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Source: Stroke
Condition: Hemorrhagic Stroke

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Total 995 results found since Jan 2013.

Admission Glucose and Effect of Intra-Arterial Treatment in Patients With Acute Ischemic Stroke Clinical Sciences
Conclusions—We found no evidence for effect modification of intra-arterial treatment by admission serum glucose in patients with acute ischemic stroke.Clinical Trial Registration—URL: www.isrctn.com. Unique identifier: ISRCTN10888758.
Source: Stroke - April 24, 2017 Category: Neurology Authors: Elizabeth Osei, Heleen M. den Hertog, Olvert A. Berkhemer, Puck S.S. Fransen, Yvo B.W.E.M. Roos, Debbie Beumer, Robert J. van Oostenbrugge, Wouter J. Schonewille, Jelis Boiten, Adrienne A.M. Zandbergen, Peter J. Koudstaal, Diederik W.J. Dippel Tags: Revascularization, Treatment, Cerebrovascular Disease/Stroke, Cerebrovascular Procedures, Ischemic Stroke Original Contributions Source Type: research

Reciprocal Interaction of 24-Hour Blood Pressure Variability and Systolic Blood Pressure on Outcome in Stroke Thrombolysis Clinical Sciences
Background and Purpose—Significance and management of blood pressure (BP) changes in acute stroke care are unclear. Here, we aimed to investigate the impact of 24-hour BP variability (BPV) on outcome in patients with acute ischemic stroke treated with intravenous thrombolysis.Methods—From the Safe Implementation of Treatment in Stroke International Stroke Thrombolysis registry, 28 976 patients with documented pre-treatment systolic BP at 2 and 24 hours were analyzed. The primary measure of BP variability was successive variability. Data were preprocessed using coarsened exact matching. We assessed early neurological ...
Source: Stroke - June 26, 2017 Category: Neurology Authors: Lars Kellert, Christian Hametner, Niaz Ahmed, Geraldine Rauch, Mary J. MacLeod, Francesco Perini, Kennedy R. Lees, Peter A. Ringleb Tags: Ischemic Stroke Original Contributions Source Type: research

Real-World Setting Comparison of Nonvitamin-K Antagonist Oral Anticoagulants Versus Vitamin-K Antagonists for Stroke Prevention in Atrial Fibrillation Clinical Sciences
Conclusions—This meta-analysis confirms the main findings of the randomized controlled trials of dabigatran, rivaroxaban, and apixaban in the real-world setting and, hence, strengthens their validity.
Source: Stroke - August 28, 2017 Category: Neurology Authors: George Ntaios, Vasileios Papavasileiou, Konstantinos Makaritsis, Konstantinos Vemmos, Patrik Michel, Gregory Y.H. Lip Tags: Arrhythmias, Secondary Prevention, Meta Analysis, Mortality/Survival, Ischemic Stroke Original Contributions Source Type: research

Palliative Care for Hospitalized Patients With Stroke Clinical Sciences
This study explores patterns of palliative care utilization and death in hospitalized patients with stroke across the United States.Methods—Using the 2010 to 2012 nationwide inpatient sample databases, we included all patients discharged with stroke identified by International Classification of Diseases-Ninth Revision codes. Strokes were subclassified as ischemic, intracerebral, and subarachnoid hemorrhage. We compared demographics, comorbidities, procedures, and outcomes between patients with and without a palliative care encounter (PCE) as defined by the International Classification of Diseases-Ninth Revision code V66....
Source: Stroke - August 28, 2017 Category: Neurology Authors: Tarvinder Singh, Steven R. Peters, David L. Tirschwell, Claire J. Creutzfeldt Tags: Race and Ethnicity, Quality and Outcomes, Cerebrovascular Disease/Stroke, Intracranial Hemorrhage, Ischemic Stroke Original Contributions Source Type: research

White Matter Hyperintensity Volume and Outcome of Mechanical Thrombectomy With Stentriever in Acute Ischemic Stroke Brief Report
Conclusions—Mechanical thrombectomy using stentrievers seems to be safe in selected patients with acute ischemic stroke with large vessel occlusion, nonwithstanding the severity of WMH burden in this population. Larger prospective studies are warranted to validate these findings.
Source: Stroke - September 25, 2017 Category: Neurology Authors: Kunakorn Atchaneeyasakul, Thabele Leslie-Mazwi, Kathleen Donahue, Anne-Katrin Giese, Natalia S. Rost Tags: Cerebrovascular Disease/Stroke, Ischemic Stroke Brief Reports Source Type: research

