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Geniposide Alleviates Glucocorticoid-Induced Inhibition of Osteogenic Differentiation in MC3T3-E1 Cells by ERK Pathway
Conclusion In summary, we demonstrated that geniposide alleviated GC-induced osteogenic suppression in MC3T3-E1 cells. The effects of geniposide were at least partially associated with activating ERK signaling pathway via GLP-1 receptor. Geniposide might be a potential therapeutic agent for protection against GC-induced osteoporosis. Author Contributions BX, DX, CZ, and LW participated in research design. BX, JW, YL, XW, and ZZ conducted the experiments. BX, DX, and LW contributed new reagents or analytic tools and wrote or contributed to the writing of the manuscript. BX, JW, CZ, and DX performed the data analysis. Fu...
Source: Frontiers in Pharmacology - April 17, 2019 Category: Drugs & Pharmacology Source Type: research

The 2017 hormone therapy position statement of The North American Menopause Society
The 2017 Hormone Therapy Position Statement of The North American Menopause Society (NAMS) updates the 2012 Hormone Therapy Position Statement of The North American Menopause Society and identifies future research needs. An Advisory Panel of clinicians and researchers expert in the field of women's health and menopause was recruited by NAMS to review the 2012 Position Statement, evaluate new literature, assess the evidence, and reach consensus on recommendations, using the level of evidence to identify the strength of recommendations and the quality of the evidence. The Panel's recommendations were reviewed and approved by...
Source: Menopause - October 25, 2018 Category: OBGYN Tags: Commemorative Papers Source Type: research

7 Foot Problems That Can Be Serious
If you want to know the state of your health, try looking down. “There’s no question it’s extremely important that people pay attention to their feet,” says Terry Philbin, D.O., spokesperson for the American Academy of Orthopedic Surgeons (AAOS) and a foot and ankle specialist at the Orthopedic Foot and Ankle Center in Westerville, Ohio. The condition of your feet can give you clues to a host of medical issues, such as diabetes, arthritis, and even heart disease. Read on to find out what to look for and what it may mean. 1. Pain “There’s no pain that should be ignored,” says Jane ...
Source: Healthy Living - The Huffington Post - November 12, 2016 Category: Consumer Health News Source Type: news

Osteoporosis in patients with stroke: A cross-sectional study
Snezana Tomasevic-Todorovic, Dusica Simic-Panic, Aleksandar Knezevic, Cila Demesi-Drljan, Dusan Maric, Fahad HannaAnnals of Indian Academy of Neurology 2016 19(2):286-288
Source: Annals of Indian Academy of Neurology - May 11, 2016 Category: Neurology Authors: Snezana Tomasevic-TodorovicDusica Simic-PanicAleksandar KnezevicCila Demesi-DrljanDusan MaricFahad Hanna Source Type: research

Practice Paper of the Academy of Nutrition and Dietetics Abstract: Nutrition and Women's Health
Abstract: Women account for 51% of the US population. Currently, cardiovascular disease (CVD) is the leading cause of death in women, followed by cancer and stroke. Breast cancer, while associated with lower mortality than most other cancers, is the leading cause of cancer-related morbidity in women. Osteoporosis also threatens women, particularly after menopause. Importantly, each of these diagnoses in aging women share a commonality in that lifestyle choices, including diet, play a primary role in prevention and treatment of these diseases. This practice paper provides a synopsis of current dietary recommendations for CV...
Source: Journal of the American Dietetic Association - October 22, 2013 Category: Nutrition Authors: Jean T. Cox, Karen Chapman-Novakofski, Cynthia A. Thomson Tags: Practice Paper Source Type: research

Lack of parental warmth, abuse in childhood linked to multiple health risks in adulthood
This study was also supported by the MacArthur Research Network on Socioeconomic Status and Health through grants from the John D. and Catherine T. MacArthur Foundation, and by grant T32-MH19925 and the Cousins Center for Psychoneuroimmunology at the UCLA.   The UCLA Cousins Center for Psychoneuroimmunology encompasses an interdisciplinary network of scientists working to advance the understanding of psychoneuroimmunology by linking basic and clinical research programs and by translating findings into clinical practice. The center is affiliated with the Semel Institute for Neuroscience and Human Behavior and the David...
Source: UCLA Newsroom: Health Sciences - October 1, 2013 Category: Universities & Medical Training Source Type: news