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Total 8092 results found since Jan 2013.
Pharmacological interventions for asymptomatic carotid stenosis
CONCLUSIONS: Although there is no high-certainty evidence to support pharmacological intervention, this does not mean that pharmacological treatments are ineffective in preventing ischaemic cerebral events, morbidity, and mortality. High-quality RCTs are needed to better inform the best medical treatment that may reduce the burden of carotid stenosis. In the interim, clinicians will have to use other sources of information.PMID:37565307 | PMC:PMC10401652 | DOI:10.1002/14651858.CD013573.pub2
Source: Cochrane Database of Systematic Reviews - August 11, 2023 Category: General Medicine Authors: Caroline Nb Clezar Carolina Dq Flumignan Nicolle Cassola Luis Cu Nakano Virginia Fm Trevisani Ronald Lg Flumignan Source Type: research
COVID-19 ’ s Impact on Heart Health Still Confounds Doctors
(ST. LOUIS) — Firefighter and paramedic Mike Camilleri once had no trouble hauling heavy gear up ladders. Now battling long COVID, he gingerly steps onto a treadmill to learn how his heart handles a simple walk.
“This is, like, not a tough-guy test so don’t fake it,” warned Beth Hughes, a physical therapist at Washington University in St. Louis.
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Somehow, a mild case of COVID-19 set off a chain reaction that eventually left Camilleri with dangerous blood pressure spikes, a heartbeat that raced with slight exertion, and episodes of intense chest pain...
Source: TIME: Health - August 10, 2023 Category: Consumer Health News Authors: Lauran Needgaard/ Associated Press Tags: Uncategorized COVID-19 healthscienceclimate wire Source Type: news
Bioinformatic platforms for clinical stratification of natural history of atherosclerotic cardiovascular diseases
Eur Heart J Cardiovasc Pharmacother. 2023 Aug 10:pvad059. doi: 10.1093/ehjcvp/pvad059. Online ahead of print.ABSTRACTAlthough bioinformatic methods gained a lot of attention in the latest years, their use in real-world studies for primary and secondary prevention of atherosclerotic cardiovascular diseases (ASCVD) is still lacking. Bioinformatic resources have been applied to thousands of individuals from the Framingham Heart Study as well as health care-associated biobanks such as the UK Biobank, the Million Veteran Program, and the CARDIoGRAMplusC4D Consortium and randomized controlled trials (i.e. ODYSSEY, FOURIER, ASPRE...
Source: Atherosclerosis - August 10, 2023 Category: Cardiology Authors: Giuditta Benincasa Rosa Suades Teresa Padr ò Lina Badimon Claudio Napoli Source Type: research
Low-Dose Colchicine for Secondary Prevention of Coronary Artery Disease: JACC Review Topic of the Week
J Am Coll Cardiol. 2023 Aug 15;82(7):648-660. doi: 10.1016/j.jacc.2023.05.055.ABSTRACTAmong statin-treated patients, inflammation assessed by means of high-sensitivity C-reactive protein (hsCRP) is a more powerful determinant of cardiovascular death and all-cause mortality than low-density-lipoprotein cholesterol (LDL-C). Several therapies that target residual inflammatory risk significantly reduce vascular event rates. For coronary artery disease patients already taking guideline-directed medical care, including statins, low-dose colchicine (0.5 mg/d orally) has been shown to safely lower major adverse cardiovascular even...
Source: Atherosclerosis - August 9, 2023 Category: Cardiology Authors: Kyle Nelson Valentin Fuster Paul M Ridker Source Type: research
Fixed-Dose Combination Therapy for Prevention of Cardiovascular Diseases in CKD: An Individual Participant Data Meta-analysis
CONCLUSIONS: A fixed-dose combination treatment strategy is effective and safe at preventing cardiovascular disease, irrespective of eGFR but relative and absolute risk reductions are larger in individuals with low eGFR.PMID:37550842 | DOI:10.2215/CJN.0000000000000251
Source: Clinical Journal of the American Society of Nephrology : CJASN - August 8, 2023 Category: Urology & Nephrology Authors: Sadaf G Sepanlou Johannes F E Mann Philip Joseph Prem Pais Peggy Gao Maryam Sharafkhah Gholamreza Roshandel Salim Yusuf Reza Malekzadeh Source Type: research
Admission LDL-cholesterol, statin pretreatment and early outcomes in acute ischemic stroke
Elevated LDL-cholesterol (LDL-C) levels increase the risk of stroke and vascular events. Initiation and maintenance of lipid-lowering therapy after acute ischemic stroke (AIS) appears to be guided by LDL-C levels.1 The EUROASPIRE III stroke-specific module shows that secondary prevention and risk factor control in patients after ischemic stroke need to be improved since about half of patients are not achieving target lipid levels defined in European guidelines.2 However, lower levels of LDL-C are paradoxically associated with increased mortality in ST elevation myocardial infarction patients.
Source: Journal of Clinical Lipidology - August 7, 2023 Category: Lipidology Authors: Joon-Tae Kim, Ji Sung Lee, Beom Joon Kim, Jihoon Kang, Keon-Joo Lee, Jong-Moo Park, Kyusik Kang, Soo Joo Lee, Jae Guk Kim, Jae-Kwan Cha, Dae-Hyun Kim, Tai Hwan Park, Kyungbok Lee, Jun Lee, Keun-Sik Hong, Yong-Jin Cho, Hong-Kyun Park, Byung-Chul Lee, Kyung Tags: Original Research Source Type: research
Results of a 12-Month Randomized Controlled Trial Testing the Efficacy of the Diabetes Prevention Program Group Lifestyle Balance (DPP-GLB) for People Post Stroke (GLB-CVA)
CONCLUSIONS: Engagement in the GLB-CVA can result in weight loss and improved health for individuals who are overweight or obese following stroke. Future efforts should examine effectiveness in real-world settings and focus on knowledge translation efforts.PMID:37542523 | DOI:10.1093/abm/kaad045
Source: Annals of Behavioral Medicine - August 5, 2023 Category: Psychiatry & Psychology Authors: Simon Driver Evan McShan Chad Swank Stephanie Calhoun Megan Douglas Alexandria Suhalka Monica Bennett Librada Callender Christa Ochoa Sridevi Mukkamala Kaye Kramer Source Type: research
Monitoring Risk and Preventing Ischemic Stroke in the Very Old
This article examines current guidelines and evidence regarding medical management, lifestyle changes, and psychosocial interactions that can contribute to the primary and secondary prevention of ischemic stroke in the very old.AREAS COVERED: The authors conducted a literature search for ischemic stroke prevention and risk assessment in the elderly via PubMed. Furthermore, they describe current strategies for monitoring risk and preventing ischemic stroke in the elderly population.EXPERT OPINION: Ischemic stroke poses a significant health risk to the elderly, with prevention relying on managing modifiable risk factors such...
Source: Expert Review of Neurotherapeutics - August 4, 2023 Category: Neurology Authors: Mychael Delgardo Grant Rubin Thilan Tudor Anthony J Tang Geoffrey Reeves E Sander Connolly Source Type: research
