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Source: Stroke
Condition: Hemorrhagic Stroke

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Total 995 results found since Jan 2013.

Standard-Dose Intravenous Tissue-Type Plasminogen Activator for Stroke Is Better Than Low Doses Clinical Sciences
Conclusions— Our study suggests that standard-dose intravenous tPA for stroke had more favorable outcome without increasing the risk of symptomatic intracranial hemorrhage than low-dose tPA. For Asian people, 0.9 mg/kg should be the optimal dose of tPA to treat acute ischemic stroke.
Source: Stroke - July 28, 2014 Category: Neurology Authors: Liao, X., Wang, Y., Pan, Y., Wang, C., Zhao, X., Wang, D. Z., Wang, C., Liu, L., Wang, Y., on behalf of the Thrombolysis Implementation and Monitor of Acute Ischemic Stroke in China Investigators Tags: Acute Cerebral Infarction, Thrombolysis Clinical Sciences Source Type: research

Optimizating Clot Retrieval in Acute Stroke: The Push and Fluff Technique for Closed-Cell Stentrievers Clinical Sciences
Conclusions— The PFT is safe and leads to optimization of wall apposition and cell size/configuration, resulting in higher chances of first-pass reperfusion, lower number of passes, and better rates of complete reperfusion.
Source: Stroke - September 28, 2015 Category: Neurology Authors: Haussen, D. C., Rebello, L. C., Nogueira, R. G. Tags: Emergency treatment of Stroke, Other imaging, Other Stroke Treatment - Surgical Clinical Sciences Source Type: research

Nonaspirin Nonsteroidal Anti-Inflammatory Drugs and Risk of Hemorrhagic Stroke: A Systematic Review and Meta-Analysis of Observational Studies Clinical Sciences
Conclusions— Overall, the use of NSAIDs is not associated with an increased risk of hemorrhagic stroke, although this risk was modestly significantly elevated in diclofenac and meloxicam users.
Source: Stroke - January 25, 2016 Category: Neurology Authors: Ungprasert, P., Matteson, E. L., Thongprayoon, C. Tags: Risk Factors, Cerebrovascular Disease/Stroke, Intracranial Hemorrhage Clinical Sciences Source Type: research

Streamlined Hyperacute Magnetic Resonance Imaging Protocol Identifies Tissue-Type Plasminogen Activator-Eligible Stroke Patients When Clinical Impression Is Stroke Mimic Clinical Sciences
Conclusions— A streamlined hMRI protocol permitted tPA administration to a small, but significant, subset of AIS patients initially considered to have SM.
Source: Stroke - March 27, 2016 Category: Neurology Authors: Goyal, M. S., Hoff, B. G., Williams, J., Khoury, N., Wiesehan, R., Heitsch, L., Panagos, P., Vo, K. D., Benzinger, T., Derdeyn, C. P., Lee, J.-M., Ford, A. L. Tags: Magnetic Resonance Imaging (MRI), Cerebrovascular Disease/Stroke, Ischemic Stroke Clinical Sciences Source Type: research

Direct Mechanical Intervention Versus Combined Intravenous and Mechanical Intervention in Large Artery Anterior Circulation Stroke: A Matched-Pairs Analysis Clinical Sciences
Conclusions— In patients with large anterior circulation stroke, direct mechanical intervention seems to be equally effective as bridging thrombolysis. A randomized trial comparing direct MT with bridging therapy is warranted.
Source: Stroke - March 27, 2016 Category: Neurology Authors: Broeg-Morvay, A., Mordasini, P., Bernasconi, C., Buhlmann, M., Pult, F., Arnold, M., Schroth, G., Jung, S., Mattle, H. P., Gralla, J., Fischer, U. Tags: Cardiopulmonary Resuscitation and Emergency Cardiac Care, Treatment, Ischemic Stroke Clinical Sciences Source Type: research

ALIAS (Albumin in Acute Ischemic Stroke) Trials: Analysis of the Combined Data From Parts 1 and 2 Clinical Sciences
Conclusions— Treatment with intravenous albumin 25% at 2 g/kg was not associated with improved outcome at 90 days and was associated with increased rates of intracerebral hemorrhage and pulmonary edema. Clinical Trial Registration— URL: https://www.clinicaltrials.gov. Unique identifier: NCT00235495.
Source: Stroke - August 21, 2016 Category: Neurology Authors: Martin, R. H., Yeatts, S. D., Hill, M. D., Moy, C. S., Ginsberg, M. D., Palesch, Y. Y., for the ALIAS Parts 1 and 2 and NETT Investigators Tags: Clinical Studies, Ischemic Stroke Clinical Sciences Source Type: research

