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Cholangiocarcinoma manifesting as non-bacterial thrombotic endocarditis in a young patient
A 41-year-old female with steroid-dependent rheumatoid arthritis and a recent (four months prior) cerebellar stroke presented with complaints of constant headache and right eye blindness of one day.  At the time of the cerebellar stroke, she had presented with persistent headaches, dizziness and gait instability. That workup, including hypercoagulability evaluation, was unremarkable apart from the radiographic abnormalities diagnosing her left medial cerebellar hemisphere infarct. She was disc harged with a plan for outpatient loop recorder placement and aspirin for secondary stroke prevention.
Source: The American Journal of Medicine - January 23, 2020 Category: General Medicine Authors: Ninad Nadkarni, Young Ju Lee, Ryan Hoefen, Richard Alweis Tags: Diagnostic Dilemma Source Type: research

Bilateral visual loss and cerebral infarction after spleen embolization in a trauma patient with idiopathic thrombocytopenic purpura: A case report
We report a case of acute ischemic stroke following orthopedic surgery in a patient with post-SAE reactive thrombocytosis. Patient concerns: A 37-year-old woman with idiopathic thrombocytopenic purpura (ITP) suffered from multiple trauma scheduled for open reduction and internal fixation for right tibial and left radius fracture five days after SAE. The patient did not have any thromboembolic complications, although the platelet counts increased from 43 × 109/L to 568 × 109/L within two days after SAE. Surgery was completed under general anesthesia with tracheal intubation without complications. The patient co...
Source: Medicine - April 1, 2018 Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research

Embolization for the treatment of intractable epistaxis: 12 month outcomes in a two centre case series.
CONCLUSION: Embolization for epistaxis is safe and effective. Of those who had recurrent epistaxis post embolization, most were taking P2Y12 inhibition and/or anticoagulation. We prefer bilateral distal internal maxillary artery and unilateral facial artery embolization under general anesthesia for optimal safety and efficacy. Advances in knowledge: Embolization with this technique seems to facilitate superior outcomes without complications despite the large proportion of patients taking anticoagulating or P2Y12 inhibiting agents. PMID: 28972795 [PubMed - as supplied by publisher]
Source: The British Journal of Radiology - October 3, 2017 Category: Radiology Authors: Robinson AE, McAuliffe W, Phillips TJ, Phatouros CC, Singh TP Tags: Br J Radiol Source Type: research

P-021 Very Delayed Monocular Blindness Following Flow Diversion Treatment of Ophthalmic Artery Aneurysm
ConclusionMonocular vision loss remains a risk, even months to years following flow diversion of ICA aneurysms. Long term clinical follow-up is necessary to define the incidence of this complication.Abstract P-021 Figure 1DisclosuresT. Higashimori: None. D. Sandhu: None. J. Kim: None. A. Grande: None. M. Ezzeddine: None. R. Tummala: None. B. Jagadeesan: None.
Source: Journal of NeuroInterventional Surgery - July 28, 2016 Category: Neurosurgery Authors: Higashimori, T., Sandhu, D., Kim, J., Grande, A., Ezzeddine, M., Tummala, R., Jagadeesan, B. Tags: Oral poster abstracts Source Type: research

Anton–Babinski syndrome in an old patient: a case report and literature review
Abstract Anton–Babinski syndrome is a rare disease featuring bilateral cortical blindness and anosognosia with visual confabulation, but without dementia or any memory impairment. It has a unique neuropsychiatric presentation and should be highly suspected in those with odd visual loss and imaging evidence of occipital lobe injury. In the case discussed herein, a 90‐year‐old man presented with bilateral blindness, obvious anosognosia, and vivid visual confabulation, which he had had for 3 days. Brain computed tomography demonstrated recent hypodense infarctions at the bilateral occipital lobes. Thus, the patient was ...
Source: Psychogeriatrics - December 16, 2014 Category: Geriatrics Authors: Jiann‐Jy Chen, Hsin‐Feng Chang, Yung‐Chu Hsu, Dem‐Lion Chen Tags: CASE REPORT Source Type: research

Screening and Treatment by the Primary Care Provider of Common Diabetes Complications.
Abstract Diabetes is the leading cause of end-stage renal disease, blindness, and nontraumatic lower-limb amputation. The largest reductions in cardiovascular events are seen when multiple risk factors are addressed simultaneously. The benefit of aspirin as secondary prevention in patients with previous stroke or myocardial infarction has been well established. Regular, dilated eye examinations are effective in detecting sight-threatening diabetic retinopathy and have been shown to prevent blindness. The use of appropriate tools and clinical examination/inspection provides greater than 87% specificity in detecting...
Source: The Medical Clinics of North America - December 8, 2014 Category: Journals (General) Authors: Gilbert MP Tags: Med Clin North Am Source Type: research

