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Rates of Stroke in Patients With Different Presentations of Carotid Artery Stenosis
CONCLUSION: This cohort study showed no large differences in stroke rates among people with different presentations of carotid artery stenosis.PMID:37295600 | DOI:10.1016/j.ejvs.2023.05.041
Source: PubMed: Eur J Vasc Endovasc ... - June 9, 2023 Category: Surgery Authors: Dylan R Morris Tejas P Singh Tahmid Zaman Ramesh Velu Francis Quigley Jason Jenkins Jonathan Golledge Source Type: research

Factors associated with delay to carotid endarterectomy for acute ischaemic stroke in South Australia: A multicentre retrospective cohort study
The greatest benefits of carotid endarterectomy (CEA) accrue when performed within two weeks of acute ischaemic stroke (AIS) due to symptomatic carotid stenosis. Previous studies have identified multiple factors contributing to CEA delay.
Source: Journal of Stroke and Cerebrovascular Diseases - December 22, 2022 Category: Neurology Authors: Rudy Goh, Stephen Bacchi, Joshua G. Kovoor, Aashray K. Gupta, Minh-Son To, Christopher D. Ovenden, Joseph Dawson, Wilson Vallat, David Schultz, Jim Jannes, Timothy Kleinig Source Type: research

Weekend carotid endarterectomies are not associated with a greater risk of stroke and/or death in Australia and New Zealand
Data from multiple surgical studies and settings have reported an increase in adverse events in patients admitted or treated over weekends. The aim of this study was to investigate short-term outcomes for patients undergoing carotid endarterectomy (CEA) in Australia and New Zealand based on the day of surgery.
Source: Annals of Vascular Surgery - August 11, 2020 Category: Surgery Authors: Noha Ferrah, Stuart Robert Walker Tags: Clinical Research, Basic Science Source Type: research

Asymptomatic Carotid Stenosis Is Associated With Circadian and Other Variability in Embolus Detection
Conclusions: Embolism associated with asymptomatic carotid stenosis shows circadian variation with highest rates 4–6 h before midday. This corresponds with peak circadian incidence of stroke and other vascular complications. These and ASED Study results show that monitoring frequency, duration, and time of day are important in ES detection. Introduction Transcranial Doppler (TCD) detected microembolism in the ipsilateral middle cerebral artery (MCA) may help stratify the risk of stroke and other arterial disease complications in persons with advanced (≥60%) asymptomatic carotid stenosis. If so, this t...
Source: Frontiers in Neurology - April 15, 2019 Category: Neurology Source Type: research

Stenosis Length and Degree Interact With the Risk of Cerebrovascular Events Related to Internal Carotid Artery Stenosis
Conclusion: We found a statistically insignificant tendency for the ultrasound-measured length of sICAS<70% to be longer than that of sICAS≥70%. Moreover, the ultrasound-measured length of sICAS<90% was significantly longer than that of sICAS 90%. Among patients with sICAS≥70%, the degree and length of stenosis were inversely correlated. Larger studies are needed before a clinical implication can be drawn from these results. Introduction Internal carotid artery stenosis (ICAS) causes around one-fifth of ischemic cerebrovascular stroke and has the highest risk of early stroke recurrence...
Source: Frontiers in Neurology - April 8, 2019 Category: Neurology Source Type: research

Cardiovascular disease and use of contemporary protease inhibitors: the D:A:D international prospective multicohort study
Publication date: June 2018Source: The Lancet HIV, Volume 5, Issue 6Author(s): Lene Ryom, Jens D Lundgren, Wafaa El-Sadr, Peter Reiss, Ole Kirk, Matthew Law, Andrew Phillips, Rainer Weber, Eric Fontas, Antonella d' Arminio Monforte, Stéphane De Wit, Francois Dabis, Camilla I Hatleberg, Caroline Sabin, Amanda Mocroft, D:A:D study groupSummaryBackgroundAlthough earlier protease inhibitors have been associated with increased risk of cardiovascular disease, whether this increased risk also applies to more contemporary protease inhibitors is unknown. We aimed to assess whether cumulative use of ritonavir-boosted atazanavir and...
Source: The Lancet HIV - July 10, 2018 Category: Infectious Diseases Source Type: research

Carotid endarterectomy: the change in practice over 11  years in a stroke centre
ConclusionThe trends in CEA practice at our centre align with international trends and guidelines. This study provides a representative indicator of Australian hospital practice, and illustrates how evidence from research is translated into clinical care.
Source: ANZ Journal of Surgery - November 13, 2017 Category: Surgery Authors: Gabrielle T. W. Tse, Monique F. Kilkenny, Chris Bladin, Michael Grigg, Helen M. Dewey Tags: Original Article Source Type: research