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Source: Stroke
Condition: Hemorrhagic Stroke

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Total 995 results found since Jan 2013.

Cost-Effectiveness of Thrombectomy in Patients With Acute Ischemic Stroke Clinical Sciences
Conclusions—Based on randomized trial data, this study demonstrates that IVMT used to treat acute ischemic stroke is cost-effective when compared with IVT alone.Clinical Trial Registration—URL: http://www.clinicaltrials.gov. Unique identifier: NCT01062698.
Source: Stroke - September 25, 2017 Category: Neurology Authors: Hamza Achit, Marc Soudant, Kossar Hosseini, Aurelie Bannay, Jonathan Epstein, Serge Bracard, Francis Guillemin Tags: Cost-Effectiveness, Ischemic Stroke Original Contributions Source Type: research

Intracerebral Hemorrhage and Outcome After Thrombolysis in Stroke Patients Using Selective Serotonin-Reuptake Inhibitors Clinical Sciences
Background and Purpose—Selective serotonin-reuptake inhibitors (SSRIs) impair platelet function and have been linked to a higher risk of spontaneous intracerebral hemorrhage—an association that may be augmented by oral anticoagulants (OAC). We aimed to assess whether preadmission treatment with SSRIs in patients with acute ischemic stroke is associated with post-thrombolysis symptomatic intracerebral hemorrhage (sICH) and functional outcome.Methods—A multicenter retrospective analysis was conducted in prospective registries of patients treated by thrombolysis within 4.5 hours of stroke onset. The association between ...
Source: Stroke - November 27, 2017 Category: Neurology Authors: Jan F. Scheitz, Guillaume Turc, Linda Kuȷala, Alexandros A. Polymeris, Mirȷam R. Heldner, Thomas P. Zonneveld, Hebun Erdur, Sami Curtze, Christopher Traenka, Celine Breniere, Roland Wiest, Andrea Rocco, Gerli Sibolt, Henrik Gensicke, Matthia Tags: Complications, Ischemic Stroke Original Contributions Source Type: research

Echocardiographic Risk Factors for Stroke and Outcomes in Patients With Atrial Fibrillation Anticoagulated With Apixaban or Warfarin Clinical Sciences
Conclusions—In anticoagulated patients with atrial fibrillation and risk factors for stroke, echocardiographic findings do not seem to add to the risk of thromboembolic events.Clinical Trial Registration—URL: http://www.clinicaltrials.gov. Unique identifier: NCT00412984.
Source: Stroke - November 27, 2017 Category: Neurology Authors: Dragos Vinereanu, Renato D. Lopes, Hillary Mulder, Bernard J. Gersh, Michael Hanna, Pedro G.M. de Barros e Silva, Dan Atar, Lars Wallentin, Christopher B. Granger, John H. Alexander Tags: Arrhythmias, Echocardiography, Intracranial Hemorrhage, Ischemic Stroke Original Contributions Source Type: research

Contact Aspiration Versus Stent Retriever in Patients With Acute Ischemic Stroke With M2 Occlusion in the ASTER Randomized Trial (Contact Aspiration Versus Stent Retriever for Successful Revascularization) Brief Report
Conclusions—First-line mechanical thrombectomy with CA compared with SR did not result in an increased successful revascularization rate in patients with acute stroke with isolated M2 occlusion.
Source: Stroke - January 22, 2018 Category: Neurology Authors: Benjamin Gory, Bertrand Lapergue, Raphael Blanc, Julien Labreuche, Malek Ben Machaa, Alain Duhamel, Gautier Marnat, Suzana Saleme, Vincent Costalat, Serge Bracard, Hubert Desal, Mikael Mazighi, Arturo Consoli, Michel Piotin, for the ASTER Trial Investiga Tags: Revascularization, Stent, Treatment, Complications, Ischemic Stroke Brief Reports Source Type: research

Childhood Stature and Growth in Relation to First Ischemic Stroke or Intracerebral Hemorrhage Clinical Sciences
Conclusions—Short stature at 7 to 13 years is significantly associated with increased risks of IS in both sexes and with ICH in men. Growth during this period of childhood is not significantly associated with either of these stroke subtypes, suggesting that underlying mechanisms linking height with risks of stroke may exert their influence already by early childhood.
Source: Stroke - February 26, 2018 Category: Neurology Authors: Line Klingen Gȷarde, Thomas Clement Truelsen, Jennifer Lyn Baker Tags: Etiology, Epidemiology, Pediatrics, Intracranial Hemorrhage, Ischemic Stroke Original Contributions Source Type: research

