Stem cell factor and granulocyte colony-stimulating factor promote brain repair and improve cognitive function through VEGF-A in a mouse model of CADASIL.

This study provides novel insight into the involvement of VEGF/VEGF-A in the pathogenesis of CADASIL and sheds light on the mechanism underlying the SCF+G-CSF-enhanced brain repair in CADASIL. PMID: 31376480 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/31376480?dopt=Abstract

Source: Neurobiology of Disease - July 30, 2019 Category: Neurology Authors: Ping S, Qiu X, Kyle M, Hughes K, Longo J, Zhao LR Tags: Neurobiol Dis Source Type: research