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Condition: Hypertension

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Total 16251 results found since Jan 2013.

Who needs to be screened for primary aldosteronism?
J Formos Med Assoc. 2023 Aug 24:S0929-6646(23)00335-2. doi: 10.1016/j.jfma.2023.08.021. Online ahead of print.ABSTRACTThe prevalence of patients with primary aldosteronism (PA) is about 5%-15% in hypertensive patients, and it is common cause of secondary hypertension in clinical practice. Two major causes of PA are noted, namely bilateral adrenal hyperplasia and aldosterone-producing adenoma, and the general diagnosis is based on three steps: (1) screening, (2) confirmatory testing, and (3) subtype differentiation (Figure 1). The recommendation for screening patients is at an increased risk of PA, here we focus on which pa...
Source: J Formos Med Assoc - August 26, 2023 Category: General Medicine Authors: Wei-Chieh Huang Feng-Hsuan Liu Hao-Min Cheng Yi-Chun Tsai Yen-Ta Huang Tai-Shuan Lai Yen-Hung Lin Vin-Cent Wu Hsien-Li Kao Charles Jia-Yin Hou Kwan-Dun Wu Szu-Tah Chen Leay Kiaw Er Source Type: research

Long-term exposure to ambient ozone and cardiovascular diseases: evidence from two national cohort studies in China
CONCLUSIONS: Long-term exposure to MDA8 O3 may increase the incidence of CVD. Therefore, the policies that control O3 and related precursors are persistently needed.PMID:37625570 | DOI:10.1016/j.jare.2023.08.010
Source: Adv Data - August 25, 2023 Category: Epidemiology Authors: Shuru Liang Yumeng Chen Xiaoli Sun Xiaomei Dong Guanhao He Yudong Pu Jingjie Fan Xinqi Zhong Zhiqing Chen Ziqiang Lin Wenjun Ma Tao Liu Source Type: research

Clinical characteristics and predictors for in-hospital mortality in adult COVID-19 patients: A retrospective single center cohort study in Vilnius, Lithuania
ConclusionsAge, congestive heart failure, obesity, COPD, prior stroke, and increased concentration of urea, LDH, CRP, IL-6, troponin I, ALT to AST ratio were identified to be the predictors for in-hospital mortality of COVID-19 patients.
Source: PLoS One - August 25, 2023 Category: Biomedical Science Authors: Ieva Kubiliute Source Type: research

Cardiovascular Complications in Pregnancy
AbstractPurpose of reviewWe review the epidemiology, risk factors, presentation, pathophysiology, diagnosis, peripartum management, and postpartum follow-up of chronic hypertension, hyperlipidemia, acute myocardial infarction, stroke, heart failure, pulmonary embolism, and atrial fibrillation.Recent findingsWe discuss pathophysiology and evidence-based management for chronic hypertension, hyperlipidemia, acute myocardial infarction, stroke, heart failure, pulmonary embolism, and atrial fibrillation.SummaryIt is essential for providers and patients to understand how cardiovascular diseases cause complications in pregnancy a...
Source: Current Treatment Options in Cardiovascular Medicine - August 25, 2023 Category: Cardiology Source Type: research

Alcohol Consumption and Cerebral Small- and Large-Vessel Diseases: A Mendelian Randomization Analysis
CONCLUSIONS: Our findings suggest a positive association of alcohol consumption with risk of cerebral SVDs and its inverse association with risk of large-vessel disease through intermediaries, such as hypertension or low-density lipoprotein cholesterol. These findings provide insight into potential causal mechanisms linking alcohol consumption with stroke risk.PMID:37612092 | DOI:10.5551/jat.64222
Source: Journal of Atherosclerosis and Thrombosis - August 23, 2023 Category: Cardiology Authors: Takashi Hisamatsu Yasuharu Tabara Aya Kadota Sayuki Torii Keiko Kondo Yuichiro Yano Akihiko Shiino Kazuhiko Nozaki Tomonori Okamura Hirotsugu Ueshima Katsuyuki Miura SESSA Research Group Source Type: research

Trimethylamine N-Oxide and White Matter Hyperintensity Volume Among Patients With Acute Ischemic Stroke
CONCLUSIONS AND RELEVANCE: In this observational study, TMAO was associated with cerebral small vessel disease determined by WMHV and acute lacunar infarction. The association was independent of traditional vascular risk factors.PMID:37610752 | PMC:PMC10448304 | DOI:10.1001/jamanetworkopen.2023.30446
Source: Atherosclerosis - August 23, 2023 Category: Cardiology Authors: Naruchorn Kijpaisalratana Zsuzsanna Ament Matthew B Bevers Varun M Bhave Ana-Lucia Garcia Guarniz Catharine A Couch M Ryan Irvin W Taylor Kimberly Source Type: research

