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Condition: Alcoholism
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Total 62 results found since Jan 2013.

'Exercise pill' could potentially help people with heart failure
Conclusion The protein hCT1 caused heart muscles to grow in a more healthy way in rodents with heart failure. When treatment stopped, the heart went back to its original condition – something that does not happen when the heart grows in a dysfunctional way. There is currently no cure for heart failure and treatment is only available for keeping symptoms under control. Therefore, this very promising early-stage research with potential for developing a drug for people with heart failure, has huge implications. However, it is important to remember that as this is experimental laboratory research, there are many more stage...
Source: NHS News Feed - August 9, 2017 Category: Consumer Health News Tags: Heart/lungs Source Type: news

The Association of Arsenic Metabolism with Cancer, Cardiovascular Disease, and Diabetes: A Systematic Review of the Epidemiological Evidence
Conclusions: Population level of iAs% and DMA%, but not MMA%, were associated with arsenic exposure levels. Overall, study findings suggest that higher MMA% was associated with an increased risk of cancer and cardiovascular disease, while lower MMA% was associated with an increased risk of diabetes and metabolic syndrome. Additional population-based studies and experimental studies are needed to further evaluate and understand the role of arsenic exposure in arsenic metabolism and the role of arsenic metabolism in disease development. https://doi.org/10.1289/EHP577 Received: 01 June 2016 Revised: 26 February 2017 Acce...
Source: EHP Research - August 2, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research

Fetal Alcohol Exposure Alters Blood Flow and Neurological Responses to Transient Cerebral Ischemia in Adult Mice.
CONCLUSIONS: Our data collectively show that PAE adult mice exhibit a persistent, long-term loss of cranially directed blood flow, and decreased capacity to compensate for brain trauma due to acute-onset adult diseases like ischemic stroke. PMID: 27987329 [PubMed - as supplied by publisher]
Source: Alcoholism, Clinical and Experimental Research - December 16, 2016 Category: Addiction Authors: Bake S, Gardner R, Tingling JD, Miranda RC, Sohrabji F Tags: Alcohol Clin Exp Res Source Type: research

Fetal Alcohol Exposure Alters Blood Flow and Neurological Responses to Transient Cerebral Ischemia in Adult Mice
ConclusionsOur data collectively show that PAE adult mice exhibit a persistent, long‐term loss of cranially directed blood flow, and decreased capacity to compensate for brain trauma due to acute‐onset adult diseases like ischemic stroke. Our study assessed long‐term consequences of prenatal alcohol exposure (PAE) on blood flow and on behavioral outcomes following unilateral middle cerebral artery occlusion (MCAo)‐induced transient ischemic stroke in adults. PAE resulted in a significant age‐related decrease in blood acceleration in mature adult and middle‐aged mice, specifically in the carotid artery. Followi...
Source: Alcoholism: Clinical and Experimental Research - December 16, 2016 Category: Addiction Authors: Shameena Bake, Rachel Gardner, Joseph D. Tingling, Rajesh C. Miranda, Farida Sohrabji Tags: Original Article Source Type: research

Sex differences in the integrated stroke management in a rural healthcare area in Asturias.
CONCLUSIONS: There are demographic sex differences in the cerebrovascular risk profile, clinical presentation, hospital management and comorbidity of stroke in this rural population, which suggest that there are areas where there is room for improvement. PMID: 27439484 [PubMed - in process]
Source: Revista de Neurologia - July 23, 2016 Category: Neurology Authors: Lopez-Martinez T, Bernardo-Cofino J, Garcia-Prieto E, Feito-Alvarez M, de Dios-Del Valle R, Calleja-Puerta S Tags: Rev Neurol Source Type: research

Optimal Acquisition Settings for Speckle Tracking Echocardiography–Derived Strains in Infants: An In Vitro Study
The purpose of this study was to investigate the effect of frame rate and probe frequency on the accuracy of speckle tracking echocardiography–derived strain measurements in infants. An infant-sized left ventricle phantom with sonomicrometer crystals was made from polyvinyl alcohol. The examined stroke rates were 60, 120 and 180 strokes per min (SPM). Longitudinal strain and circumferential strain measurements were analyzed from a total of 1860 cine loops. These cine loops were acquired using two pediatric probes of different frequencies at both fundamental and harmonic imaging modes.
Source: Ultrasound in Medicine and Biology - April 12, 2016 Category: Radiology Authors: Umael Khan, Johannes Just Hjertaas, Gottfried Greve, Knut Matre Tags: Original Contribution Source Type: research

Risk Factors for Silent Lacunar Infarction in Patients with Transient Ischemic Attack.
CONCLUSIONS Age, hypertension, hyperlipidemia, and carotid stenosis were independently associated with silent lacunar infarction in patients with TIA. PMID: 26864634 [PubMed - in process]
Source: Medical Science Monitor - February 14, 2016 Category: Research Tags: Med Sci Monit Source Type: research

Causes of changes in carotid intima-media thickness: a literature review
Atherosclerosis causes significant morbidity and mortality. Carotid intima-media thickness (CIMT) predicts future cardiovascular and ischaemic stroke incidence. CIMT, a measure of atherosclerotic disease, can be reliably determined in vivo by carotid ultrasound. In this review, we determined that CIMT is associated with traditional cardiovascular risk factors such as age, sex, race, smoking, alcohol consumption, habitual endurance exercise, blood pressure, dyslipidemia, dietary patterns, risk-lowering drug therapy, glycemia, hyperuricemia, obesity-related anthropometric parameters, obesity and obesity-related diseases. We ...
Source: Cardiovascular Ultrasound - December 15, 2015 Category: Radiology Authors: Baoge QuTao Qu Source Type: research

