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Condition: Stroke
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Total 106 results found since Jan 2013.
Genome-wide Study of Atrial Fibrillation Identifies Seven Risk Loci and Highlights Biological Pathways and Regulatory Elements Involved in Cardiac Development
Atrial fibrillation (AF) is a common cardiac arrhythmia and a major risk factor for stroke, heart failure, and premature death. The pathogenesis of AF remains poorly understood, which contributes to the current lack of highly effective treatments. To understand the genetic variation and biology underlying AF, we undertook a genome-wide association study (GWAS) of 6,337 AF individuals and 61,607 AF-free individuals from Norway, including replication in an additional 30,679 AF individuals and 278,895 AF-free individuals.
Source: The American Journal of Human Genetics - December 28, 2017 Category: Genetics & Stem Cells Authors: Jonas B. Nielsen, Lars G. Fritsche, Wei Zhou, Tanya M. Teslovich, Oddgeir L. Holmen, Stefan Gustafsson, Maiken E. Gabrielsen, Ellen M. Schmidt, Robin Beaumont, Brooke N. Wolford, Maoxuan Lin, Chad M. Brummett, Michael H. Preuss, Lena Refsgaard, Erwin P. B Tags: Article Source Type: research
Safety of Moderate Hypothermia With Antegrade Cerebral Perfusion in Total Aortic Arch Replacement
Conclusions In this series, TOTAL with MHCA and ACP can be safely performed with acceptable operative risk. MHCA and ACP represent an effective strategy for TOTAL and may obviate the need for DHCA.
Source: The Annals of Thoracic Surgery - December 10, 2017 Category: Cardiovascular & Thoracic Surgery Source Type: research
Contemporary management and outcomes of acute type A aortic dissection: An analysis of the STS adult cardiac surgery database
ConclusionsThese data describe contemporary patient characteristics, operative strategies, and outcomes for AAAD in North America. Mortality and morbidity for AAAD remain high.
Source: Journal of Cardiac Surgery - December 1, 2017 Category: Cardiovascular & Thoracic Surgery Authors: Teng C. Lee, Zachary Kon, Faisal H. Cheema, Maria V. Grau ‐Sepulveda, Brian Englum, Sunghee Kim, Paramita S. Chaudhuri, Vinod H. Thourani, Gorav Ailawadi, G. Chad Hughes, Matthew L. Williams, J. Matthew Brennan, Lars Svensson, James S. Gammie Tags: ORIGINAL ARTICLE Source Type: research
Relation of Carotid Intima-Media Thickness to Cardiovascular Events in Black Americans (From the Jackson Heart Study)
Although several prospective studies have reported independent relationships between carotid intima-media thickness (CIMT) and risk of incident cardiovascular diseases (CVD) among primarily non-African American (AA) cohorts, the utility of CIMT values for the prediction of incident coronary heart disease and stroke events in blacks remain unclear. At the baseline examination (2000 –2004) of the Jackson Heart Study (JHS), AA adults 21-94 years of age (mean 54) underwent bilateral far-wall CIMT measurement (mean 0.76 mm).
Source: The American Journal of Cardiology - July 31, 2017 Category: Cardiology Authors: Todd C. Villines, Lucy L. Hsu, Chad Blackshear, Cheryl R. Nelson, Michael Griswold Source Type: research
Post-stroke angiotensin II type 2 receptor activation provides long-term neuroprotection in aged rats
by Douglas M. Bennion, Jacob D. Isenberg, Allison T. Harmel, Kelly DeMars, Alex N. Dang, Chad H. Jones, Megan E. Pignataro, Justin T. Graham, U. Muscha Steckelings, Jon C. Alexander, Marcelo Febo, Eric G. Krause, Annette D. de Kloet, Eduardo Candelario-Jalil, Colin Sumners
Activation of the angiotensin II type 2 receptor (AT2R) by administration of Compound 21 (C21), a selective AT2R agonist, induces neuroprotection in models of ischemic stroke in young adult animals. The mechanisms of this neuroprotective action are varied, and may include direct and indirect effec ts of AT2R activation. Our objectives were to assess the...
Source: PLoS One - July 3, 2017 Category: Biomedical Science Authors: Douglas M. Bennion Source Type: research
Inclusion of Pulmonary Embolism Response in a Level I Vascular Emergency Program: A Good Fit in a Collaborative, Multidisciplinary System
The value of a systematic approach for assessment and management of life and limb threatening emergencies has been demonstrated by the success of organized trauma centers, stroke centers, and STEMI programs throughout the United States. Recognizing the applicability of a standardized care process to vascular emergencies, Dr. Michael Dalsing of Indiana University –Methodist Hospital led his academic faculty and hospital in the development of a statewide referral and rapid response system for vascular emergencies in 2009.
Source: Annals of Vascular Surgery - December 14, 2016 Category: Surgery Authors: Charles B. Ross, M. Allene Harrison, Michael P. Lunney, Chad E. Miller, Eyal Ben Arie, Chad Case, William L. Ballard, David A. Dean, W. Morris Brown Tags: Abstracts accepted for presentation during the Florida Vascular Society ’s 29th Annual Scientific Sessions Meeting Source Type: research
Factors associated with stroke in patients with paroxysmal atrial fibrillation beyond CHADS2 score.
CONCLUSIONS: Elevated E velocity, E/E' and SD of tA-SR were associated with occurrence of stroke in patients with PAF even with similar CHAD scores. Increased SD of tA-SR and E/E' were independently associated with stroke in patients with PAF.