Long-Term Risk of Hemorrhagic Stroke in Young Patients With Congenital Heart Disease Clinical Sciences
Conclusions—The relative risk of hemorrhagic stroke among children and young adults with CHD was almost 8× higher than that of matched controls from the general population, although the absolute risk was low. The highest risk of ICH and SAH occurred in patients with severe nonconotruncal defects and coarctation of the aorta.
Source: Stroke - April 23, 2018 Category: Neurology Authors: Kok Wai Giang, Zacharias Mandalenakis, Mikael Dellborg, Georgios Lappas, Peter Eriksson, Per-Olof Hansson, Annika Rosengren Tags: Epidemiology, Cerebrovascular Disease/Stroke, Cerebrovascular Malformations, Intracranial Hemorrhage Original Contributions Source Type: research

Impact of Smoking on Clinical Outcome and Recanalization After Intravenous Thrombolysis for Stroke Clinical Sciences
Conclusions—Our study suggests that good outcome in smokers is mainly related to differences in baseline characteristics and not to biological effects of smoking. The higher recanalization rates in smokers, however, call for further studies.
Source: Stroke - April 23, 2018 Category: Neurology Authors: Rebekka Kurmann, Stefan T. Engelter, Patrik Michel, Andreas R. Luft, Susanne Wegener, Meret Branscheidt, Elissavet Eskioglou, Gaia Sirimarco, Philippe A. Lyrer, Henrik Gensicke, Thomas Horvath, Urs Fischer, Marcel Arnold, Hakan Sarikaya Tags: Cerebrovascular Disease/Stroke, Ischemic Stroke Original Contributions Source Type: research

Human Neural Stem Cell Extracellular Vesicles Improve Recovery in a Porcine Model of Ischemic Stroke Basic Sciences
Conclusions—This study demonstrated for the first time that in a large animal model novel NSC EVs significantly improved neural tissue preservation and functional levels post-MCAO, suggesting NSC EVs may be a paradigm changing stroke therapeutic.
Source: Stroke - April 23, 2018 Category: Neurology Authors: Robin L. Webb, Erin E. Kaiser, Brian J. Jurgielewicz, Samantha Spellicy, Shelley L. Scoville, Tyler A. Thompson, Raymond L. Swetenburg, David C. Hess, Franklin D. West, Steven L. Stice Tags: Animal Models of Human Disease, Basic Science Research, Translational Studies, Treatment, Ischemic Stroke Original Contributions Source Type: research

Antiplatelet Treatment After Transient Ischemic Attack and Ischemic Stroke in Patients With Cerebral Microbleeds in 2 Large Cohorts and an Updated Systematic Review Clinical Sciences
Background and Purpose—In patients with transient ischemic attack/ischemic stroke, microbleed burden predicts intracerebral hemorrhage (ICH), and ischemic stroke, but implications for antiplatelet treatment are uncertain. Previous cohort studies have had insufficient follow-up to assess the time course of risks, have not stratified risks by antithrombotic use, and have not reported extracranial bleeds or functional outcome of ICH versus ischemic stroke.Methods—In 2 independent prospective cohorts with transient ischemic attack/ischemic stroke (Oxford Vascular Study/mainly white; University of Hong Kong/mainly Chinese),...
Source: Stroke - May 25, 2018 Category: Neurology Authors: Kui Kai Lau, Caroline E. Lovelock, Linxin Li, Michela Simoni, Sergei Gutnikov, Wilhelm Kuker, Henry Ka Fung Mak, Peter M. Rothwell Tags: Magnetic Resonance Imaging (MRI), Intracranial Hemorrhage, Ischemic Stroke, Transient Ischemic Attack (TIA) Original Contributions Source Type: research

Stroke-Related Early Tracheostomy Versus Prolonged Orotracheal Intubation in Neurocritical Care Trial (SETPOINT): A Randomized Pilot Trial Original Contributions
Conclusions— Early tracheostomy in ventilated intensive care stroke patients is feasible, and safe, and presumably reduces sedation need. Whether the suggested benefits in mortality and outcome truly exist has to be determined by a larger multicenter trial. Clinical Trial Registration— http://www.clinicaltrials.gov. Unique identifier: NCT01261091.
Source: Stroke - December 24, 2012 Category: Neurology Authors: Bosel, J., Schiller, P., Hook, Y., Andes, M., Neumann, J.-O., Poli, S., Amiri, H., Schonenberger, S., Peng, Z., Unterberg, A., Hacke, W., Steiner, T. Tags: Other Treatment, Acute Cerebral Hemorrhage, Acute Cerebral Infarction, Cerebral Aneurysm, AVM, & Subarachnoid hemorrhage, Other Stroke Treatment - Surgical Original Contributions Source Type: research