On ultrasound classification of stroke risk factors from randomly chosen respondents using non-invasive multispectral ultrasonic brain measurements and adaptive profiles
Publication date: Available online 24 October 2015 Source:Biocybernetics and Biomedical Engineering Author(s): Miroslaw Wrobel, Andrzej Dabrowski, Adam Kolany, Anna Olak-Popko, Robert Olszewski, Pawel Karlowicz In this paper, we present a new brain diagnostic method based on a computer aided multispectral ultrasound diagnostics method (CAMUD). We explored the standard values of the relative time of flight (RIT), as well as the attenuation, ATN, of multispectral longitudinal ultrasound waves propagated non-invasively through the brains of a standard Caucasian volunteer population across different ages and genders. F...
Source: Biocybernetics and Biomedical Engineering - October 25, 2015 Category: Biomedical Engineering Source Type: research

Medtech approvals: FDA releases August 2015 PMAs
The FDA today released its list of the pre-market approvals it granted for medical devices in August 2015: Summary of PMA Originals & Supplements Approved Originals: 2 Supplements: 70 Summary of PMA Originals Under Review Total Under Review: 57 Total Active: 28 Total On Hold: 29 Summary of PMA Supplements Under Review Total Under Review: 569 Total Active: 422 Total On Hold: 147 Summary of All PMA Submissions Originals: 5 Supplements: 90 Summary of PMA Supplement PMA Approval/Denial Decision Times Number of Approvals: 70 Number of Denials: 0 Average Days Fr Receipt to Decision (Total Time): 229.0 FDA Time: 130...
Source: Mass Device - October 23, 2015 Category: Medical Equipment Authors: Brad Perriello Tags: Food & Drug Administration (FDA) Pre-Market Approval (PMA) Regulatory/Compliance Source Type: news

Deep-fried Mars bars – unhealthy, but no killer
Conclusion This study found no significant differences in cerebrovascular reactivity (the body’s ability to respond to breath holding by increasing blood flow to the brain) after eating either a deep-fried Mars bar or porridge. When the researchers analysed men and women separately, they found no significant differences in cerebrovascular reactivity after eating a deep-fried Mars bar or porridge. However, when the researchers compared men with women, they found a significant difference, although whether there is any clinical significance to this finding is unclear. The researchers point out that there are limitations to ...
Source: NHS News Feed - September 30, 2014 Category: Consumer Health News Tags: Food/diet Neurology Obesity Source Type: news

Deep-fried Mars bars: unhealthy, but no killer
Conclusion This study found no significant differences in cerebrovascular reactivity (the body’s ability to respond to breath holding by increasing blood flow to the brain) after eating either a deep-fried Mars bar or porridge. When the researchers analysed men and women separately, they found no significant differences in cerebrovascular reactivity after eating a deep-fried Mars bar or porridge. However, when the researchers compared men with women, they found a significant difference, although whether there is any clinical significance to this finding is unclear. The researchers point out that there are limitations to ...
Source: NHS News Feed - September 30, 2014 Category: Consumer Health News Tags: Food/diet Neurology Obesity Source Type: news

Abuse and Subclinical Cardiovascular Disease Among Midlife Women: The Study of Women's Health Across the Nation Clinical Sciences
Conclusions— Childhood sexual abuse was associated with higher intima media thickness controlling for CVD risk factors and other confounders. These findings indicate the importance of considering the potential impact of early-life stressors on women’s later cardiovascular health.
Source: Stroke - July 28, 2014 Category: Neurology Authors: Thurston, R. C., Chang, Y., Derby, C. A., Bromberger, J. T., Harlow, S. D., Janssen, I., Matthews, K. A. Tags: Epidemiology Clinical Sciences Source Type: research

E-006 Familial Incidence of the Congenital Torcular Dural Arteriovenous Shunt
Purpose There are several hereditary disorders that are well known to be associated with arteriovenous malformations (AVMs) involving the central nervous system including Sturge-Weber, Klippel-Trenaunay-Weber, and Parkes-Weber syndromes as well as hereditary haemorrhagic telangiectasia and hereditary neurocutaneous angiomatosis. Furthermore, familial incidence of AVMs in the absence of congenital hereditary disorders also has been reported. Herein, we describe the occurrence of the giant torcular herophili (TH) dural arteriovenous fistula (AVF) in two pediatric cousins treated with endovascular embolization. Case report C...
Source: Journal of NeuroInterventional Surgery - July 26, 2014 Category: Neurosurgery Authors: Honarmand, A., Hurley, M., Daruwalla, V., Ansari, S., Shaibani, A. Tags: Electronic poster abstracts Source Type: research

Parental smoking 'ages' children’s arteries
ConclusionOverall, this secondary analysis study provides preliminary evidence of the effects of parental passive smoking on the artery walls of children and adolescents in adulthood. The researchers attempted to adjust for potential factors that could influence risk (confounders), such as: age sex height weight smoking status physical activity levels alcohol consumption schooling level of the parent(s)In their analysis, they also took into consideration cardiovascular risk factors of the participants in adulthood. There are some limitations to the study, which are worth noting. Parental smoking status was self-re...
Source: NHS News Feed - March 5, 2014 Category: Consumer Health News Tags: Heart/lungs Pregnancy/child Source Type: news