PROMIS GH (Patient-Reported Outcomes Measurement Information System Global Health) Scale in Stroke Clinical Sciences
The objective of this study was to evaluate the psychometric properties of PROMIS GH in patients with ischemic stroke and intracerebral hemorrhage.Methods—PROMIS GH and 6 PROMIS domain scales measuring same/similar constructs were electronically collected on 1102 patients with ischemic and hemorrhagic strokes at various stages of recovery from their stroke who were seen in a cerebrovascular clinic from October 12, 2015, through June 2, 2017. Confirmatory factor analysis was performed to evaluate the adequacy of 2-factor structure of component scores. Test–retest reliability and convergent validity of PROMIS GH items an...
Source: Stroke - December 22, 2017 Category: Neurology Authors: Irene L. Katzan, Brittany Lapin Tags: Quality and Outcomes, Intracranial Hemorrhage, Ischemic Stroke Original Contributions Source Type: research

Taurine Reduces tPA (Tissue-Type Plasminogen Activator)-Induced Hemorrhage and Microvascular Thrombosis After Embolic Stroke in Rat Basic Sciences
Conclusions—Our results suggest that taurine in combination with tPA may be a clinically feasible approach toward future attempts at combination stroke therapy.
Source: Stroke - June 25, 2018 Category: Neurology Authors: Rong Jin, Adam Y. Xiao, Shan Liu, Min Wang, Guohong Li Tags: Animal Models of Human Disease, Ischemic Stroke Original Contributions Source Type: research

Common Variants Within Oxidative Phosphorylation Genes Influence Risk of Ischemic Stroke and Intracerebral Hemorrhage Clinical Sciences
Conclusions— This pathway analysis demonstrates association between common genetic variants within OXPHOS genes and stroke. The associations for small vessel stroke and deep ICH suggest that genetic variation in OXPHOS influences small vessel pathobiology. Further studies are needed to identify culprit genetic variants and assess their functional consequences.
Source: Stroke - February 25, 2013 Category: Neurology Authors: Anderson, C. D., Biffi, A., Nalls, M. A., Devan, W. J., Schwab, K., Ayres, A. M., Valant, V., Ross, O. A., Rost, N. S., Saxena, R., Viswanathan, A., Worrall, B. B., Brott, T. G., Goldstein, J. N., Brown, D., Broderick, J. P., Norrving, B., Greenberg, S. M Tags: Acute Cerebral Hemorrhage, Acute Cerebral Infarction, Brain Circulation and Metabolism, Genetics of Stroke Clinical Sciences Source Type: research

External Validation of the SEDAN Score for Prediction of Intracerebral Hemorrhage in Stroke Thrombolysis Clinical Sciences
Conclusions— In this very large data set, the predictive and discriminatory performances of the SEDAN score were only moderate for SICH per ECASS II and low for SICH per SITS–Monitoring Study.
Source: Stroke - May 24, 2013 Category: Neurology Authors: Mazya, M. V., Bovi, P., Castillo, J., Jatuzis, D., Kobayashi, A., Wahlgren, N., Ahmed, N. Tags: Acute Cerebral Infarction, Emergency treatment of Stroke, Thrombolysis Clinical Sciences Source Type: research

Caffeine-Containing Medicines Increase the Risk of Hemorrhagic Stroke Clinical Sciences
Conclusions— These results suggest that use of CCMs is associated with increased risk of HS, both subarachnoid hemorrhage and intracerebral hemorrhage.
Source: Stroke - July 22, 2013 Category: Neurology Authors: Lee, S.-M., Choi, N.-K., Lee, B.-C., Cho, K.-H., Yoon, B.-W., Park, B.-J. Tags: Behavioral Changes and Stroke, Cerebral Aneurysm, AVM, & Subarachnoid hemorrhage, Intracerebral Hemorrhage, Risk Factors for Stroke, Epidemiology Clinical Sciences Source Type: research

