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A Nomogram Model for Predicting Prognosis in Spontaneous Intracerebral Hemorrhage Patients
CONCLUSIONS: ICH score, GCS score, irregular shape, uneven density, IVH relation, surgery are easily available indicators to assist neurologists in formulating the most appropriate therapy for every intracranial hemorrhage patient. Further large prospective clinical trials are needed to obtain more integrated and reliable conclusions.PMID:36992585 | DOI:10.31083/j.jin2202042
Source: Journal of Integrative Neuroscience - March 30, 2023 Category: Neuroscience Authors: Yunjie Li Xia Liu Jingxuan Wang Chao Pan Zhouping Tang Source Type: research

Risk factors of impaired employability after cerebral venous thrombosis
CONCLUSIONS: Impaired employability after CVT was associated with motor deficits, aphasia, mental status disorders, and NIHSS score at admission. Even if they recover from CVT without physical disability, patients with a good functional prognosis have a higher risk of employment failure due to their higher rates of aphasia and CVT recurrence.PMID:36601664 | DOI:10.1111/cns.14083
Source: CNS Neuroscience and Therapeutics - January 5, 2023 Category: Neuroscience Authors: Lu Liu Huimin Jiang Huimin Wei Yifan Zhou Yan Wu Kaiyuan Zhang Jiangang Duan Ran Meng Chen Zhou Xunming Ji Source Type: research

Cerebral Ischemia/Reperfusion Injury and Pharmacologic Preconditioning as a Means to Reduce Stroke-induced Inflammation and Damage
Neurochem Res. 2022 Nov 3. doi: 10.1007/s11064-022-03789-5. Online ahead of print.ABSTRACTStroke is one of the leading causes of death and long-term serious disability. Current therapeutic strategy is limited to thrombolytic agents, consequently, boosting endogenous neuroprotective mechanisms of the brain to protect itself against harmful stimuli and restore from damages are widely studied. Preconditioned brain to tolerate cerebral ischemia/reperfusion injury could be initiated by several different pharmacological and mechanical strategies, such as ischemic preconditioning, ethanol pharmacological preconditioning and other...
Source: Neurochemical Research - November 3, 2022 Category: Neuroscience Authors: Huajun Yang Chengxuan Qi Fang Su Wei Shan Anchen Guo Jianping Wu Yongjun Wang Hong You Qun Wang Source Type: research

Carvedilol reduces the Neuronal apoptosis after ischemic stroke by modulating ATF3 expression in vitro
In conclusion, Carvedilol may be a key compound targeting ATF3 in OGD/R-PC12 cells.
Source: Developmental Neuroscience - October 11, 2022 Category: Neuroscience Source Type: research

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