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Total 321 results found since Jan 2013.

Stroke Mortality Rates and Trends in Romania, 1994-2017
Background and Aim: Romanian national level stroke mortality data is relatively scarce. The current study investigated stroke mortality rates and trends in Romania. Methods: All individual deaths registered in Romania during 1994-2017 were analyzed using an anonymized database, based on death certificates. Stroke crude mortality rates (CMR) and age-standardized mortality rates (ASMR) were calculated and expressed per 100,000 persons-year. Results: Between 1994 and 2017, 6,281,873 persons died in Romania, stroke being registered as the underlying cause of death in 959,319 cases.
Source: Journal of Stroke and Cerebrovascular Diseases - October 13, 2019 Category: Neurology Authors: Sorin Ioacara, Cristina Tiu, Cristina Panea, Horia Nicolae, Elisabeta Sava, Sorina Martin, Simona Fica Source Type: research

Antiplatelet therapy in secondary ischemic stroke prevention - a short review.
In conclusion, we can say that current recommendations focused primarily on the therapy with aspirin for the secondary prevention of stroke in patients that presented vascular events, such as ischemic stroke of non-cardioembolic cause or transient ischemic attack and, as appropriate, aspirin plus dipyridamol or clopidogrel. The new therapy with ticagrelor in secondary stroke prevention seems to be promising, but more randomized clinical trials are needed to accurately assess the safety and efficacy of this new antiplatelet drug. PMID: 31658310 [PubMed - in process]
Source: Romanian Journal of Morphology and Embryology - October 29, 2019 Category: General Medicine Tags: Rom J Morphol Embryol Source Type: research

Googling the Lifetime Risk of Stroke Around the World
Conclusion: Overall life expectancy is a major driver of the lifetime risk of stroke. The interactive map enables clinicians to search information about the lifetime risk of stroke interactively and navigate by zooming in and out, while still retaining high resolution.
Source: Frontiers in Neurology - July 30, 2020 Category: Neurology Source Type: research

Financial Burden of Stroke Reflected in a Pilot Center for the Implementation of Thrombolysis.
Abstract Stroke represents a serious illness and is extremely relevant from the public health point of view, implying important social and economic burdens. Introducing new procedures or therapies that reduce the costs both in the acute phase of the disease and in the long term becomes a priority for health systems worldwide. The present study quantifies and compares the direct costs for ischemic stroke in patients with thrombolysis treatment versus conservative treatment over a 24-month period from the initial diagnosis, in one of the 7 national pilot centres for the implementation of thrombolytic treatment. The ...
Source: Medicina (Kaunas) - January 27, 2020 Category: Universities & Medical Training Authors: Uivarosan D, Bungau S, Tit DM, Moisa C, Fratila O, Rus M, Bratu OG, Diaconu CC, Pantis C Tags: Medicina (Kaunas) Source Type: research

The 100 most-cited articles about the role of neurovascular unit in stroke 2001-2020: A bibliometric analysis
CONCLUSION: There has been growing attention and efforts made in the field of stroke and NVU. The merit of the above findings may help to shape the research policy in ischemic stroke both at the country and institutional level.PMID:33764687 | DOI:10.1111/cns.13636
Source: CNS Neuroscience and Therapeutics - March 25, 2021 Category: Neuroscience Authors: Lv Xie Bingwei Lu Yezhi Ma Jiemin Yin Xiaozhu Zhai Chen Chen Wanqing Xie Yueman Zhang Li Zheng Peiying Li Source Type: research

Cervical adenocarcinoma generator of procoagulant status and ischemic stroke.
We present the case of a 44-years-old patient undergoing early menopause, who was diagnosed with cervical tumor of the serous adenocarcinoma type. The patient underwent external radiotherapy, and, in the seventh day of treatment, she suffered a frontal-temporal-parietal ischemic stroke with left hemiplegia. The blood testing highlighted procoagulant products (double fibrinogen compared to normal values, deficit of antithrombin and a high number of thrombocytes). The patient received neurological and rehabilitation treatment, at first with Heparin, followed by the administration of an antiaggregant. During this treatment, t...
Source: Romanian Journal of Morphology and Embryology - March 23, 2018 Category: General Medicine Tags: Rom J Morphol Embryol Source Type: research

