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Condition: Head Injury

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Total 157 results found since Jan 2013.

PET scans may improve brain injury diagnosis
ConclusionThis is a valuable diagnostic study that tested how accurate PET and fMRI imaging are at distinguishing between different levels of conscious state and helping to predict recovery. Diagnostic assessments are traditionally made using bedside clinical tests – but as the researchers say, judging the level of awareness in people with severe brain damage can be difficult.In particular, the researchers wanted to see whether the scans could accurately distinguish between people with “unresponsive wakefulness syndrome” and “minimally conscious state”, as distinguishing between these two states can have impor...
Source: NHS News Feed - April 16, 2014 Category: Consumer Health News Tags: Medical practice Neurology Source Type: news

Antiepileptic Drug Prescribing for OEF/OIFVeterans with New-Onset Epilepsy: 2008-2010 (S59.004)
CONCLUSIONS: Our examination of prescribing patterns found that slightly over half of individuals with new epilepsy were treated using newer AEDs and 94% received monotherapy. Despite lack of FDA approval or recommendation by the AES, AAN or the ILAE for the use of levetiracetam monotherapy in the treatment of new onset epilepsy, levetiracetam monotherapy was the most common single medication prescribed. Moreover, nearly 40% of women in childbearing age received valproate or topiramate, which have been identified as teratogenic. Further research is needed to evaluate the quality of prescribing for women.Study Supported by:...
Source: Neurology - April 9, 2014 Category: Neurology Authors: Pugh, M. J., Van Cott, A., Baca, C., Amuan, M. Tags: Epilepsy and Clinical Neurophysiology (EEG): Reproduction, Health Care Delivery, and Co-morbidities Source Type: research

Antiepileptic Drug Prescribing for OEF/OIFVeterans with New-Onset Epilepsy: 2008-2010 (I8-1.009)
CONCLUSIONS: Our examination of prescribing patterns found that slightly over half of individuals with new epilepsy were treated using newer AEDs and 94% received monotherapy. Despite lack of FDA approval or recommendation by the AES, AAN or the ILAE for the use of levetiracetam monotherapy in the treatment of new onset epilepsy, levetiracetam monotherapy was the most common single medication prescribed. Moreover, nearly 40% of women in childbearing age received valproate or topiramate, which have been identified as teratogenic. Further research is needed to evaluate the quality of prescribing for women.Study Supported by:...
Source: Neurology - April 9, 2014 Category: Neurology Authors: Pugh, M. J., Van Cott, A., Baca, C., Amuan, M. Tags: Clinical Decision Making After the Dust Settles on Clinical Trials Poster Presentations Source Type: research

Functional Outcome After Perinatal Cerebral Sinovenous Thrombosis: A Prospective Cohort Study (S42.006)
CONCLUSIONS: We found a high rate of neurological morbidity and seizure burden after perinatal CSVT which significantly impacted achievement of age-appropriate developmental milestones and function. Measures and predictors of functional outcome following perinatal CSVT need further exploration.Disclosure: Dr. Billinghurst has nothing to disclose. Dr. Uohara has nothing to disclose. Dr. Licht has nothing to disclose. Dr. Ichord has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Billinghurst, L., Uohara, M., Licht, D., Ichord, R. Tags: Child Neurology I Source Type: research

Selected Health and Life Style Factors and Time to Phenoconversion in Huntington's Disease (S47.003)
CONCLUSIONS: An association between total lifetime caffeinated soda consumption and earlier HD onset was observed, but this was not seen with other caffeinated beverages and may be spurious. Other life style risk factors associated with PD or AD did not modify time to phenoconversion in HD.SUPPORT: NIH (# 2 R01 HG002449-06), National Human Genome Research Institute, National Institute of Neurological Disorders and StrokeDisclosure: Dr. Tanner has received personal compensation for activities with AbbVie and Adamas Pharmaceuticals as a scientific advisor. Dr. Marder has received personal compensation in an editorial capacit...
Source: Neurology - April 9, 2014 Category: Neurology Authors: Tanner, C., Marder, K., Eberly, S., Biglan, K., Oakes, D., Shoulson, I. Tags: Movement Disorders: Huntington ' s Disease, Ataxia, and Wilson Source Type: research

Incretin mimetics as pharmacologic tools to elucidate and as a new drug strategy to treat traumatic brain injury.
Authors: Greig NH, Tweedie D, Rachmany L, Li Y, Rubovitch V, Schreiber S, Chiang YH, Hoffer BJ, Miller J, Lahiri DK, Sambamurti K, Becker RE, Pick CG Abstract Traumatic brain injury (TBI), either as an isolated injury or in conjunction with other injuries, is an increasingly common event. An estimated 1.7 million injuries occur within the USA each year and 10 million people are affected annually worldwide. Indeed, nearly one third (30.5%) of all injury-related deaths in the USA are associated with TBI, which will soon outpace many common diseases as the major cause of death and disability. Associated with a high mo...
Source: The Journal of Alzheimers Association - February 18, 2014 Category: Psychiatry Tags: Alzheimers Dement Source Type: research