Influence of Device Choice on the Effect of Intra-Arterial Treatment for Acute Ischemic Stroke in MR CLEAN (Multicenter Randomized Clinical Trial of Endovascular Treatment for Acute Ischemic Stroke in the Netherlands) Clinical Sciences
Conclusions— We found no evidence for a differential effect of thrombectomy for acute ischemic stroke by type of stent. Clinical Trial Registration— URL: http://www.isrctn.com. Unique identifier: ISRCTN10888758.
Source: Stroke - September 25, 2016 Category: Neurology Authors: Dippel, D. W., Majoie, C. B., Roos, Y. B., van der Lugt, A., van Oostenbrugge, R. J., van Zwam, W. H., Lingsma, H. F., Koudstaal, P. J., Treurniet, K. M., van den Berg, L. A., Beumer, D., Fransen, P. S., Berkhemer, O. A., for the MR CLEAN Investigators Tags: Ischemic Stroke Clinical Sciences Source Type: research

Safety and Preliminary Efficacy of Early Tirofiban Treatment After Alteplase in Acute Ischemic Stroke Patients Brief Reports
Conclusions— Intravenous tirofiban immediately after alteplase seems to be safe and potentially more effective when compared with alteplase alone for selected stroke patients. Clinical Trial Registration— URL: http://www.chictr.org.cn/. Unique identifier: ChiCTR-TRC-14004630.
Source: Stroke - September 25, 2016 Category: Neurology Authors: Li, W., Lin, L., Zhang, M., Wu, Y., Liu, C., Li, X., Huang, S., Liang, C., Wang, Y., Chen, J., Feng, W. Tags: Pharmacology, Treatment, Ischemic Stroke Brief Reports Source Type: research

Rheumatic Mitral Valve Disease Is Associated With Worse Outcomes in Stroke Clinical Sciences
We examined the association between RMVD and both serious and common cardiovascular and noncardiovascular (respiratory and infective) complications in a cohort of hospitalized stroke patients based in Thailand. Factors associated with in-hospital mortality were also explored. Data were obtained from a National Insurance Database. All hospitalized strokes between October 1, 2004, and January 31, 2013, were included in the current study. Characteristics and outcomes were compared for RMVD and non-RMVD patients. Logistic regression, propensity score matching, and multivariate models were used to assess study outcomes.Resultsâ...
Source: Stroke - October 23, 2016 Category: Neurology Authors: Wood, A. D., Mannu, G. S., Clark, A. B., Tiamkao, S., Kongbunkiat, K., Bettencourt-Silva, J. H., Sawanyawisuth, K., Kasemsap, N., Barlas, R. S., Mamas, M., Myint, P. K. Tags: Rheumatic Heart Disease, Valvular Heart Disease, Complications, Mortality/Survival, Cerebrovascular Disease/Stroke Original Contributions Source Type: research

Automated Software System to Promote Anticoagulation and Reduce Stroke Risk Brief Report
Conclusions—No significant change in OAC prescribing occurred. A greater rate of diagnosis of transient ischemic attack (possibly because of improved detection or overdiagnosis) was associated with a reduction (of borderline significance) in stroke and hemorrhage over 12 months.Clinical Trial Registration—URL: http://www.isrctn.com. Unique Identifier: ISRCTN55722437.
Source: Stroke - February 26, 2017 Category: Neurology Authors: Tim A. Holt, Andrew Dalton, Tom Marshall, Matthew Fay, Nadeem Qureshi, Susan Kirkpatrick, Jenny Hislop, Daniel Lasserson, Karen Kearley, Jill Mollison, Ly-Mee Yu, F.D. Richard Hobbs, David Fitzmaurice Tags: Atrial Fibrillation, Anticoagulants, Health Services, Ischemic Stroke Brief Reports Source Type: research