Combined Approach to Lysis Utilizing Eptifibatide and Recombinant Tissue Plasminogen Activator in Acute Ischemic Stroke-Enhanced Regimen Stroke Trial Major Clinical Trial
Conclusions— The combined regimen of intravenous rt-PA and eptifibatide studied in this trial was safe and provides evidence that a phase III trial is warranted to determine efficacy of the regimen. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT00894803.
Source: Stroke - August 26, 2013 Category: Neurology Authors: Pancioli, A. M., Adeoye, O., Schmit, P. A., Khoury, J., Levine, S. R., Tomsick, T. A., Sucharew, H., Brooks, C. E., Crocco, T. J., Gutmann, L., Hemmen, T. M., Kasner, S. E., Kleindorfer, D., Knight, W. A., Martini, S., McKinney, J. S., Meurer, W. J., Meye Tags: Emergency treatment of Stroke, Antiplatelets, Thrombolysis Major Clinical Trial Source Type: research

Impact of Stroke Care Unit on Patient Outcomes in a Community Hospital Clinical Sciences
Conclusions— Establishing a SCU in a community hospital not only increases the survival of stroke patients, but also the proportion of patients discharged home to live independently. The benefits of SCU reported in larger tertiary centers extend to smaller community hospitals with more limited resources.
Source: Stroke - December 23, 2013 Category: Neurology Authors: Tamm, A., Siddiqui, M., Shuaib, A., Butcher, K., Jassal, R., Muratoglu, M., Buck, B. H. Tags: Health policy and outcome research, Acute Cerebral Hemorrhage, Acute Cerebral Infarction, Other Stroke Treatment - Medical Clinical Sciences Source Type: research

North American SOLITAIRE Stent-Retriever Acute Stroke Registry: Choice of Anesthesia and Outcomes Clinical Sciences
Conclusions— The NASA Registry has demonstrated that clinical outcomes and survival are significantly better in patients treated with LA, without increased symptomatic intracranial hemorrhage risk. Future trials should prospectively evaluate the effect of GA on outcomes.
Source: Stroke - April 28, 2014 Category: Neurology Authors: Abou-Chebl, A., Zaidat, O. O., Castonguay, A. C., Gupta, R., Sun, C.-H. J., Martin, C. O., Holloway, W. E., Mueller-Kronast, N., English, J. D., Linfante, I., Dabus, G., Malisch, T. W., Marden, F. A., Bozorgchami, H., Xavier, A., Rai, A. T., Froehler, M. Tags: Acute Cerebral Infarction, Emergency treatment of Stroke, Other Stroke Treatment - Surgical Clinical Sciences Source Type: research

Safety of Thrombolysis in Patients With Acute Ischemic Stroke and Cerebral Cavernous Malformations Brief Reports
Conclusions— Given the limitations of our study (mainly low number of patients with CCM), the risk of thrombolysis-associated hemorrhage in patients with CCM remains uncertain. Although our data do not suggest an increased hazard from thrombolysis in patients with CCM, larger studies are necessary to determine definitively the influence of CCMs on parenchymal hemorrhage and symptomatic intracerebral hemorrhage.
Source: Stroke - May 27, 2014 Category: Neurology Authors: Erdur, H., Scheitz, J. F., Tutuncu, S., Fiebach, J. B., Endres, M., Werring, D. J., Nolte, C. H. Tags: Acute Cerebral Infarction, Cerebral Aneurysm, AVM, & Subarachnoid hemorrhage, Emergency treatment of Stroke, Intracerebral Hemorrhage, Thrombolysis Brief Reports Source Type: research

Race/Ethnic Differences in the Risk of Hemorrhagic Complications Among Patients With Ischemic Stroke Receiving Thrombolytic Therapy Clinical Sciences
Conclusions— In patients with stroke receiving tPA, hemorrhagic complications were slightly higher in blacks and Asians, but not in Hispanics compared with whites. Asians also faced significantly higher risk for sICH relative to other race/ethnic groups. Future studies are needed to evaluate whether reduction in tPA dose similar to that used in many Asian countries could improve the safety of tPA therapy in Asians in the United States with acute ischemic strokes while maintaining efficacy.
Source: Stroke - July 28, 2014 Category: Neurology Authors: Mehta, R. H., Cox, M., Smith, E. E., Xian, Y., Bhatt, D. L., Fonarow, G. C., Peterson, E. D., for the Get With The Guidelines-Stroke Program Tags: Thrombolysis Clinical Sciences Source Type: research