Head Injury Triples Stroke Risk in Youth
SAN DIEGO (MedPage Today) -- Traumatic head and neck injury tripled stroke risk for young adults compared with other types of trauma injuries, a large cohort study showed.
Source: MedPage Today Cardiovascular - February 14, 2014 Category: Cardiology Source Type: news

How to measure fatigue in neurological conditions? A systematic review of psychometric properties and clinical utility of measures used so far.
Conclusion:Although many measures of fatigue in neurological conditions have published, none met all of the criteria for psychometric robustness and clinical utility but the Neurological Fatigue Indices are the best and can be used with caution. PMID: 24519920 [PubMed - as supplied by publisher]
Source: Clinical Rehabilitation - February 11, 2014 Category: Rehabilitation Authors: Tyson SF, Brown P Tags: Clin Rehabil Source Type: research

Inosine improves functional recovery after experimental traumatic brain injury.
Abstract Despite years of research, no effective therapy is yet available for the treatment of traumatic brain injury (TBI). The most prevalent and debilitating features in survivors of TBI are cognitive deficits and motor dysfunction. A potential therapeutic method for improving the function of patients following TBI would be to restore, at least in part, plasticity to the CNS in a controlled way that would allow for the formation of compensatory circuits. Inosine, a naturally occurring purine nucleoside, has been shown to promote axon collateral growth in the corticospinal tract (CST) following stroke and focal ...
Source: Brain Research - February 3, 2014 Category: Neurology Authors: Dachir S, Shabashov D, Trembovler V, Alexandrovich AG, Benowitz LI, Shohami E Tags: Brain Res Source Type: research

The causes of hypopituitarism in the absence of abnormal pituitary imaging
Conclusion: These results show that hypopituitarism in the absence of pituitary pathology or an identifiable cause is rare. In patients with multiple anterior pituitary hormone deficiencies haemochromatosis and sarcoidosis should be considered.
Source: QJM - December 20, 2013 Category: Internal Medicine Authors: Wilson, V., Mallipedhi, A., Stephens, J. W., Redfern, R. M., Price, D. E. Tags: Original papers Source Type: research

Clinical application of perfusion computed tomography in neurosurgery.
Conclusions Perfusion CT provides quantitative and qualitative data that can add diagnostic and prognostic value in a number of neurosurgical disorders, and also help with clinical decision making. With emerging new technical developments in PCT, such as characterization of blood-brain barrier permeability and whole-brain PCT, this technique is expected to provide more and more insight into the pathophysiology of many neurosurgical conditions. PMID: 24266541 [PubMed - as supplied by publisher]
Source: Journal of Neurosurgery - November 22, 2013 Category: Neurosurgery Authors: Huang AP, Tsai JC, Kuo LT, Lee CW, Lai HS, Tsai LK, Huang SJ, Chen CM, Chen YS, Chuang HY, Wintermark M Tags: J Neurosurg Source Type: research

Confusion: Causes and Symptoms
Confusion is a condition that occurs when a person has difficulty understanding a situation, or experiences unclear or disordered thoughts. It may be accompanied by disorientation, memory loss, or the inability to think quickly. Confusion may increase slowly over a period of time, or it may occur quickly, depending on the cause. It might be associated with some chronic medical conditions, serious infections, brain or spinal cord tumor, a head injury, stroke, delirium, or dementia. Confusion may also be caused by drug or alcohol intoxication, chemical or electrolyte imbalances, sleep disorders, medications, or vitamin defic...
Source: Disabled World - October 15, 2013 Category: Disability Tags: Neurological Disorders Source Type: news

Just a graze?
In conclusion, when approaching a patient with head injury and one or more cranial nerve palsies, it is important to consider cephalic tetanus. Figure 1 Axial CT head shows a large subcutaneous haematoma overlying the right frontal convexity with locules of gas and a 3mm metallic density at its inferior aspect, possibly representing a foreign body.
Source: Journal of Neurology, Neurosurgery and Psychiatry - October 9, 2013 Category: Neurosurgery Authors: Doshi, A., Dahdalleh, D., Warrell, C., Kullmann, D. Tags: Immunology (including allergy), Cranial nerves, Drugs: CNS (not psychiatric), Neurological injury, Stroke, Trauma CNS / PNS, Hypertension, Trauma, Injury Association of British Neurologists (ABN) joint meeting with the Royal College of Physicians (RCP), Source Type: research

Cognitive impairment after appropriate implantable cardioverter-defibrillator therapy for ventricular fibrillation.
CONCLUSIONS: The short periods of out-of-hospital ventricular fibrillation converted by implantable cardioverter-defibrillator are associated with cognitive impairment in the recipients of primary prevention ICD. PMID: 23990235 [PubMed - as supplied by publisher]
Source: Polish Heart Journal - August 30, 2013 Category: Cardiology Authors: Hałas K, Krzyżanowski K, Krzyżanowska E, Smurzyński P, Ryczek R, Michałkiewicz D, Orski Z, Makowski K, Wierzbowski R, Gielerak G Tags: Kardiol Pol Source Type: research