Screening and Treatment by the Primary Care Provider of Common Diabetes Complications
Diabetes is the leading cause of end-stage renal disease, blindness, and nontraumatic lower-limb amputation. The largest reductions in cardiovascular events are seen when multiple risk factors are addressed simultaneously. The benefit of aspirin as secondary prevention in patients with previous stroke or myocardial infarction has been well established. Regular, dilated eye examinations are effective in detecting sight-threatening diabetic retinopathy and have been shown to prevent blindness. The use of appropriate tools and clinical examination/inspection provides greater than 87% specificity in detecting diabetic peripher...
Source: Medical Clinics of North America - October 27, 2014 Category: Primary Care Authors: Matthew P. Gilbert Source Type: research

Aspirin-Responsive, Migraine-Like Transient Cerebral and Ocular Ischemic Attacks and Erythromelalgia in JAK2-Positive Essential Thrombocythemia and Polycythemia Vera.
Abstract Migraine-like cerebral transient ischemic attacks (MIAs) and ocular ischemic manifestations were the main presenting features in 10 JAK2(V617F)-positive patients studied, with essential thrombocythemia (ET) in 6 and polycythemia vera (PV) in 4. Symptoms varied and included cerebral ischemic attacks, mental concentration disturbances followed by throbbing headaches, nausea, vomiting, syncope or even seizures. MIAs were frequently preceded or followed by ocular ischemic events of blurred vision, scotomas, transient flashing of the eyes, and sudden transient partial blindness preceded or followed erythromela...
Source: Acta Haematologica - August 7, 2014 Category: Hematology Authors: Michiels JJ, Berneman Z, Gadisseur A, Lam KH, De Raeve H, Schroyens W Tags: Acta Haematol Source Type: research

An audit of management practices in patients with suspected temporary monocular blindness
Conclusion There is a need to improve professional awareness of the importance of starting best medical therapy and performing CEA as soon as possible after onset of TMB.
Source: British Journal of Ophthalmology - May 17, 2014 Category: Opthalmology Authors: Naylor, A. R., Robinson, T. G., Eveson, D., Burns, J. Tags: Public health, Vision, Neurology Original articles - Clinical science Source Type: research

An audit of management practices in patients with suspected temporary monocular blindness.
CONCLUSION: There is a need to improve professional awareness of the importance of starting best medical therapy and performing CEA as soon as possible after onset of TMB. PMID: 24187055 [PubMed - as supplied by publisher]
Source: The British Journal of Ophthalmology - November 1, 2013 Category: Opthalmology Authors: Naylor AR, Robinson TG, Eveson D, Burns J Tags: Br J Ophthalmol Source Type: research

Aspirin Linked To Blinding Eye Disease
WebMD Medical News By Brenda Goodman, MA Reviewed by Laura J. Martin, MD Jan. 22, 2013 — Regular aspirin users are more likely to develop the “wet” form of age-related macular degeneration compared to people who rarely or never take the drug, a new study shows. Aspirin is one of the most widely used drugs in the world. Millions of people with heart disease take a daily low dose of aspirin in hopes of preventing heart attacks and stroke. It’s also used to ease pain. Macular degeneration is a leading cause of blindness in older adults, and it is on the rise. The “wet” form accounts for on...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - January 23, 2013 Category: Consumer Health News Authors: mreal197 Tags: WebMD News Source Type: news

Long-term aspirin use 'increases blindness risk'
Conclusion This cohort study has suggested that there may be a link between aspirin use and risk of developing wet AMD. The main strengths of this study are that it followed people up over a long time, collected data prospectively and carried out thorough eye examinations for AMD. This means that cases of AMD were not likely to be missed. However, it should be noted that: The study’s main weakness was that, as a cohort study, its results may be affected by confounding, although the researchers did try to take into account factors that could be having an effect. Confounding ‘by indication’ is a possibility; this is...
Source: NHS News Feed - January 22, 2013 Category: Consumer Health News Tags: Lifestyle/exercise Medication Source Type: news

Regular Aspirin Linked To Age-Related Macular Degeneration Risk
People who take aspirin regularly over the long-term have a higher risk of developing age-related macular degeneration (AMD), the main cause of blindness among seniors, researchers from the University of Sydney, Australia, reported in JAMA Internal Medicine. Aspirin is commonly taken by patients to protect from cardiovascular disease, including ischemic stroke and heart attack (myocardial infarction). It is one of the most widely used drugs worldwide...
Source: Health News from Medical News Today - January 22, 2013 Category: Consumer Health News Tags: Eye Health / Blindness Source Type: news

Regular aspirin use linked to blindness
Study finds increased risk of age-related macular degeneration in people who take aspirin regularlyRelated items from OnMedicaAspirin may be too risky for blanket primary preventionAspirin as effective as warfarin for heart patientsDaily aspirin use linked to major bleedingBenefits of statins 'still outweigh risks'Avoid BP-lowering drugs in stroke
Source: OnMedica Latest News - January 22, 2013 Category: UK Health Source Type: news