Predicting functional outcome of ischemic stroke patients in Romania based on plasma CRP, sTNFR-1, D-Dimers, NGAL and NSE measured using a biochip array.
In this study we investigated the utility of a panel of 5 peripheral biomarkers of inflammatory status, neuronal destruction and secondary fibrinolysis in the acute phase of ischemia, and evaluated the impact of these biomarkers on functional outcome after ischemic stroke. The 5 biomarkers (plasma CRP, D-Dimers, sTNFR-1, NGAL and NSE) were measured using a biochip array technology. Eighty nine patients in Romania were divided into 2 subgroups using the modified Rankin Scale evaluated at 3 months after ischemic stroke; the possible impact of analyzed biomarkers on unfavorable functional outcome was tested by binomial logist...
Source: Acta Pharmacologica Sinica - June 21, 2018 Category: Drugs & Pharmacology Authors: Huţanu A, Iancu M, Bălaşa R, Maier S, Dobreanu M Tags: Acta Pharmacol Sin Source Type: research

Expression patterns of aquaporins 1 and 4 in stroke.
Authors: Roşu GC, Pirici I, Istrate-Ofiţeru AM, Iovan L, Tudorică V, Mogoantă L, Gîlceavă IC, Pirici D Abstract Ischemic stroke occurs through embolic or thrombotic obliteration of an artery from cerebral circulation and represents over 80% of all stroke cases. One of the fiercest complications after stroke is edema, which results from imbalanced water diffusion around the blood vessels walls. Water diffusion around blood vessel walls occurs physiologically mainly through two protein-formed pores, namely aquaporins (AQPs) 1 and 4. Here, we compare for the first time the expression patterns and colocalization ...
Source: Romanian Journal of Morphology and Embryology - January 10, 2020 Category: General Medicine Tags: Rom J Morphol Embryol Source Type: research

Remote Ischemic Conditioning in Acute Ischemic Stroke - A Clinical Trial Design.
This study aims to explore the efficiency and safety of remote ischemic conditioning during the first five days following in patients who are ineligible for reperfusion treatment (intravenous thrombolysis or/and mechanical thrombectomy). We hypothesized that this intervention would reduce the infarct size (neuroprotection in the reperfusion window) and improve functional recovery. We aim to conduct a double-blind controlled trial, multicenter in two hospitals in Romania. Two hundred patients with acute ischemic stroke randomly divided into an experimental group and a control group will be included. The subjects in the expe...
Source: Journal of Medicine and Life - August 4, 2020 Category: General Medicine Tags: J Med Life Source Type: research

Equal Opportunities for Stroke Survivors' Rehabilitation: A Study on the Validity of the Upper Extremity Fugl-Meyer Assessment Scale Translated and Adapted into Romanian.
Conclusions: The Romanian version of the UEFMA scale is a reliable, responsive and valid tool which can be used as a standardized assessment in post-stroke patients across Romania. PMID: 32823717 [PubMed - as supplied by publisher]
Source: Medicina (Kaunas) - August 12, 2020 Category: Universities & Medical Training Authors: Roman N, Miclaus R, Repanovici A, Nicolau C Tags: Medicina (Kaunas) Source Type: research

Clinical manifestations and morphological changes in one case with post-stroke Kl üver-Bucy syndrome.
We present the case of a 71-year-old right-handed male, admitted to the Department of Neurology, Emergency County Hospital of Arad, Romania, on November 2015, with a rare case of Klüver-Bucy syndrome (KBS), following an ischemic stroke of the right temporal lobe, which was previously diagnosed in December 2014 and was treated accordingly. At the moment of second hospital admission, the patient was found somnolent and confused at home, with traumatic signs of biting of the tongue and urine emission. A couple days after admission, our patient became alert and presented hypersexuality, hypermetamorphosis, increased oral tend...
Source: Romanian Journal of Morphology and Embryology - July 23, 2017 Category: General Medicine Tags: Rom J Morphol Embryol Source Type: research