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Condition: Thrombosis
Infectious Disease: Pandemics

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Total 181 results found since Jan 2013.

Recognizing Vaccine-Induced Immune Thrombotic Thrombocytopenia
CONCLUSIONS: Vaccine-induced immune thrombotic thrombocytopenia is a serious complication of vaccination that is not feasible to anticipate or prevent. When the patient presents with sustained headache, neurologic symptoms/signs, abdominal pain, dyspnea, or limb pain/swelling beginning 5–30 days post vaccination, platelet count and d-dimer must be measured, and imaging for thrombosis performed. Confirmation of vaccine-induced immune thrombotic thrombocytopenia diagnosis should be ordered (platelet factor 4/polyanion enzyme-linked immunosorbent assay; platelet factor 4–enhanced platelet activation testing) as treatm...
Source: Critical Care Medicine - December 20, 2021 Category: Emergency Medicine Tags: Online Review Article Source Type: research

Twelfth Interagency Registry for Mechanically Assisted Circulatory Support Report: Readmissions after LVAD
Ann Thorac Surg. 2022 Jan 7:S0003-4975(22)00007-8. doi: 10.1016/j.athoracsur.2021.12.011. Online ahead of print.ABSTRACTThe twelfth annual report from the Society of Thoracic Surgeons (STS) Interagency Registry for Mechanically Assisted Circulatory Support (Intermacs) highlights outcomes for 26,688 continuous-flow LVAD patients over the past decade (2011-2020). In 2020, we observed the largest drop in yearly LVAD implant volumes since the registry's inception, which reflects the effects of the COVID-19 pandemic on cardiac surgical volumes in the United States. The 2018 heart transplant allocation policy change in the U.S. ...
Source: The Annals of Thoracic Surgery - January 10, 2022 Category: Cardiovascular & Thoracic Surgery Authors: Palak Shah Melana Yuzefpolskaya Gavin W Hickey Khadijah Breathett Omar Wever-Pinzon Van Khue-Ton William Hiesinger Devin Koehl James K Kirklin Ryan S Cantor Jeffrey P Jacobs Robert H Habib Francis D Pagani Daniel J Goldstein Source Type: research

SARS-CoV-2 interacts with renin-angiotensin system: impact on the central nervous system in elderly patients
AbstractSARS-CoV-2 is a recently identified coronavirus that causes the current pandemic disease known as COVID-19. SARS-CoV-2 uses angiotensin-converting enzyme 2 (ACE2) as a receptor, suggesting that the initial steps of SARS-CoV-2 infection may have an impact on the renin-angiotensin system (RAS). Several processes are influenced by RAS in the brain. The neurological symptoms observed in COVID-19 patients, including reduced olfaction, meningitis, ischemic stroke, cerebral thrombosis, and delirium, could be associated with RAS imbalance. In this review, we focus on the potential role of disturbances in the RAS as a cause...
Source: AGE - February 14, 2022 Category: Geriatrics Source Type: research

The hospitalization rate of cerebral venous sinus thrombosis before and during COVID-19 pandemic era: A single-center retrospective cohort study
In this study, we aimed to compare the hospitalization rate of CVST before and during the COVID-19 pandemic (before vaccination program).
Source: Journal of Stroke and Cerebrovascular Diseases - March 24, 2022 Category: Neurology Authors: Maryam Vasaghi Gharamaleki, Maryam Habibagahi, Etrat Hooshmandi, Reza Tabrizi, Shahram Arsang-Jang, Zohreh Barzegar, Nima Fadakar, Vahid Reza Ostovan, Abbas Rahimi-Jaberi, Nahid Ashjazadeh, Peyman Petramfar, Maryam Poursadeghfard, Sadegh Izadi, Masoumeh N Source Type: research

Cardiac Registries During the COVID-19 Pandemic: Lessons Learned
AbstractPurpose of this ReviewWe discuss the role of observational studies and cardiac registries during the COVID-19 pandemic. We focus on published cardiac registries and highlight contributions to the field that have had clinical implications.Recent FindingsWe included observational studies of COVID-19 patients published in peer-reviewed medical journals with defined inclusion and exclusion criteria, defined study design, and primary outcomes. A PubMed and MEDLINE literature review results in 437 articles, of which 52 include patients with COVID-19 with cardiac endpoints. From July 2020 to December 2021, the average tim...
Source: Current Cardiology Reports - April 5, 2022 Category: Cardiology Source Type: research

