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Condition: Sleep Disorders
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Total 3019 results found since Jan 2013.
Integrative oral medicine: Dentistry's role in improving health outcomes
CONCLUSIONS: A thorough dental examination, including a comprehensive periodontal evaluation, can provide important information that can be used to improve or maintain a patient's systemic health. Treatments provided to improve oral health have been shown to improve systemic indicators of cardiovascular health. This is the basis of integrative oral medicine, a collaboration between the medical and dental providers, which can offer patients the best opportunity for improved health outcomes.CLINICAL SIGNIFICANCE: Periodontal disease, caries, periapical infections, and sleep apnea all have negative systemic health consequence...
Source: Atherosclerosis - July 10, 2023 Category: Cardiology Authors: Doug Thompson Source Type: research
Preface: Special issue “”
The special issue “Brain Proteostasis in Health and Disease” features both original and review articles written by specialists in the field of protein homeostasis. Deregulation of adequate proteostasis may contribute to brain diseases, including several neuropsychiatric and neurodegenerative conditions. Therefore , delineating the processes underlying protein synthesis, folding, stability, function, and degradation in brain cells is key to promoting brain function and identifying effective therapeutic options for neurological disorders. This special issue covers the roles of protein homeostasis in several me chanisms t...
Source: Journal of Neurochemistry - July 7, 2023 Category: Neuroscience Authors: Mychael V. Lourenco Tags: EDITORIAL Source Type: research
Sleep-related rhythmic movement disorder in adults - A systematic review with a case report
J Sleep Res. 2023 Jul 6:e13985. doi: 10.1111/jsr.13985. Online ahead of print.ABSTRACTSleep-related rhythmic movement disorder is characterised by stereotyped and repetitive rhythmic movements involving large muscle groups during sleep with frequencies between 0.5 and 2 Hz. Most of the published studies on sleep-related rhythmic movement disorder have focussed on children. Therefore, we performed a systematic review on this topic focussing on the adult population. The review is followed by a case report. The review was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses 2020 ...
Source: Journal of Sleep Research - July 6, 2023 Category: Sleep Medicine Authors: Monika Michalek-Zrabkowska Mieszko Wieckiewicz Adam Wichniak Andrej Jenca Janka Jencova Weronika Frosztega Tomasz Wieczorek Justyna Chojdak-Lukasiewicz Monika Sluzewska-Niedzwiedz Anna Wojakowska Rafal Poreba Grzegorz Mazur Helena Martynowicz Source Type: research
Preface: Special issue “Brain Proteostasis in Health and Disease”
The special issue “Brain Proteostasis in Health and Disease” features both original and review articles written by specialists in the field of protein homeostasis. Deregulation of adequate proteostasis may contribute to brain diseases, including several neuropsychiatric and neurodegenerative conditions. Therefore , delineating the processes underlying protein synthesis, folding, stability, function, and degradation in brain cells is key to promoting brain function and identifying effective therapeutic options for neurological disorders. This special issue covers the roles of protein homeostasis in several me chanisms t...
Source: Journal of Neurochemistry - July 6, 2023 Category: Neuroscience Authors: Mychael V. Lourenco Tags: EDITORIAL Source Type: research
The broad-spectrum activity of perampanel: state of the art and future perspective of AMPA antagonism beyond epilepsy
Glutamate is the brain’s main excitatory neurotransmitter. Glutamatergic neurons primarily compose basic neuronal networks, especially in the cortex. An imbalance of excitatory and inhibitory activities may result in epilepsy or other neurological and psychiatric conditions. Among glutamate receptors, AMPA receptors are the predominant mediator of glutamate-induced excitatory neurotransmission and dictate synaptic efficiency and plasticity by their numbers and/or properties. Therefore, they appear to be a major drug target for modulating several brain functions. Perampanel (PER) is a highly selective, noncompetitive AMPA...
Source: Frontiers in Neurology - July 6, 2023 Category: Neurology Source Type: research
Improving sleep after stroke: A randomised controlled trial of digital cognitive behavioural therapy for insomnia
J Sleep Res. 2023 Jul 5:e13971. doi: 10.1111/jsr.13971. Online ahead of print.ABSTRACTStroke is frequently accompanied by long-term sleep disruption. We therefore aimed to assess the efficacy of digital cognitive behavioural therapy for insomnia to improve sleep after stroke. A parallel group randomised controlled trial was conducted remotely in participant's homes/online. Randomisation was online with minimisation of between-group differences in age and baseline Sleep Condition Indicator-8 score. In total, 86 community-dwelling stroke survivors consented, of whom 84 completed baseline assessments (39 female, mean 5.5 year...
