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Total 37 results found since Jan 2013.
Can This Breakfast Food Reverse Alzheimer ’ s?
I’m sure you’ve noticed how expensive eggs have gotten lately. The price has soared more than any other food in the supermarket…up 60% from one year ago.1
One reason for skyrocketing prices is the ongoing avian flu epidemic. But another reason is that demand for “nature’s perfect food” has increased substantially.
And that is good news because eggs are essential for your health – including the fight against Alzheimer’s.
And that means they’re worth every penny for the way they protect your brain.
Two breakthrough studies back up what I’ve been telling my patients for over three decades…
That ...
Source: Al Sears, MD Natural Remedies - August 25, 2023 Category: Complementary Medicine Authors: Jacob Tags: Anti-Aging Brain Health Nutrition Source Type: news
This Overlooked Nutrient May Be The Key To Brain Power
Aging is inevitable. But have you noticed that some very elderly people still don’t miss a thing?
Some of my patients fall into this category. I’ve worked with many centenarians who remain quick-witted, with keen memories and focus.
You can be one of these people, too — an all-star senior…
Inside all of you, your cells are constantly busy dividing up to two trillion times per day. The new cells replace old, damaged, or dead cells and help you live, grow and thrive.
Human cell lines have built-in mortality. As your cells divide, there’s a limit at which their limit is reached.
There’s an internal mechanism o...
Source: Al Sears, MD Natural Remedies - August 25, 2023 Category: Complementary Medicine Authors: Jacob Tags: Brain Health Source Type: news
Too Little Sleep Destroys DNA?
I talk to my patients about the danger of not sleeping all the time. Unfortunately, it’s a common problem that affects 75 million Americans.
People who don’t sleep, or sleep poorly, have up to 400% more accidents that those who get a good night’s rest. Not getting enough sleep also increases your risk of developing chronic diseases.
Studies, including a large meta-analysis of 470,000 adults, found that those who slept less than six hours developed a:1,2,3,4,5
48% increase in the incidence of coronary heart disease
30% increased risk of dementia
15% increase in the incidence of stroke
50% cancer risk
17% higher risk ...
Source: Al Sears, MD Natural Remedies - August 25, 2023 Category: Complementary Medicine Authors: Jacob Tags: Anti-Aging Health Source Type: news
EXERTION: a pilot trial on the effect of aerobic, smartwatch-controlled exercise on stroke recovery: effects on motor function, structural repair, cognition, mental well-being, and the immune system
This study investigates the effect of smartwatch-controlled aerobic exercise on functional recovery, cognition, emotional well-being, the immune system, and neuronal network reorganization in stroke patients. Trial registration ClinicalTrials.gov NCT Number: NCT05690165. First posted19 January 2023. Retrospectively registered, https://clinicaltrials.gov/ct2/show/NCT05690165.PMID:37170385 | DOI:10.1186/s42466-023-00244-w
Source: Cell Research - May 11, 2023 Category: Cytology Authors: Frederike A Straeten Stephanie van Zyl Bastian Maus Jochen Bauer Heiner Raum Catharina C Gross Sabine Bruchmann Nils C Landmeyer Cornelius Faber Jens Minnerup Antje Schmidt-Pogoda Source Type: research
Microglial Activation Modulated by P2X4R in Ischemia and Repercussions in Alzheimer ’s Disease
There are over 80 million people currently living who have had a stroke. The ischemic injury in the brain starts a cascade of events that lead to neuronal death, inducing neurodegeneration which could lead to Alzheimer’s disease (AD). Cerebrovascular diseases have been suggested to contribute to AD neuropathological changes, including brain atrophy and accumulation of abnormal proteins such as amyloid beta (Aβ). In patients older than 60 years, the incidence of dementia a year after stroke was significantly increased. Nevertheless, the molecular links between stroke and dementia are not clearly understood but could be r...
Source: Frontiers in Physiology - February 23, 2022 Category: Physiology Source Type: research
Q & A: Dr. Thomas Rando on preventing age-related diseases and turning discoveries into cures
For Dr. Thomas Rando, the path to becoming a physician-scientist began with something that hedidn ’t learn in high school biology.After one class that touched on the connections between neurons and muscle fibers, Rando took it upon to himself to find all the information he could about how cells communicate through electrical signals.Soon, he began pursuing that interest at Harvard University, where he completed his undergraduate work, a doctorate in cell and developmental biology and his medical degree.Rando joined the neurology faculty at the Stanford University School of Medicine in 1995.There, he founded a clinic to t...
Source: UCLA Newsroom: Health Sciences - December 10, 2021 Category: Universities & Medical Training Source Type: news
4 Ways Exercise Helps Fight Aging
Everyone knows that exercise is good for you. But it’s not just beneficial for the young, healthy and already fit. It’s also one of the best defenses against the toughest aspects of aging.
Exercise not only improves heart and lung health, but research shows that even modest physical activity is good for the brain, bones, muscles and mood. Numerous studies have found that lifelong exercise may keep people healthier for longer; delay the onset of 40 chronic conditions or diseases; stave off cognitive decline; reduce the risk of falls; alleviate depression, stress and anxiety; and may even help people live longer....