The Hospitalization Rate of Cerebral Venous Sinus Thrombosis before and during COVID-19 Pandemic Era: A Single-Center Retrospective Cohort Study
CONCLUSION: Since there was a more dismal outcome in COVID-19 associated CVST, a high index of suspicion for CVST among COVID-19 positive is recommended.PMID:35523051 | PMC:PMC8947940 | DOI:10.1016/j.jstrokecerebrovasdis.2022.106468
Source: Atherosclerosis - May 6, 2022 Category: Cardiology Authors: Maryam Vasaghi Gharamaleki Maryam Habibagahi Etrat Hooshmandi Reza Tabrizi Shahram Arsang-Jang Zohreh Barzegar Nima Fadakar Vahid Reza Ostovan Abbas Rahimi-Jaberi Nahid Ashjazadeh Peyman Petramfar Maryam Poursadeghfard Sadegh Izadi Masoumeh Nazeri Hanieh Source Type: research

Preface: COVID-19 Pandemic: Direct and Indirect Cardiovascular Effects
The COVID-19 pandemic has had a dramatic impact on the care of patients with cardiovascular disease throughout the world. COVID-19 has a myriad of direct effects on the myocardium, vasculature and coagulation cascade, related to the pro-inflammatory and prothrombotic effects of the virus, leading to an increase risk of myocardial infarction, stroke, deep venous thrombosis (DVT), and pulmonary emboli within the first 2-4 weeks of contracting the disease. Patients with pre-existent cardiovascular disease and/or cardiovascular risk factors such as hypertension and diabetes are particularly susceptible to suffer complications ...
Source: Cardiology Clinics - May 11, 2022 Category: Cardiology Authors: Timothy D. Henry, Santiago Garcia Source Type: research

COVID-19 Pandemic: Direct and Indirect Cardiovascular Effects
The COVID-19 pandemic has had a dramatic impact on the care of patients with cardiovascular disease throughout the world. COVID-19 has a myriad of direct effects on the myocardium, vasculature, and coagulation cascade, related to the proinflammatory and prothrombotic effects of the virus, leading to an increased risk of myocardial infarction, stroke, deep venous thrombosis, and pulmonary emboli within the first 2 to 4 weeks of contracting the disease. Patients with preexistent cardiovascular disease and/or cardiovascular risk factors, such as hypertension and diabetes, are particularly susceptible to suffer complications f...
Source: Cardiology Clinics - May 11, 2022 Category: Cardiology Authors: Timothy D. Henry, Santiago Garcia Tags: Preface Source Type: research

Acute Occupational and Physical Therapy for COVID-19 Patients: A Retrospective Cohort Study
In March 2020, the World Health Organization (WHO) declared the novel coronavirus strain SARS-CoV2 (the virus causing COVID-19) a global pandemic.24 The severity of illness in those exhibiting symptoms ranges from mild (cough, shortness of breath, fatigue) to severe (acute respiratory distress syndrome (ARDS), thrombosis, stroke, and death).4,11 Patients have also acquired acute polyradiculoneuritis (Guillain Barre syndrome) at a disproportionately high rate, contributing to functional limitations that require specialized and intensive rehabilitation.
Source: Archives of Physical Medicine and Rehabilitation - July 31, 2022 Category: Rehabilitation Authors: Katie Coakley, Laura Friedman, Kaitlyn McLoughlin, Amy Wozniak, Paul Hutchison Tags: Original Research Source Type: research

An acute lower limb ischemia revealing a covid-19 infection: A case report
CONCLUSION: The coagulopathy responsible for venous and arterial thrombosis is a well-established complication of COVID-19. Arterial thromboembolic complications can be either stroke, acute coronary syndrome or peripheral acute ischemia. Therefore, patients with covid19 should be monitored more closely for thromboembolic complications.PMID:35999833 | PMC:PMC9389520 | DOI:10.1016/j.amsu.2022.104445
Source: Annals of Medicine - August 24, 2022 Category: Internal Medicine Authors: Rim El Mesnaoui Soumaila Nikiema Desire Massimbo Abbes El Mesnaoui Source Type: research

Neurological consequences of COVID-19
Pharmacol Rep. 2022 Sep 30. doi: 10.1007/s43440-022-00424-6. Online ahead of print.ABSTRACTIn December 2019, cases of pneumonia caused by infection with the previously unknown severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), leading to coronavirus disease 2019 (COVID-19), were identified. Typical manifestations of COVID-19 are fever, cough, fatigue and dyspnoea. Initially, it was thought that the mechanism of action of SARS-CoV-2 was only associated with respiratory tract invasion, but it was later revealed that the infection might involve many other organs and systems, including the central and peripheral ner...
Source: Pharmacological Reports - September 30, 2022 Category: Drugs & Pharmacology Authors: Waldemar Brola Maciej Wilski Source Type: research