Filtered By:
Condition: Polycystic Ovary Syndrome
This page shows you your search results in order of date. This is page number 2.
Order by Relevance | Date
Total 65 results found since Jan 2013.
Polycystic ovary syndrome: a "risk-enhancing" factor for cardiovascular disease
Fertil Steril. 2022 May;117(5):924-935. doi: 10.1016/j.fertnstert.2022.03.009.ABSTRACTPolycystic ovary syndrome (PCOS) is the most common endocrine disorder among women of reproductive age and is hallmarked by hyperandrogenism, oligo-ovulation, and polycystic ovarian morphology. Polycystic ovary syndrome, particularly the hyperandrogenism phenotype, is associated with several cardiometabolic abnormalities, including obesity, dyslipidemia, elevated blood pressure, and prediabetes or type 2 diabetes. Many, but not all, studies have suggested that PCOS is associated with increased risk of cardiovascular disease (CVD), includi...
Source: Atherosclerosis - May 5, 2022 Category: Cardiology Authors: Carolyn Guan Salman Zahid Anum S Minhas Pamela Ouyang Arthur Vaught Valerie L Baker Erin D Michos Source Type: research
Heart health in polycystic ovary syndrome: time to act on the data
Fertil Steril. 2022 May;117(5):885-886. doi: 10.1016/j.fertnstert.2022.03.014.ABSTRACTPolycystic ovary syndrome (PCOS), first described over 80 years ago, is a chronic condition with gynecologic, metabolic, and psychologic manifestations. Both hyperandrogenism and insulin resistance are associated with the high prevalence of cardiometabolic risk factors described in this population. Although robust data in reproductive-age women demonstrate a high rate of obesity, impaired glucose tolerance, hypertension, dyslipidemia, and metabolic syndrome, studies show mixed results in the adolescent and menopausal age groups. There is ...
Source: Atherosclerosis - May 5, 2022 Category: Cardiology Authors: Anuja Dokras Source Type: research
Polycystic ovary syndrome: a “risk-enhancing” factor for cardiovascular disease
Polycystic ovary syndrome (PCOS) is the most common endocrine disorder among women of reproductive age and is hallmarked by hyperandrogenism, oligo-ovulation, and polycystic ovarian morphology. Polycystic ovary syndrome, particularly the hyperandrogenism phenotype, is associated with several cardiometabolic abnormalities, including obesity, dyslipidemia, elevated blood pressure, and prediabetes or type 2 diabetes. Many, but not all, studies have suggested that PCOS is associated with increased risk of cardiovascular disease (CVD), including coronary heart disease and stroke, independent of body mass index and traditional risk factors.
Source: Fertility and Sterility - May 1, 2022 Category: Reproduction Medicine Authors: Carolyn Guan, Salman Zahid, Anum S. Minhas, Pamela Ouyang, Arthur Vaught, Valerie L. Baker, Erin D. Michos Tags: Views and reviews Source Type: research
Mendelian randomization analyses for PCOS: evidence, opportunities, and challenges
Trends Genet. 2022 Jan 27:S0168-9525(22)00005-1. doi: 10.1016/j.tig.2022.01.005. Online ahead of print.ABSTRACTIdentifying etiological risk factors is significant for preventing and treating patients with polycystic ovary syndrome (PCOS). Through genetic variation, Mendelian randomization (MR) assesses causal associations between PCOS risk and related exposure factors. This emerging technology has provided evidence of causal associations of anti-Müllerian hormone (AMH) levels, sex hormone-binding globulin (SHBG) levels, menopause age, adiposity, insulin resistance (IR), depression, breast cancer, ovarian cancer, obsessive...
Source: Trends in Genetics : TIG - January 31, 2022 Category: Genetics & Stem Cells Authors: Congying Wang Wei Wu Haiyan Yang Zhenhong Ye Yue Zhao Jun Liu Liangshan Mu Source Type: research
Causes and Consequences of Polycystic Ovary Syndrome: Insights from Mendelian Randomization
CONCLUSIONS: The accumulation of genome-wide association studies in PCOS has enabled multiple MR analyses identifying factors that may cause PCOS or be caused by PCOS. This knowledge will be critical to future development of measures to prevent PCOS in girls at risk as well as prevent complications in those who have PCOS.PMID:34669940 | DOI:10.1210/clinem/dgab757
Source: The Journal of Clinical Endocrinology and Metabolism - October 20, 2021 Category: Endocrinology Authors: Tiantian Zhu Mark O Goodarzi Source Type: research
Biological and pharmacological activities of noscapine: Focusing on its receptors and mechanisms
AbstractNoscapine has been mentioned as one of the effective drugs with potential therapeutic applications. With few side effects and amazing capabilities, noscapine can be considered different from other opioids-like structure compounds. Since 1930, extensive studies have been conducted in the field of pharmacological treatments from against malaria to control cough and cancer treatment. Furthermore, recent studies have shown that noscapine and some analogues, like 9-bromonoscapine, amino noscapine, and 9-nitronoscapine, can be used to treat polycystic ovaries syndrome, stroke, and other diseases. Given the numerous resul...
Source: BioFactors - September 21, 2021 Category: Biochemistry Authors: Fahimeh Nourbakhsh,
Vahid Reza Askari Tags: Review Article Source Type: research
N-Acetylcysteine: A Review of Clinical Usefulness (an Old Drug with New Tricks)
CONCLUSION: The use of N-acetylcysteine should be considered in a number of conditions as our population ages and levels of glutathione drop. Supplementation may contribute to reducing morbidity and mortality in some chronic conditions as outlined in the article.PMID:34221501 | PMC:PMC8211525 | DOI:10.1155/2021/9949453
Source: Journal of Nutrition and Metabolism - July 5, 2021 Category: Nutrition Authors: Gerry K Schwalfenberg Source Type: research
