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Anxiety in Patients With Acute Ischemic Stroke: Risk Factors and Effects on Functional Status
Conclusion: Depressive symptoms are the major correlates of PSA while more severe PSA is associated with poorer ADL and health-related QOL. Acute lesions involving CHWM may correlate with PSA in ischemic stroke patients with mild-to-moderate neurologic deficits, supporting a lesion-location hypothesis in PSA.IntroductionAnxiety is prevalent after stroke and occurs in about one-quarter of stroke survivors (1, 2). Poststroke anxiety (PSA) may have a negative impact on quality of life (QOL) of stroke survivors, affecting their rehabilitation (3). Furthermore, one prospective study found that severe anxiety symptoms were assoc...
Source: Frontiers in Psychiatry - April 16, 2019 Category: Psychiatry Source Type: research

Differences in Ischaemic and Haemorrhagic Strokes in Sri Lanka: 7-year data from the Ragama Stroke Registry (P1.092)
CONCLUSIONS:Clinical and risk factor profiles were different between ICH and IS patients. Stroke severity and functional disability were higher among ICH patients. Study Supported by:Ragama Stroke Registry has been partly supported by research grants from the University of Kelaniya and Research Institute, International Medical Centre of Japan.Disclosure: Dr. Ranawaka has nothing to disclose. Dr. Peiris has nothing to disclose. Dr. Thirumavalavan has nothing to disclose. Dr. Premawansa has nothing to disclose. Dr. Kasthuriratne has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Ranawaka, U., Peiris, A., Thirumavalavan, K., Premawansa, G., Kasthuriratne, A. Tags: Neuroepidemiology: Cerebrovascular Disease, Critical Care, Epilepsy, Child Neurology, and Sleep Source Type: research

Asymptomatic Carotid Stenosis Is Associated With Circadian and Other Variability in Embolus Detection
Conclusions: Embolism associated with asymptomatic carotid stenosis shows circadian variation with highest rates 4–6 h before midday. This corresponds with peak circadian incidence of stroke and other vascular complications. These and ASED Study results show that monitoring frequency, duration, and time of day are important in ES detection. Introduction Transcranial Doppler (TCD) detected microembolism in the ipsilateral middle cerebral artery (MCA) may help stratify the risk of stroke and other arterial disease complications in persons with advanced (≥60%) asymptomatic carotid stenosis. If so, this t...
Source: Frontiers in Neurology - April 15, 2019 Category: Neurology Source Type: research

Revised Constraint-Induced Aphasia Therapy (CIAT II): Neuroscience Foundations Traced from Basic Laboratory Research to Increased Spontaneous Real-World Speech and Cerebral Cortical Structure (P4.217)
Conclusions:CIAT II has promise for promoting enduring increased spontaneous real-world speech as well as brain structure for chronic aphasia, convergent with earlier forms of CI therapies for movement. Further trials are warranted.Study Supported by: NIH grant HD0 53750.Disclosure: Dr. Mark has nothing to disclose. Dr. Taub has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Mark, V., Taub, E. Tags: Neuro-rehabilitation: Mechanism of Recovery Source Type: research

Neuroimaging and Neurolaw: Drawing the Future of Aging
Vincenzo Tigano1, Giuseppe Lucio Cascini2, Cristina Sanchez-Castañeda3, Patrice Péran4 and Umberto Sabatini5* 1Department of Juridical, Historical, Economic and Social Sciences, University of Magna Graecia, Catanzaro, Italy 2Department of Experimental and Clinical Medicine, University of Magna Graecia, Catanzaro, Italy 3Department of Clinical Psychology and Psychobiology, University of Barcelona, Barcelona, Spain 4ToNIC, Toulouse NeuroImaging Center, Université de Toulouse, Inserm, UPS, Toulouse, France 5Department of Medical and Surgical Sciences, University of Magna Graecia, Catanzaro, ...
Source: Frontiers in Endocrinology - April 7, 2019 Category: Endocrinology Source Type: research

Nonverbal Oral Apraxia in Primary Progressive Aphasia and Apraxia of Speech (P2.166)
CONCLUSIONS:We have shown that AOS, NVOA and IMA are at least partially distinct among patients with PPA and PPAOS. NVOA might be more common in patients with AOS due to the proximity of the region we identified by VBM to the premotor area, which has been implicated in AOS. The association of IMA and NVOA among patients without AOS could represent disruption of a module shared by nonverbal oral movements and limb movements.Study Supported by: NIH grant R01-DC010367Disclosure: Dr. Botha has nothing to disclose. Dr. Duffy has nothing to disclose. Dr. Strand has nothing to disclose. Dr. Whitwell has nothing to disclose. Dr. J...
Source: Neurology - April 9, 2014 Category: Neurology Authors: Botha, H., Duffy, J., Strand, E., Whitwell, J., Josephs, K. Tags: Aging, Dementia, and Cognitive and Behavioral Neurology: General Cognition Source Type: research

Tau Imaging Among Breakthroughs Advancing the Fight against Alzheimer ' s
Worldwide,  nearly44 million  people now have Alzheimer ' s disease (AD) or related dementia, making these conditions the  top cause of disabilities in later life. The biopharma industry has invested billions of dollars into research to treat and prevent AD1, yet this work has faced many obstacles, including difficulty identifying biomarkers, tracking the disease ’s progress in the brain, and recruiting patients to trials while they are still asymptomatic. But in recent years, we’ve begun to see breakthroughs that is driving our research in new directions. Many of these accomplishments were highlighted at the Alzh...
Source: EyeForPharma - September 21, 2016 Category: Pharmaceuticals Authors: Olga Uspenskaya-Cadoz Source Type: news

Harmonizing Together: Speech and Music Therapy and Support for Patients and Partners with PPA (P5.157)
Conclusions:The reports of improvement in caregiver health, social participation of patients, and functional communication are in line with the group’s focus and goals. In contrast, more comprehensive knowledge of the disease process may have led patients and caregivers to experience greater feelings of guilt and fear. Our qualitative observations and reports from participants indicated that the most beneficial parts of the group were raising patients’ confidence in communication and allowing both patients and families suffering from PPA to connect with one another.Study Supported by:Funding NIH grant NS077059;...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Quimby, M., Shaprio-Gordon, J., Brandt, K., Hyatt, C., Grimm, M., Richardson, L., Howland, K., Dickerson, B. Tags: Clinical Neuro-rehabilitation Source Type: research

Disentangling the Psycholinguistic Loci of Anomia with Cognitive Psychometric Models
This article reviews advanced statistical techniques for measuring impairments in object naming, particularly in the context of stroke-induced aphasia. Traditional testing strategies can be challenged by the multifaceted nature of impairments that arise due to the complex relationships between localized brain damage and disruption to the cognitive processes required for successful object naming. Cognitive psychometric models can combine response-type analysis with item-response theory to yield accurate estimates of multiple abilities using data collected from a single task. The models also provide insights about how the te...
Source: Seminars in Speech and Language - July 14, 2021 Category: Speech-Language Pathology Authors: Walker, Grant M. Tags: Review Article Source Type: research

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