PMID: 27296157 [PubMed - as supplied by publisher]
Source: Cardiology Journal - June 13, 2016 Category: Cardiology Authors: Kang MK, Han C, Chun KJ, Choi J, Choi S, Cho JR, Lee N Tags: Cardiol J Source Type: research
Sensory–motor transformations for speech occur bilaterally
Nature advance online publication 15 January 2014. doi:10.1038/nature12935
Authors: Gregory B. Cogan, Thomas Thesen, Chad Carlson, Werner Doyle, Orrin Devinsky & Bijan Pesaran
Historically, the study of speech processing has emphasized a strong link between auditory perceptual input and motor production output. A kind of ‘parity’ is essential, as both perception- and production-based representations must form a unified interface to facilitate access to higher-order language processes such as syntax and semantics, believed to be computed in the dominant, typically left hemisphere. Although various theories ...
Source: Nature AOP - January 15, 2014 Category: Research Authors: Gregory B. CoganThomas ThesenChad CarlsonWerner DoyleOrrin DevinskyBijan Pesaran Tags: Letter Source Type: research
Endocardial Surface Delineation in 3-D Transesophageal Echocardiography
We describe and compare several methods for recovering endocardial walls from 3-D transesophageal echocardiography (3-D TEE), which can help with diagnostics or providing input into biomechanical models. We employ a segmentation method based on 3-D level sets that maximizes enclosed volume while minimizing surface area and uses a growth inhibition function that includes 3-D gradient magnitude (to locate the endocardial walls) and a thin tissue detector (for the mitral valve leaflets). We also study delineation using a graph cut method that performs automated seeding by leveraging a fast radial symmetry transform to determi...
Source: Ultrasound in Medicine and Biology - November 19, 2013 Category: Radiology Authors: Ryan Mukherjee, Saurabh Vyas, Radford Juang, Chad Sprouse, Philippe Burlina Tags: Original Contributions Source Type: research
Austin-area's most affordable hospitals, according to NerdWallet
Scott & White Memorial Hospital in Temple has been named the third-most-affordable hospital in Texas by Nerdwallet.com.
The study looked at the cost of the 100 most common medical procedures in more than 300 Texas hospitals to determine its rankings and also compiled customer satisfaction reports.
Scott & White’s facility – a 636-bed, level I trauma center with 74 percent patient satisfaction – was found to be most affordable in offering treatments for stroke, chronic obstructive pulmonary…
Source: bizjournals.com Health Care:Hospitals headlines - October 11, 2013 Category: Hospital Management Authors: Chad Swiatecki Source Type: research
Five-year results for endovascular repair of acute complicated type B aortic dissection
Conclusions: This study confirms the excellent short-term outcomes of TEVAR for acute complicated type B dissection and demonstrates the results to be durable and sustained over long-term follow-up. Although aortic reinterventions were required in one-quarter of patients, no aortic-related deaths were observed. These data support the use of TEVAR for acute complicated type B aortic dissection but also highlight the importance of life-long aortic surveillance by an experienced aortic referral center in order to identify and treat complications of the underlying disease process and treatment, as well as new aortic pathologies, as they arise.
Source: Journal of Vascular Surgery - October 3, 2013 Category: Surgery Authors: Jennifer M. Hanna, Nicholas D. Andersen, Asvin M. Ganapathi, Richard L. McCann, G. Chad Hughes Tags: Clinical research studies Source Type: research
Trends in Epistaxis Embolization in the United States: A Study of the Nationwide Inpatient Sample 2003–2010—Caveat Emptor
Endovascular embolization for epistaxis is being used more frequently than it has in the past, and the procedure carries a small risk for stroke. These are the only conclusions that can be reliably drawn from the article by Brinjikji et al . Given the nature of the Nationwide Inpatient Sample (NIS) database and the design of this study, comparison of outcomes between embolization and surgical ligation is very limited. The data reported in this article, as presented, suggest that surgical ligation should be preferred over endovascular embolization, owing to a lower stroke rate, and this suggestion is extremely misleading. T...
Source: Journal of Vascular and Interventional Radiology : JVIR - June 25, 2013 Category: Radiology Authors: Chad W. Washington, Colin P. Derdeyn Source Type: research
Predictors of electrocerebral inactivity with deep hypothermia
Conclusions: Cooling to a nasopharyngeal temperature of 12.7°C or for a duration of 97 minutes achieved ECI in>95% of patients in our study population. However, patient-specific factors were poorly predictive of the temperature or cooling time required to achieve ECI, necessitating EEG monitoring for precise ECI detection.
Source: The Journal of Thoracic and Cardiovascular Surgery - April 15, 2013 Category: Cardiovascular & Thoracic Surgery Authors: Michael L. James, Nicholas D. Andersen, Madhav Swaminathan, Barbara Phillips-Bute, Jennifer M. Hanna, Gregory R. Smigla, Michael E. Barfield, Syamal D. Bhattacharya, Judson B. Williams, Jeffrey G. Gaca, Aatif M. Husain, G. Chad Hughes Tags: Acquired Cardiovascular Disease Source Type: research
Type of admission is associated with outcome of spontaneous subarachnoid hemorrhage
ConclusionsSpontaneous subarachnoid hemorrhage patients admitted directly to our comprehensive stroke center showed less complications compared to those transferred from general hospitals. This improvement was independent of time to treatment. Additional research in multiple centers using prospective analysis should be conducted to confirm that preferential direct transport to a comprehensive stroke center would likely yield considerable improvements in public health.
Source: International Journal of Stroke - March 12, 2013 Category: Neurology Authors: Doniel Drazin, Jack Rosner, Miriam Nuño, Michael J. Alexander, Wouter I. Schievink, David Palestrant, Patrick D. Lyden, Chad Miller Tags: Research Source Type: research