Subarachnoid Hemorrhage in a Multimodal Approach Heavily Weighted Toward Mechanical Thrombectomy With Solitaire Stent in Acute Stroke Original Contributions
Conclusions— SAH on post-therapeutic computerized tomography scans were not uncommon after primary mechanical thrombectomy with a Solitaire stent, but they seemed to be benign. Rescue angioplasty and unidentified, small vessel ruptures due to mechanical stretch during stent retrieval might give rise to these lesions.
Source: Stroke - January 18, 2013 Category: Neurology Authors: Yoon, W., Jung, M. Y., Jung, S. H., Park, M. S., Kim, J. T., Kang, H. K. Tags: Acute Cerebral Infarction, Emergency treatment of Stroke, Computerized tomography and Magnetic Resonance Imaging, Intracerebral Hemorrhage Original Contributions Source Type: research

High-density Lipoprotein-based Therapy Reduces the Hemorrhagic Complications Associated With Tissue Plasminogen Activator Treatment in Experimental Stroke Clinical Sciences
Conclusions— HDL injection decreased tPA-induced hemorrhagic transformation in rat models of MCAO. Both in vivo and in vitro results support the vasculoprotective action of HDLs on BBB under ischemic conditions.
Source: Stroke - February 25, 2013 Category: Neurology Authors: Lapergue, B., Dang, B. Q., Desilles, J.-P., Ortiz-Munoz, G., Delbosc, S., Loyau, S., Louedec, L., Couraud, P.-O., Mazighi, M., Michel, J.-B., Meilhac, O., Amarenco, P. Tags: Lipids, Animal models of human disease, Acute Cerebral Infarction, Emergency treatment of Stroke, Neuroprotectors, Thrombolysis, Endothelium/vascular type/nitric oxide Clinical Sciences Source Type: research

Systolic Blood Pressure After Intravenous Antihypertensive Treatment and Clinical Outcomes in Hyperacute Intracerebral Hemorrhage: The Stroke Acute Management With Urgent Risk-Factor Assessment and Improvement-Intracerebral Hemorrhage Study Clinical Sciences
Conclusions— High achieved SBP after standardized antihypertensive therapy in hyperacute intracerebral hemorrhage was independently associated with poor clinical outcomes. Aggressive antihypertensive treatment may ameliorate clinical outcomes.
Source: Stroke - June 24, 2013 Category: Neurology Authors: Sakamoto, Y., Koga, M., Yamagami, H., Okuda, S., Okada, Y., Kimura, K., Shiokawa, Y., Nakagawara, J., Furui, E., Hasegawa, Y., Kario, K., Arihiro, S., Sato, S., Kobayashi, J., Tanaka, E., Nagatsuka, K., Minematsu, K., Toyoda, K., for the SAMURAI Study Inv Tags: Cerebrovascular disease/stroke, CT and MRI, Acute Cerebral Hemorrhage, Other Stroke Treatment - Medical Clinical Sciences Source Type: research

Prospective, Multicenter, Single-Arm Study of Mechanical Thrombectomy Using Solitaire Flow Restoration in Acute Ischemic Stroke Clinical Sciences
Conclusions— In this single-arm study, treatment with the Solitaire Flow Restoration device in intracranial anterior circulation occlusions results in high rates of revascularization, low risk of clinically relevant procedural complications, and good clinical outcomes in combination with low mortality at 90 days. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT01327989.
Source: Stroke - September 23, 2013 Category: Neurology Authors: Pereira, V. M., Gralla, J., Davalos, A., Bonafe, A., Castano, C., Chapot, R., Liebeskind, D. S., Nogueira, R. G., Arnold, M., Sztajzel, R., Liebig, T., Goyal, M., Besselmann, M., Moreno, A., Schroth, G. Tags: Emergency treatment of Stroke Clinical Sciences Source Type: research

THRIVE Score Predicts Ischemic Stroke Outcomes and Thrombolytic Hemorrhage Risk in VISTA Clinical Sciences
Conclusions— The THRIVE score is a simple-to-use tool to predict clinical outcome, mortality, and risk of hemorrhage after thrombolysis in patients with ischemic stroke. Despite its simplicity, the THRIVE score performs better than several other outcome prediction tools. A free Web calculator for the THRIVE score is available at http://www.thrivescore.org.
Source: Stroke - November 25, 2013 Category: Neurology Authors: Flint, A. C., Faigeles, B. S., Cullen, S. P., Kamel, H., Rao, V. A., Gupta, R., Smith, W. S., Bath, P. M., Donnan, G. A., on behalf of the VISTA Collaboration, VISTA Steering Committee (VISTA-Acute) members, Lees, Alexandrov, Bath, Bluhmki, Bornstein, Cla Tags: Emergency treatment of Stroke Clinical Sciences Source Type: research