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Metabolic Syndrome and Non-Cardiac Vascular Diseases: an Update from Human Studies.
Abstract The metabolic syndrome (MetS) is characterized by a cluster of risk factors including central obesity, hypertension, dyslipidemia and insulin resistance, The MetS is associated with an increased risk for cardiovascular disease (CVD) and type 2 diabetes mellitus (T2DM). Several international organizations have defined MetS using different diagnostic criteria that produced discrepancies in the results of previous studies, thus leading to the latest Joint Interim Societies (JIS) MetS definition. Other risk factors than the diagnostic criteria that have been associated with MetS include lipid abnormalities, u...
Source: Current Pharmaceutical Design - December 5, 2013 Category: Drugs & Pharmacology Authors: Katsiki N, Athyros VG, Karagiannis A, Mikhailidis DP Tags: Curr Pharm Des Source Type: research

Cardiology for gynecologists—A minireview
Abstract: Despite cardiovascular disease (CVD) being by far the most common cause of death in women worldwide, awareness is low. Myocardial infarction occurs 10 years later in women than in men. Symptoms may be atypical: dyspnea rather than chest pain. Also more women than men have myocardial infarction with normal coronary angiography, probably due to microvascular disease or coronary spasm. The prognosis of non-obstructive disease is now recognized to be the same than for obstructive disease. The conventional risk factors for CVD are the same for both genders but have a different impact for women. One example is psychoso...
Source: Maturitas - May 13, 2013 Category: Primary Care Authors: Karin Schenck-Gustafsson, Margaret Rees Tags: Mini review Source Type: research

Diabetes and cardiovascular events in women with polycystic ovary syndrome: a 20‐year retrospective cohort study
ConclusionWe have shown a high incidence and age‐group‐specific prevalence of T2DM, MI and angina in the women with PCOS, with over a quarter having had MI or angina in those >65 years. These findings should be considered in the treatment strategies and long‐term planning for women with PCOS.
Source: Clinical Endocrinology - April 6, 2013 Category: Endocrinology Authors: Hamidreza Mani, Miles J. Levy, Melanie J. Davies, Danielle H. Morris, Laura J. Gray, John Bankart, Hannah Blackledge, Kamlesh Khunti, Trevor A. Howlett Tags: Original Article Source Type: research

Women With Polycystic Ovary Syndrome Seem To Have Higher Risk Of Heart Attack And Stroke
A syndrome common in women of reproductive age may place them at greater risk for hardening of the arteries, which predisposes them to heart attack and stroke, according to research published Feb. 15 in the American Journal of Physiology, Endocrinology and Metabolism. Glucose can stimulate an inflammatory process that allows white blood cells to enter the artery walls and attract cholesterol. Researchers studied 18- to 40-year-old women, lean and obese, with polycystic ovary syndrome and weight-matched controls...
Source: Health News from Medical News Today - February 20, 2013 Category: Consumer Health News Tags: Women's Health / Gynecology Source Type: news

Psychiatric remission with warfarin: Should psychosis be addressed as plasminogen activator imbalance?
Conclusion: Our findings suggest that normalization of plasminogen activator levels in the brain may induce long-term remission of psychotic symptoms. Randomized controlled studies may help clarify the role of anticoagulation in the treatment of psychosis.
Source: Medical Hypotheses - December 3, 2012 Category: Biomedical Science Authors: Silvia Hoirisch-Clapauch, Antonio E. Nardi Tags: Articles Source Type: research

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