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Total 2168 results found since Jan 2013.

History of Carotid Artery Reconstruction around the World and in Japan
Neurol Med Chir (Tokyo). 2023 Apr 20. doi: 10.2176/jns-nmc.2022-0362. Online ahead of print.ABSTRACTSince ancient times, physicians have been aware of correlations between the carotid artery and consciousness; however, carotid stenosis was only recently identified as the cause of atherothrombotic ischemic stroke. In 1658, Wepfer described the first suggestion of a link between symptoms of cerebral arterial insufficiency and carotid pathology. In 1951, Fisher reported details of the symptoms and pathological findings and emphasized that cervical atheromatous lesions induced cerebral infarction with various symptoms. The beg...
Source: Neurologia Medico-Chirurgica - April 21, 2023 Category: Neurosurgery Authors: Masaaki Uno Source Type: research

Significance of coronary artery calcification for predicting major adverse cardiovascular events: results from the NADESICO study in Japan
CONCLUSIONS: Adding assessment of Agatston CAC scores to Suita score was useful to improve the predictive ability for future MACE in Japanese patients. Agatston CAC scores of ≥100 or 200 in male and ≥ 400 in female patients in addition to Suita score improved the MACE risk prediction.PMID:37085027 | DOI:10.1016/j.jjcc.2023.04.006
Source: Journal of Cardiology - April 19, 2023 Category: Cardiology Authors: Shinichi Wada Yoshitaka Iwanaga Michikazu Nakai Yoko M Nakao Yoshihiro Miyamoto Teruo Noguchi NADESICO Study Investigators Source Type: research

Association between complete revascularization of the coronary artery and clinical outcomes in peripheral artery disease: a sub-analysis of the I-PAD Nagano registry
This study was based on a prospective, multicenter, observational registry in Japan. We enrolled 366 patients with PAD undergoing endovascular treatment. The primary endpoint was MACE, defined as a composite of all-cause death, non-fatal myocardial infarction, and non-fatal stroke. After excluding ineligible patients, 96 and 68 patients received complete revascularization of the coronary artery (CR group) and incomplete revascularization of the coronary artery (ICR group), respectively. Freedom from MACE in the CR group was significantly higher than in the ICR group at 5 years (66.7% vs 46.0%, p < 0.01). Multivariate an...
Source: Atherosclerosis - April 13, 2023 Category: Cardiology Authors: Tamon Kato Yasushi Ueki Masatoshi Minamisawa Takashi Miura Yushi Oyama Naoto Hashizume Daisuke Yokota Minami Taki Keisuke Senda Yoshiteru Okina Tadamasa Wakabayashi Koki Fujimori Kenichi Karube Takahiro Sakai Hidetomo Nomi Hisanori Yui Yusuke Kanzaki Keis Source Type: research

Age and sex differences in the risk of cardiovascular diseases by chronic kidney disease in a general Japanese population
We examined 5163 subjects who underwent health screening between 1992 and 1995 with calculated eGFR and follow-up information on CVD events. The mean follow-up period was 10  years. We analyzed the incidences of CVD events, including stroke and myocardial infarction (MI). We compared the risk of CVD between subjects with and without CKD using a Cox proportional hazards model adjusted for well-known CVD confounding factors. The total number of CVD events was 175. The h azard ratios (HRs) for all events, stroke, MI, and sudden death by CKD relative to non-CKD were 1.18 (95% C.I.:0.83–1.68), 0.96 (0.63–1.46), 3.02 (1.2â...
Source: Heart and Vessels - April 11, 2023 Category: Cardiology Source Type: research

National trends in the outcomes of subarachnoid haemorrhage and the prognostic influence of stroke centre capability in Japan: retrospective cohort study
Conclusions The 6-year trends indicated lower in-hospital mortality for patients with SAH (attributable to better outcomes), increased use of coiling and multidisciplinary care for untreated patients. Further increasing CSC capabilities may improve overall outcomes, mainly by increasing the use of coiling. Additional studies are necessary to determine the effect of confounders such as aneurysm complexity on outcomes of clipped patients in the modern endovascular era.
Source: BMJ Open - April 10, 2023 Category: General Medicine Authors: Kurogi, R., Kada, A., Ogasawara, K., Nishimura, K., Kitazono, T., Iwama, T., Matsumaru, Y., Sakai, N., Shiokawa, Y., Miyachi, S., Kuroda, S., Shimizu, H., Yoshimura, S., Osato, T., Horie, N., Nagata, I., Nozaki, K., Date, I., Hashimoto, Y., Hoshino, H., N Tags: Open access, Neurology Source Type: research

Trend in the Numbers of Hospitalized Patients With Varicella, Herpes Zoster, and Ischemic Stroke in Japanese Individuals & lt;20 Years of Age Before and After Implementation of Universal Varicella Vaccination
Pediatr Infect Dis J. 2023 Mar 20. doi: 10.1097/INF.0000000000003907. Online ahead of print.ABSTRACTSeveral studies have shown an association between varicella-zoster virus infection and ischemic stroke. We analyzed the trends in the numbers of patients with varicella, herpes zoster and ischemic stroke before and after the universal vaccination program using a Japanese database of hospitalized patients. The number of patients with varicella decreased but those of herpes zoster and ischemic stroke did not change.PMID:36996309 | DOI:10.1097/INF.0000000000003907
Source: Herpes - March 30, 2023 Category: Infectious Diseases Authors: Soichiro Ishimaru Nobuaki Michihata Yoshiki Kawamura Kazuaki Uda Hiroki Matsui Kiyohide Fushimi Hideo Yasunaga Tetsushi Yoshikawa Source Type: research

Pediatric arterial ischemic stroke in Japan: Moyamoya disease or not
In this study, among 93 responders from physicians in 50 pediatric hospitals, consensus agreement, being available to treat pediatric AIS, was 90.3% in the use of intravenous tissue plasminogen activator (tPA) and 77.4% in mechanical thrombectomy.
Source: Journal of Stroke and Cerebrovascular Diseases - March 27, 2023 Category: Neurology Authors: Shunji Mugikura, Naoko Mori Tags: Letter to the Editor Source Type: research