Alcohol Consumption and Cerebral Small- and Large-Vessel Diseases: A Mendelian Randomization Analysis
CONCLUSIONS: Our findings suggest a positive association of alcohol consumption with risk of cerebral SVDs and its inverse association with risk of large-vessel disease through intermediaries, such as hypertension or low-density lipoprotein cholesterol. These findings provide insight into potential causal mechanisms linking alcohol consumption with stroke risk.PMID:37612092 | DOI:10.5551/jat.64222
Source: Journal of Atherosclerosis and Thrombosis - August 23, 2023 Category: Cardiology Authors: Takashi Hisamatsu Yasuharu Tabara Aya Kadota Sayuki Torii Keiko Kondo Yuichiro Yano Akihiko Shiino Kazuhiko Nozaki Tomonori Okamura Hirotsugu Ueshima Katsuyuki Miura SESSA Research Group Source Type: research

CYP2C19 Loss-of-Function Variants Associated with Long-term Ischemic Stroke Events During Clopidogrel Treatment in the Chinese Population
This study aims to determine whether CYP2C19 loss-of-function (LoF) variants were associated with long-term ischemic stroke risk in Chinese primary care patients treated with clopidogrel. Patients treated with clopidogrel were ascertained from a Chinese Electronic Medical Record linked with biobank for a retrospective cohort study. Their medical information was examined for the period from January 2018 to December 2021. Two CYP2C19 major loss of function variants (*2:rs4244285, *3: rs4986893) were genotyped. The clinical outcome was ischemic stroke event. Cox regression analysis was used to evaluate the association between...
Source: Clinical Pharmacology and Therapeutics - August 22, 2023 Category: Drugs & Pharmacology Authors: Peng Wu Ziqing Liu Zijian Tian Benrui Wu Jian Shao Qian Li Zhaoxu Geng Ying Pan Ke Lu Qiang Wang Tao Xu Kaixin Zhou Source Type: research

Vertebrobasilar Artery Calcification as a Risk Factor for the Development of Stroke: Case-Control Study From a Tertiary Care Center, Southern India
Conclusion The presence of higher grades of calcifications in the vertebrobasilar arteries is a major risk factor for stroke. Hence, its presence in asymptomatic individuals needs to be taken as a warning sign for the development of stroke.PMID:37605701 | PMC:PMC10440145 | DOI:10.7759/cureus.42196
Source: Atherosclerosis - August 22, 2023 Category: Cardiology Authors: Kibballi M Adarsh H Pavithra Valiyapalathingal Abdul Rasheed Source Type: research

Evaluation of Large-Scale Proteomics for Prediction of Cardiovascular Events
CONCLUSIONS AND RELEVANCE: A protein risk score was significantly associated with ASCVD events in primary and secondary event populations. When added to clinical risk factors, the protein risk score and polygenic risk score both provided statistically significant but modest improvement in discrimination.PMID:37606673 | DOI:10.1001/jama.2023.13258
Source: Atherosclerosis - August 22, 2023 Category: Cardiology Authors: Hannes Helgason Thjodbjorg Eiriksdottir Magnus O Ulfarsson Abhishek Choudhary Sigrun H Lund Erna V Ivarsdottir Grimur Hjorleifsson Eldjarn Gudmundur Einarsson Egil Ferkingstad Kristjan H S Moore Narimon Honarpour Thomas Liu Huei Wang Thomas Hucko Marc S S Source Type: research

Vertebrobasilar Artery Calcification as a Risk Factor for the Development of Stroke: Case-Control Study From a Tertiary Care Center, Southern India
Conclusion The presence of higher grades of calcifications in the vertebrobasilar arteries is a major risk factor for stroke. Hence, its presence in asymptomatic individuals needs to be taken as a warning sign for the development of stroke.PMID:37605701 | PMC:PMC10440145 | DOI:10.7759/cureus.42196
Source: Atherosclerosis - August 22, 2023 Category: Cardiology Authors: Kibballi M Adarsh H Pavithra Valiyapalathingal Abdul Rasheed Source Type: research