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Condition: Intermittent Claudication
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Total 94 results found since Jan 2013.

Association between home-based exercise using a pedometer and clinical prognosis after endovascular treatment in patients with peripheral artery disease
CONCLUSIONS: Good self-recording of pedometer measurements was associated with favorable prognosis in patients with PAD following EVT.PMID:36126908 | DOI:10.1016/j.jjcc.2022.09.005
Source: Journal of Cardiology - September 20, 2022 Category: Cardiology Authors: Kohei Kawamura Kentaro Ejiri Hironobu Toda Toshiaki Yamanaka Masato Taniguchi Kenji Kawamoto Koji Tokioka Yoichiro Naito Ryo Yoshioka Eiji Karashima Hideki Fujio Soichiro Fuke Yasukazu Fujiwara Atsushi Takaishi Kosuke Seiyama Toru Miyoshi Kazufumi Nakamur Source Type: research

Update on Cilostazol: A Critical Review of its Antithrombotic and Cardiovascular Actions and its Clinical Applications
This article is protected by copyright. All rights reserved.PMID:34671983 | DOI:10.1002/jcph.1988
Source: The Journal of Clinical Pharmacology - October 21, 2021 Category: Drugs & Pharmacology Authors: Antonis A Manolis Theodora A Manolis Helen Melita Dimitri P Mikhailidis Antonis S Manolis Source Type: research

Letter to the Editor on “Traditional Cardiovascular Risk Factors Strongly Underestimate the 5-Year Occurrence of Cardiovascular Morbidity and Mortality in Spinal Cord Injured Individuals”
Barton et al's1 article studies cardiovascular risk in a cohort of individuals with a spinal cord injury (SCI). As the authors noted, the Framingham Risk Score (FRS) was derived to identify risk factors for cardiovascular disease. It is important to note, however, that the outcome measure for this risk score is defined as a “composite of coronary heart disease (coronary death, myocardial infarction, coronary insufficiency, and angina), cerebrovascular events (including ischemic stroke, hemorrhagic stoke, and transient ischemic attack), peripheral artery disease (intermittent claudication), and heart failure.”2 This com...
Source: Archives of Physical Medicine and Rehabilitation - July 17, 2021 Category: Rehabilitation Authors: Brian Higdon Tags: Letter to the Editor Source Type: research

Borderzone Infarction and Small Vessel Disease in a Sample of Egyptian Stroke Patients: Differences and Similarities
Conclusion: Limb shaking, retinal claudication or syncope, with MRI showing rosary pattern of white matter hyperintensity, few microbleeds and markedly impaired perfusion favor the diagnosis of borderzone infarctions. On the other hand, presence of lacunae, FLAIR showing symmetrical WMH and microbleeds with minimal or no perfusion deficit suggests the diagnosis of small vessel disease.
Source: Neurology India - June 24, 2021 Category: Neurology Authors: Nevine M El Nahas Hany M Aref Taha K Alloush Nagia A Fahmy Khaled A Ahmed Ahmed A El Basiouny Mohamed A Tork Ahmed M Elbokl Hossam M Shokri Source Type: research

New Directions in Therapeutic Angiogenesis and Arteriogenesis in Peripheral Arterial Disease
Circ Res. 2021 Jun 11;128(12):1944-1957. doi: 10.1161/CIRCRESAHA.121.318266. Epub 2021 Jun 10.ABSTRACTThe prevalence of peripheral arterial disease (PAD) in the United States exceeds 10 million people, and PAD is a significant cause of morbidity and mortality across the globe. PAD is typically caused by atherosclerotic obstructions in the large arteries to the leg(s). The most common clinical consequences of PAD include pain on walking (claudication), impaired functional capacity, pain at rest, and loss of tissue integrity in the distal limbs that may lead to lower extremity amputation. Patients with PAD also have higher t...
Source: Circulation Research - June 10, 2021 Category: Cardiology Authors: Brian H Annex John P Cooke Source Type: research

Cilostazol: a Review of Basic Mechanisms and Clinical Uses
AbstractPrimarily used in the treatment of intermittent claudication, cilostazol is a 2-oxyquinolone derivative that works through the inhibition of phosphodiesterase III and related increases in cyclic adenosine monophosphate (cAMP) levels. However, cilostazol has been implicated in a number of other basic pathways including the inhibition of adenosine reuptake, the inhibition of multidrug resistance protein 4, among others. It has been observed to exhibit antiplatelet, antiproliferative, vasodilatory, and ischemic-reperfusion protective properties. As such, cilostazol has been investigated for clinical use in a variety o...
Source: Cardiovascular Drugs and Therapy - April 16, 2021 Category: Cardiology Source Type: research

Higher long-term cardiovascular morbidity after open surgery for intermittent claudication caused by infrainguinal atherosclerotic disease in patients with diabetes - a nationwide observational cohort study.
Conclusions: DM patients showed higher rates of MACE and AMI in propensity score adjusted analysis five years after planned infrainguinal open surgery for IC. Higher HbA1c was associated with MACE, stroke, and total mortality in patients with DM, whereas longer duration of DM was associated with major amputation. PMID: 33334201 [PubMed - as supplied by publisher]
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - December 18, 2020 Category: Surgery Authors: Dakhel A, Zarrouk M, Ekelund J, Acosta S, Miftaraj M, Eliasson B, Svensson AM, Gottsäter A Tags: Vasa Source Type: research

Biologics May Prevent Cardiovascular Events in Rheumatoid Arthritis by Inhibiting Coronary Plaque Formation and Stabilizing High ‐Risk Lesions
ConclusionOur findings indicate that in RA, biologic DMARD use is associated with reduced CVD risk, protective calcification of noncalcified lesions, and lower likelihood of new plaque formation in patients with early atherosclerosis.
Source: Arthritis and Rheumatology - August 6, 2020 Category: Rheumatology Authors: George A. Karpouzas, Sarah R. Ormseth, Elizabeth Hernandez, Matthew J. Budoff Tags: Original Article Source Type: research

Biologics may prevent cardiovascular events in rheumatoid arthritis by inhibiting coronary plaque formation and stabilizing high ‐risk lesions
ConclusionIn rheumatoid arthritis, bDMARD use associated with reduced CVD risk, protective calcification of non ‐calcified lesions and lower likelihood of new plaque formation in patients with early atherosclerosis.
Source: Arthritis and Rheumatology - April 20, 2020 Category: Rheumatology Authors: George A Karpouzas, Sarah R Ormseth, Elizabeth Hernandez, Matthew J Budoff Tags: FULL LENGTH Source Type: research

Arterial hypertension and diabetes association in the elderly
ConclusionVascular metabolic complications are serious in hypertensive elderly diabetic subjects; thus, multidisciplinary care and regular monitoring is required to detect these complications early and improve life expectancy.
Source: Archives of Cardiovascular Diseases Supplements - July 24, 2019 Category: Cardiology Source Type: research