Source: TIME: Health - June 1, 2021 Category: Consumer Health News Authors: Liz Seegert Tags: Uncategorized Source Type: news
Stem cell therapy promotes recovery from stroke and dementia in mice
A one-time injection of an experimental stem cell therapy can repair brain damage and improve memory function in mice with conditions that replicate human strokes and dementia,a new UCLA study finds.Dementia can arise from multiple conditions, and it is characterized by an array of symptoms including problems with memory, attention, communication and physical coordination. The two most common causes of dementia are Alzheimer ’s disease and white matter strokes — small strokes that accumulate in the connecting areas of the brain.“It’s a vicious cycle: The two leading causes of dementia are almost always seen togeth...
Source: UCLA Newsroom: Health Sciences - April 22, 2021 Category: Universities & Medical Training Source Type: news
Research Articles Patient-derived glial enriched progenitors repair functional deficits due to white matter stroke and vascular dementia in rodents
Subcortical white matter stroke (WMS) accounts for up to 30% of all stroke events. WMS damages primarily astrocytes, axons, oligodendrocytes, and myelin. We hypothesized that a therapeutic intervention targeting astrocytes would be ideally suited for brain repair after WMS. We characterize the cellular properties and in vivo tissue repair activity of glial enriched progenitor (GEP) cells differentiated from human-induced pluripotent stem cells, termed hiPSC-derived GEPs (hiPSC-GEPs). hiPSC-GEPs are derived from hiPSC–neural progenitor cells via an experimental manipulation of hypoxia inducible factor activity by brie...
Source: Science Translational Medicine - April 21, 2021 Category: Biomedical Science Authors: Llorente, I. L., Xie, Y., Mazzitelli, J. A., Hatanaka, E. A., Cinkornpumin, J., Miller, D. R., Lin, Y., Lowry, W. E., Carmichael, S. T. Tags: Research Articles Source Type: research
Thomas Carmichael elected to the Association of American Physicians
Dr. S. Thomas Carmichael has been elected to the Association of American Physicians, an honor society recognizing exemplary physician-scientists who contribute to clinical medicine through the pursuit of basic science. The newly elected members for 2021 were recognized at the association ’s annual meeting, which was held virtually April 8–10.Carmichael, UCLA ’s Frances Stark Professor of Neurology, is the chair of theneurology department in the David Geffen School of Medicine at UCLA and co-director of theEli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA.In his research, Carmichael s...
Source: UCLA Newsroom: Health Sciences - April 9, 2021 Category: Universities & Medical Training Source Type: news
Thomas Carmichael elected to Association of American Physicians
Dr. S. Thomas Carmichael has been elected to the Association of American Physicians, an honor society recognizing exemplary physician-scientists who contribute to clinical medicine through the pursuit of basic science. The newly elected members for 2021 were recognized at the association ’s annual meeting, which was held virtually April 8–10.Carmichael, UCLA ’s Frances Stark Professor of Neurology, is the chair of theneurology department in the David Geffen School of Medicine at UCLA and co-director of theEli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA.In his research, Carmichael s...
Source: UCLA Newsroom: Health Sciences - April 9, 2021 Category: Universities & Medical Training Source Type: news
Patient-Specific iPSC Model of a Genetic Vascular Dementia Syndrome Reveals Failure of Mural Cells to Stabilize Capillary Structures
Publication date: Available online 31 October 2019Source: Stem Cell ReportsAuthor(s): Joseph Kelleher, Adam Dickinson, Stuart Cain, Yanhua Hu, Nicola Bates, Adam Harvey, Jianzhen Ren, Wenjun Zhang, Fiona C. Moreton, Keith W. Muir, Christopher Ward, Rhian M. Touyz, Pankaj Sharma, Qingbo Xu, Susan J. Kimber, Tao WangSummaryCADASIL (cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy) is the most common form of genetic stroke and vascular dementia syndrome resulting from mutations in NOTCH3. To elucidate molecular mechanisms of the condition and identify drug targets, we established a pa...
Source: Stem Cell Reports - November 2, 2019 Category: Stem Cells Source Type: research
Stem cell factor and granulocyte colony-stimulating factor promote brain repair and improve cognitive function through VEGF-A in a mouse model of CADASIL.
This study provides novel insight into the involvement of VEGF/VEGF-A in the pathogenesis of CADASIL and sheds light on the mechanism underlying the SCF+G-CSF-enhanced brain repair in CADASIL.
PMID: 31376480 [PubMed - as supplied by publisher]
Source: Neurobiology of Disease - July 30, 2019 Category: Neurology Authors: Ping S, Qiu X, Kyle M, Hughes K, Longo J, Zhao LR Tags: Neurobiol Dis Source Type: research
Phagocytosis in the Brain: Homeostasis and Disease
Conclusions and Perspectives
In this review we have summarized the critical role phagocytosis plays in both CNS homeostasis and disease. While much progress has been made in recent years, many unanswered questions remain. How phagocytosis in the CNS is influenced by numerous factors, such as microenvironment or phagocytic target, have yet to be fully resolved. Additionally, the utilization of novel technologies, including in vivo imaging techniques (217), iPSC-derived microglia (213) and high-throughput screens (66), will likely contribute to further identification of phagocytic pathways and consequences of phagocytosis w...
Source: Frontiers in Immunology - April 15, 2019 Category: Allergy & Immunology Source Type: research
