiple sclerosis mimic
Cerebral autosomal recessive arteriopathy with subcortical infarcts and leukoencephalopathy (CARASIL) is an extremely rare hereditary cerebral small vessel disease caused by homozygous or compound heterozygous mutations in the gene coding for high-temperature requirement A serine peptidase 1 (HtrA1). Given the rare nature of the disease, delays in diagnosis and misdiagnosis are not uncommon. In this article, we reported the first case of CARASIL from Saudi Arabia with a novel homozygous variant c.1156C>T in exon 7 of the HTRA1 gene.
Source: Journal of Stroke and Cerebrovascular Diseases - June 20, 2023 Category: Neurology Authors: Bader Shirah, Hussein Algahtani, Raghad Algahtani, Ahmed Alfares, Ahmed Hassan Tags: Case Report Source Type: research
Association of Genetic and Allelic Variants of Von Willebrand Factor (VWF), Glutathione S-Transferase and Tumor Necrosis Factor Alpha with Ischemic Stroke Susceptibility and Progression in the Saudi Population
Life (Basel). 2023 May 17;13(5):1200. doi: 10.3390/life13051200.ABSTRACTStroke is a key cerebrovascular disease and important cause of death and disability worldwide, including in the kingdom of Saudi Arabia (KSA). It has a large economic burden and serious socioeconomic impacts on patients, their families and the community. The incidence of ischemic stroke is probably increased by the interaction of GSTT1 and GSTM1 null genotypes with high blood pressure, diabetes and cigarette smoking. The roles of VWF, GSTs and TNF-alpha gene variations in the induction of stroke are still uncertain and require further examination. In t...
Source: Atherosclerosis - May 27, 2023 Category: Cardiology Authors: Mohammed M Jalal Rashid Mir Abdullah Hamadi Malik A Altayar Imadeldin Elfaki Jameel Barnawi Almohanad A Alkayyal Mouminah Amr Jabali Hadeel Mamdoh S Moawadh Basim S O Alsaedi Marwan H Alhelali Aadil Yousif Source Type: research
Evidence That Increasing Serum 25(OH)D Concentrations to 30 ng/mL in the Kingdom of Saudi Arabia and the United Arab Emirates Could Greatly Improve Health Outcomes
Biomedicines. 2023 Mar 23;11(4):994. doi: 10.3390/biomedicines11040994.ABSTRACTAccumulating evidence supports the potential protective effects of vitamin D against chronic diseases such as Alzheimer's disease, autoimmune diseases, cancers, cardiovascular disease (ischaemic heart disease and stroke), type 2 diabetes, hypertension, chronic kidney disease, stroke, and infectious diseases such as acute respiratory tract diseases, COVID-19, influenza, and pneumonia, as well as adverse pregnancy outcomes. The respective evidence is based on ecological and observational studies, randomized controlled trials, mechanistic studies, ...
Source: Cancer Control - May 16, 2023 Category: Cancer & Oncology Authors: William B Grant Fatme Al Anouti Barbara J Boucher Hana M A Fakhoury Meis Moukayed Stefan Pilz Nasser M Al-Daghri Source Type: research
Viruses, Vol. 15, Pages 1140: The Risk Factors for Acute Cerebrovascular Accident (Stroke) in Patients with Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV-2)
This study investigates the risk factors, comorbidities, and outcomes in patients with SARS-VoV-2 infection and acute ischemic stroke compared to patients without these conditions. The present retrospective study was conducted in the King Abdullah International Medical Research Centre (KAIMRC), Ministry of National Guard, Health Affairs, Riyadh, Saudi Arabia, during the period from April 2020 to February 2022. This study investigates the risk variables among the individuals who were diagnosed with either SARS-CoV-2 with stroke or patients with stroke alone. A total of 42,688 COVID-19 patients were registered, 187 cases of ...
Source: Viruses - May 10, 2023 Category: Virology Authors: Badi A. Alotaibi Jehad A. Aldali Hamzah J. Aldali Sultan Ayoub Meo Glowi A. Alasiri Emadeldin M. Elsokkary Naser D. Alotaibi Faizah Alotaibi Tags: Article Source Type: research
Patients ’ views and experiences on the use and safety of directly acting oral anticoagulants: a qualitative study
ConclusionsThere is a need to develop and evaluate theory-based interventions to promote patient knowledge, understanding and shared decision-making to optimise DOACs use and improve their safety.
Source: Journal of Pharmaceutical Policy and Practice - May 1, 2023 Category: Pharmaceuticals Source Type: research
‘Full Swing’s Rickie Fowler And Team Drive Viewers Through Pro Golf’s Most “Unprecedented, Controversial” Year
The creators of the Netflix series Full Swing, a compelling look inside the lives of professional golfers, benefitted from a stroke of luck. As they were working on Season 1, the rival Saudi-backed LIV Tour sprang up, posing an existential threat to the venerable PGA Tour. “It’s certainly, I would…#netflix #fullswing #saudi #livtour #pgatour #chadmumm #dustinjohnson #brookskoepka #ianpoulter #liv
Source: Reuters: Health - April 29, 2023 Category: Consumer Health News Source Type: news
Depressive symptoms in diabetic patients; prevalence, correlates, and moderating effect in Taif, Saudi Arabia
CONCLUSIONS: Distress and depression levels are worryingly higher than previous estimates from Saudi Arabia among patients with type II diabetes, indicative of an upward trend and/or a pandemic-related jump. One significant finding from our results is the substantial effect of glycaemic control on increased distress, and depression among our type II diabetes patients. This interaction is likely due to effects on self-care and medication adherence. We also confirmed the association between depressive symptoms and the duration of diabetes. Our results indicated a connection between comorbid medical illness with depressive an...
Source: Primary Care - March 30, 2023 Category: Primary Care Authors: Ameera Mishal Alosaimi Nada Hamed Alsulaimani Wejdan Alotaibi Source Type: research
Saudi-Backed LIV Golf Tour “Very Close” to TV Deal With The CW
Cameron Smith of Punch GC plays his shot from the third tee during the team championship stroke-play round of the LIV Golf Invitational. After a rocky rollout, the LIV Golf tour is closing in on its first U.S. national TV deal. A source familiar with the talks tells The Hollywood Reporter that the…#brookskoepka #newjersey #disney #philmickelson #dustinjohnson #warnerbros #liv #cameronsmith #pga #thrslesleygoldberg
Source: Reuters: Health - January 17, 2023 Category: Consumer Health News Source Type: news
Clinicohistological Profile and Outcomes of Rapidly Progressive Glomerulonephritis: A Prospective Study from North India
This study included 40 patients of biopsy-proven RPGN. The diagnosis of RPGN was based on renal histology showing crescents in >50% of glomeruli. All patients were given induction with intravenous (IV) methylprednisolone (0.5 g) for three days followed by maintenance with oral prednisolone (1 mg/kg/day) and six IV pulses of cyclophosphamide (0.5 g) given fortnightly followed by maintenance therapy with azathioprine (2 mg/kg/day). The outcomes were recorded. Three-fourth of the patients (77.4%) required renal replacement therapy (RRT) at diagnosis. More than half of patients (57.5%) were antineutrophil cytoplasmic antibo...
Source: Saudi Journal of Kidney Diseases and Transplantation - January 17, 2023 Category: Urology & Nephrology Authors: Deepak Sharma Sudhir Mehta Jasvinder Singh Sandhu Preet Mohinder Sohal Vikas Makkar Source Type: research
