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Condition: Heatstroke
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Total 1318 results found since Jan 2013.
Ablation of Calsequestrin-1, Ca2+ unbalance, and susceptibility to heat stroke
Introduction: Ca2+ levels in adult skeletal muscle fibers are mainly controlled by excitation-contraction (EC) coupling, a mechanism that translates action potentials in release of Ca2+ from the sarcoplasmic reticulum (SR) release channels, i.e. the ryanodine receptors type-1 (RyR1). Calsequestrin (Casq) is a protein that binds large amounts of Ca2+ in the lumen of the SR terminal cisternae, near sites of Ca2+ release. There is general agreement that Casq is not only important for the SR ability to store Ca2+, but also for modulating the opening probability of the RyR Ca2+ release channels.The initial studies: About 20 ye...
Source: Frontiers in Physiology - October 12, 2022 Category: Physiology Source Type: research
IJERPH, Vol. 19, Pages 12448: A Potential Driver of Disseminated Intravascular Coagulation in Heat Stroke Mice: Neutrophil Extracellular Traps
Conclusions: Degradation of NETs reduced the risk of developing DIC, and thus the survival rate of mice was improved. These results indicate that NETs may hold potential alternative therapeutic strategies for the treatment of DIC in HS patients.
Source: International Journal of Environmental Research and Public Health - September 29, 2022 Category: Environmental Health Authors: Yuling Zhang Xiling Deng Jing Zhang Liang Zhang Zubair Akram Bo Zhang Shiguo Sun Tags: Article Source Type: research
IOC consensus statement on recommendations and regulations for sport events in the heat
Br J Sports Med. 2022 Sep 23:bjsports-2022-105942. doi: 10.1136/bjsports-2022-105942. Online ahead of print.ABSTRACTThis document presents the recommendations developed by the IOC Medical and Scientific Commission and several international federations (IF) on the protection of athletes competing in the heat. It is based on a working group, meetings, field experience and a Delphi process. The first section presents recommendations for event organisers to monitor environmental conditions before and during an event; to provide sufficient ice, shading and cooling; and to work with the IF to remove regulatory and logistical lim...
Source: British Journal of Sports Medicine - September 23, 2022 Category: Sports Medicine Authors: Sebastien Racinais Yuri Hosokawa Takao Akama Stephane Bermon Xavier Bigard Douglas J Casa Andrew Grundstein Ollie Jay Andrew Massey Sergio Migliorini Margo Mountjoy Nebosa Nikolic Yannis P Pitsiladis Wolfgang Schobersberger Juergen Michael Steinacker Fumi Source Type: research
Exertional heat stroke in sport and the military: epidemiology and mitigation - P ériard JD, DeGroot D, Jay O.
NEW FINDINGS: What is the topic of this review? Exertional heat stroke epidemiology in sport and military settings is reviewed, along with common risk factors and strategies and policies designed to mitigate its occurrence. What advances does it highlight?...
Source: SafetyLit - September 3, 2022 Category: International Medicine & Public Health Tags: Environmental Issues, Climate, Geophysics Source Type: news
Knowledge gaps persist regarding exertional heat stroke treatment
J Athl Train. 2022 Sep 1. doi: 10.4085/1062-6050-366-19. Online ahead of print.ABSTRACTIndividualized patient care is ideal to treat and rehabilitate athletic illnesses and injuries. Exertional heat stroke (EHS) treatment best practice recommendations state all patients should undergo identical cold water immersion (CWI) treatment for ideal outcomes. It is unknown, however, if CWI can be optimized with individualized treatment plans, encouraging personalized medicine. To accomplish this task, clinicians and researchers need to better understand factors impacting CWI effectiveness. This short report will provide an update t...
Source: J Athl Train - September 1, 2022 Category: Sports Medicine Authors: Riana R Pryor J Luke Pryor Brendon P McDermott Source Type: research