Successful Reperfusion With Mechanical Thrombectomy Is Associated With Reduced Disability and Mortality in Patients With Pretreatment Diffusion-Weighted Imaging-Alberta Stroke Program Early Computed Tomography Score
Background and Purpose—In acute ischemic stroke patients, diffusion-weighted imaging (DWI)–Alberta Stroke Program Early Computed Tomography Score (ASPECTS) is correlated with infarct volume and is an independent factor of functional outcome. Patients with pretreatment DWI-ASPECTS ≤6 were excluded or under-represented in the recent randomized mechanical thrombectomy trials. Our aim was to assess the impact of reperfusion in pretreatment DWI-ASPECTS ≤6 patients treated with mechanical thrombectomy.Methods—We analyzed data collected between January 2012 and August 2015 in a bicentric prospective clinical registry of...
Source: Stroke - March 27, 2017 Category: Neurology Authors: Jean–Philippe Desilles, Arthuro Consoli, Hocine Redȷem, Oguzhan Coskun, Gabriele Ciccio, Stanislas Smaȷda, Julien Labreuche, Cristian Preda, Clara Ruiz Guerrero, Jean–Pierre Decroix, Georges Rodesch, Mikael Mazighi, Raphael Blanc Tags: Magnetic Resonance Imaging (MRI), Revascularization, Cerebrovascular Disease/Stroke, Cerebrovascular Procedures, Ischemic Stroke Original Contributions Source Type: research

PAIS 2 (Paracetamol Acetaminophen in Stroke 2) Clinical Sciences
Conclusions—Treatment with high-dose paracetamol seemed to be safe. The effect of high-dose paracetamol on functional outcome remains uncertain. Therefore, a large trial of early treatment with high-dose paracetamol is still needed.Clinical Trial Registration—URL: http://www.trialregister.nl. Unique identifier: NTR2365.
Source: Stroke - March 27, 2017 Category: Neurology Authors: Inger R. de Ridder, Heleen M. den Hertog, H. Maarten A. van Gemert, A.H.C.M.L. (Tobien) Schreuder, Annemieke Ruitenberg, E. (Lisette) Maasland, Ritu Saxena, Jordie H. van Tuijl, Ben P.W. Jansen, Renske M. Van den Berg-Vos, Frederique Vermeij, Peter J. Kou Tags: Pharmacology, Meta Analysis, Quality and Outcomes, Intracranial Hemorrhage, Ischemic Stroke Original Contributions Source Type: research

Clinical Significance of Wall Changes After Recanalization Therapy in Acute Stroke Brief Report
Conclusions—The use of high-resolution vessel wall imaging after successful recanalization can provide information about postrecanalization arterial wall changes and clinical outcomes.
Source: Stroke - March 27, 2017 Category: Neurology Authors: Woo-Keun Seo, Kyungmi Oh, Sang-il Suh, Hae Young Seol Tags: Magnetic Resonance Imaging (MRI), Quality and Outcomes, Cerebrovascular Procedures, Ischemic Stroke Brief Reports Source Type: research

Baseline Blood Pressure Effect on the Benefit and Safety of Intra-Arterial Treatment in MR CLEAN (Multicenter Randomized Clinical Trial of Endovascular Treatment of Acute Ischemic Stroke in the Netherlands) Clinical Sciences
Conclusions—BP does not affect the benefit or safety of IAT in patients with acute ischemic stroke caused by proximal intracranial vessel occlusion. Our data provide no arguments to withhold or delay IAT based on BP.Clinical Trial Registration—URL: http://www.isrctn.com. Unique identifier: ISRCTN10888758.
Source: Stroke - June 26, 2017 Category: Neurology Authors: Maxim J.H.L. Mulder, Saliha Ergezen, Hester F. Lingsma, Olvert A. Berkhemer, Puck S.S. Fransen, Debbie Beumer, Lucie A. van den Berg, Geert Lycklama a Niȷeholt, Bart J. Emmer, H. Bart van der Worp, Paul J. Nederkoorn, Yvo B.W.E.M. Roos, Robert J. v Tags: High Blood Pressure, Revascularization, Stent, Cerebrovascular Disease/Stroke, Cerebrovascular Procedures Original Contributions Source Type: research

Anesthesia-Related Outcomes for Endovascular Stroke Revascularization Clinical Sciences
Conclusions—Acute ischemic stroke patients undergoing intra-arterial therapy may have worse outcomes when treated with GA as compared with conscious sedation/local anesthesia. However, major limitations of current evidence (ie, retrospective studies and selection bias) indicate a need for adequately powered, multicenter randomized controlled trials to answer this question.
Source: Stroke - September 25, 2017 Category: Neurology Authors: Waleed Brinjikji, Jeffrey Pasternak, Mohammad H. Murad, Harry J. Cloft, Tasha L. Welch, David F. Kallmes, Alejandro A. Rabinstein Tags: Revascularization, Cerebrovascular Procedures, Ischemic Stroke Original Contributions Source Type: research