Source: Journal of Sleep Research - July 5, 2023 Category: Sleep Medicine Authors: Melanie K Fleming Tom Smejka Ellie Macey Ramon Luengo-Fernandez Alasdair L Henry Barbara Robinson Simon D Kyle Colin A Espie Heidi Johansen-Berg Source Type: research
Cannabinoids: Emerging sleep modulator
Biomed Pharmacother. 2023 Jul 3;165:115102. doi: 10.1016/j.biopha.2023.115102. Online ahead of print.ABSTRACTSleep is an essential biological phase of our daily life cycle and is necessary for maintaining homeostasis, alertness, metabolism, cognition, and other key functions across the animal kingdom. Dysfunctional sleep leads to deleterious effects on health, mood, and cognition, including memory deficits and an increased risk of diabetes, stroke, and neurological disorders. Sleep is regulated by several brain neuronal circuits, neuromodulators, and neurotransmitters, where cannabinoids have been increasingly found to pla...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - July 5, 2023 Category: Drugs & Pharmacology Authors: Zhen Xuen Brandon Low Xin Ru Lee Tomoko Soga Bey Hing Goh Deepa Alex Yatinesh Kumari Source Type: research
Improving sleep after stroke: A randomised controlled trial of digital cognitive behavioural therapy for insomnia
J Sleep Res. 2023 Jul 5:e13971. doi: 10.1111/jsr.13971. Online ahead of print.ABSTRACTStroke is frequently accompanied by long-term sleep disruption. We therefore aimed to assess the efficacy of digital cognitive behavioural therapy for insomnia to improve sleep after stroke. A parallel group randomised controlled trial was conducted remotely in participant's homes/online. Randomisation was online with minimisation of between-group differences in age and baseline Sleep Condition Indicator-8 score. In total, 86 community-dwelling stroke survivors consented, of whom 84 completed baseline assessments (39 female, mean 5.5 year...
Source: Journal of Sleep Research - July 5, 2023 Category: Sleep Medicine Authors: Melanie K Fleming Tom Smejka Ellie Macey Ramon Luengo-Fernandez Alasdair L Henry Barbara Robinson Simon D Kyle Colin A Espie Heidi Johansen-Berg Source Type: research
Cannabinoids: Emerging sleep modulator
Biomed Pharmacother. 2023 Jul 3;165:115102. doi: 10.1016/j.biopha.2023.115102. Online ahead of print.ABSTRACTSleep is an essential biological phase of our daily life cycle and is necessary for maintaining homeostasis, alertness, metabolism, cognition, and other key functions across the animal kingdom. Dysfunctional sleep leads to deleterious effects on health, mood, and cognition, including memory deficits and an increased risk of diabetes, stroke, and neurological disorders. Sleep is regulated by several brain neuronal circuits, neuromodulators, and neurotransmitters, where cannabinoids have been increasingly found to pla...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - July 5, 2023 Category: Drugs & Pharmacology Authors: Zhen Xuen Brandon Low Xin Ru Lee Tomoko Soga Bey Hing Goh Deepa Alex Yatinesh Kumari Source Type: research
Sex Differences in 90-Day Functional Outcomes for Acute Ischemic Stroke Patients With Obstructive Sleep Apnea
Conclusions Males were found to have two times higher risk for developing poor functional outcomes at 90 days. This may be due to more severe oxygen desaturation, increased susceptibility to oxidative stress, and greater frequency of full airway obstruction in males. Greater emphasis on early diagnosis and treatment of OSA may be necessary to reduce the disproportionate incidence of poor functional outcomes, particularly among apneic male stroke survivors.PMID:37388591 | PMC:PMC10306317 | DOI:10.7759/cureus.39652
Source: Atherosclerosis - June 30, 2023 Category: Cardiology Authors: Adriana N Devenish Tariq Nisar Amber Criswell David McCane Dinh Thao Ken Chyuan Ling David Chiu Rajan Gadhia Source Type: research
Spatial assessment of the attributable burden of disease due to transportation noise in England
CONCLUSION: Transportation noise exposures contribute to a significant and unequal environmental disease burden in England. Omitting minor roads from the noise exposure modelling leads to underestimation of the disease burden.PMID:37390771 | DOI:10.1016/j.envint.2023.107966
Source: Environment International - June 30, 2023 Category: Environmental Health Authors: Calvin Jephcote Sierra N Clark Anna L Hansell Nigel Jones Yingxin Chen Claire Blackmore Katie Eminson Megan Evans Xiangpu Gong Kathryn Adams Georgia Rodgers Benjamin Fenech John Gulliver Source Type: research
