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Epilepsy Surgery in Adult Stroke Survivors with New-Onset Drug-Resistant Epilepsy
CONCLUSIONS: Patients with stroke-related drug-resistant epilepsy are infrequently considered for epilepsy surgery that could reduce morbidity and mortality.PMID:36373342 | DOI:10.1017/cjn.2022.300
Source: The Canadian Journal of Neurological Sciences - November 14, 2022 Category: Neurology Authors: Tresah C Antaya Britney N Le Lucie Richard Amna Qureshi Salimah Z Shariff Luciano A Sposato Jorge G Burneo Source Type: research

Dog Ownership Linked To 24% Lower Risk Of Dying Early, Research Shows
(CNN) — Need an excellent reason to add a dog to your life? How about living longer? “Our analysis found having a dog is actually protective against dying of any cause,” said Mount Sinai endocrinologist Dr. Caroline Kramer, lead author of a new systematic review of nearly 70 years of global research published Tuesday in “Circulation,” a journal of the American Heart Association. The review of the health benefits of man’s best friend analyzed research involving nearly 4 million people in the United States, Canada, Scandinavia, New Zealand, Australia and the United Kingdom. “Dog owne...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - October 8, 2019 Category: Consumer Health News Authors: Health – CBS Boston Tags: Featured Health News Offbeat Syndicated CBSN Boston CNN Dogs Source Type: news

Genetics of hyperhomocysteinemia and 1-carbon metabolism: implications for retinal structure and eye functions.
Abstract Homocysteine (Hcy); a sulfur-containing non-proteinogenic amino acid is generated as a metabolic intermediate. Hcy constitutes an important part of the "1-carbon metabolism" during methionine turnover. Elevated levels of Hcy known as hyperhomocysteinemia (HHcy) results from vitamin B deficiency, lack of exercise, smoking, excessive alcohol intake, high fat and methionine rich diet, and the underlying genetic defects. These factors directly affect the "1-carbon metabolism (methionine-Hcy-folate)" of a given cell. In fact, the Hcy levels are determined primarily by dietary intake, vitamin status, and the ge...
Source: Canadian Journal of Physiology and Pharmacology - July 31, 2019 Category: Drugs & Pharmacology Authors: George AK, Majumder A, Ice H, Homme RP, Eyob W, Tyagi SC, Singh M Tags: Can J Physiol Pharmacol Source Type: research

Phagocytosis in the Brain: Homeostasis and Disease
Conclusions and Perspectives In this review we have summarized the critical role phagocytosis plays in both CNS homeostasis and disease. While much progress has been made in recent years, many unanswered questions remain. How phagocytosis in the CNS is influenced by numerous factors, such as microenvironment or phagocytic target, have yet to be fully resolved. Additionally, the utilization of novel technologies, including in vivo imaging techniques (217), iPSC-derived microglia (213) and high-throughput screens (66), will likely contribute to further identification of phagocytic pathways and consequences of phagocytosis w...
Source: Frontiers in Immunology - April 15, 2019 Category: Allergy & Immunology Source Type: research

Epilepsia Partialis Continua of the Abdominal Musculature Caused by Acute Ischemic Stroke.
PMID: 30246670 [PubMed - as supplied by publisher]
Source: The Canadian Journal of Neurological Sciences - September 24, 2018 Category: Neurology Authors: Brigo F, Bratti A, Tavernelli V, Nardone R Tags: Can J Neurol Sci Source Type: research

Homocysteine and homocysteine-related compounds: an overview of the roles in the pathology of the cardiovascular and nervous systems.
HOMOCYSTEINE AND HOMOCYSTEINE-RELATED COMPOUNDS: AN OVERVIEW OF THE ROLES IN THE PATHOLOGY OF THE CARDIOVASCULAR AND NERVOUS SYSTEMS. Can J Physiol Pharmacol. 2018 Aug 21;: Authors: Djuric D, Jakovljevic V, Zivkovic VI, Srejovic IM Abstract Homocysteine, sulfhydryl group containing amino acid, is intermediate product during metabolism of the amino acids methionine and cysteine. Hyperhomocysteinema (HHcy) is used as a predictive risk factor for cardiovascular disorders, the stroke progression, screening for inborn errors of Met metabolism, and as a supplementary test for vitamin B12 deficiency. Two org...
Source: Canadian Journal of Physiology and Pharmacology - August 21, 2018 Category: Drugs & Pharmacology Authors: Djuric D, Jakovljevic V, Zivkovic VI, Srejovic IM Tags: Can J Physiol Pharmacol Source Type: research

Long-term Risk of a Seizure Disorder After Eclampsia.
CONCLUSION: Women with eclampsia should be reassured that, although the relative risk of a seizure disorder is higher than unaffected women, the absolute risk is extremely low (approximately one seizure/2,200 person-years). PMID: 29112665 [PubMed - as supplied by publisher]
Source: Obstetrics and Gynecology - November 3, 2017 Category: OBGYN Authors: Nerenberg KA, Park AL, Vigod SN, Saposnik G, Berger H, Hladunewich MA, Gandhi S, Silversides CK, Ray JG Tags: Obstet Gynecol Source Type: research

CNS Summit 2017 Abstracts of Poster Presentations
Conclusion: This novel technology discriminates and quantifies subtle differences in behavior and neurological impairments in subjects afflicted with neurological injury/disease. KINARM assessments can be incorporated into multi-center trials (e.g., monitoring stroke motor recovery: NCT02928393). Further studies will determine if KINARM Labs can demonstrate a clinical effect with fewer subjects over a shorter trial period. Disclosures/funding: Dr. Stephen Scott is the inventor of KINARM and CSO of BKIN Technologies.   Multiplexed mass spectrometry assay identifies neurodegeneration biomarkers in CSF Presenter: Chelsky...
Source: Innovations in Clinical Neuroscience - November 1, 2017 Category: Neuroscience Authors: ICNS Online Editor Tags: Assessment Tools biomarkers Cognition Current Issue Drug Development General Genetics Medical Issues Neurology Patient Assessment Psychopharmacology Scales Special Issues Supplements Trial Methodology clinical trials CNS Su Source Type: research