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Specialty: Gastroenterology
Condition: Bleeding

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Total 54 results found since Jan 2013.

Risk of Stroke in Liver Cirrhosis: A Systematic Review and Meta-Analysis
Conclusions: Stroke is uncommon in cirrhotic patients. However, considering a positive relationship of liver cirrhosis with subarachnoid and intracranial hemorrhage, the prophylactic strategy may be selectively adopted in cirrhotic patients.
Source: Journal of Clinical Gastroenterology - December 7, 2019 Category: Gastroenterology Tags: LIVER, PANCREAS & BILIARY TRACT: Original Articles Source Type: research

Risk score to predict gastrointestinal bleeding after acute ischemic stroke
Conclusion: The AIS-GIB score is a valid clinical grading scale to predict in-hospital GIB after AIS. Further studies on the effect of the AIS-GIB score on reducing GIB and improving outcome after AIS are warranted.
Source: BMC Gastroenterology - July 25, 2014 Category: Gastroenterology Authors: Ruijun JiHaipeng ShenYuesong PanPenglian WangGaifen LiuYilong WangHao LiAneesh SinghalYongjun Wang Source Type: research

Comparison of bleeding following gastrointestinal endoscopic biopsy in patients treated with and without direct oral anticoagulants
Conclusions The PS analyses showed no significant differences in complications following gastrointestinal endoscopic biopsy between DOAC users and non-users. These results suggest the safety of endoscopic biopsy without DOAC withdrawal although the need for careful hemostasis remains. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents  |  Abstract  |  open access Full text
Source: Endoscopy International Open - January 13, 2023 Category: Gastroenterology Authors: Konish, Takaaki Ono, Sachiko Okada, Akira Matsui, Hiroki Tanabe, Masahiko Seto, Yasuyuki Yasunaga, Hideo Tags: Original article Source Type: research

Adverse events requiring hospitalization within 30 days after outpatient screening and nonscreening colonoscopies
Conclusions: This study provides further evidence of the safety of colonoscopy in routine practice with regard to delayed and non-GI AEs. Hospitalizations because of the investigated AEs were uncommon or rare for both screening and nonscreening colonoscopies.
Source: Gastrointestinal Endoscopy - February 15, 2013 Category: Gastroenterology Authors: Christian Stock, Peter Ihle, Andreas Sieg, Ingrid Schubert, Michael Hoffmeister, Hermann Brenner Tags: Clinical Endoscopy Source Type: research

Health systems organization for emergency care
Abstract: The increasing number of acute and severe digestive diseases presenting to hospital emergency departments, mainly related with an ageing population, demands an appropriate answer from health systems organization, taking into account the escalating pressure on cost reduction. However, patients expect and deserve a response that is appropriate, effective, efficient and safe. The huge variety of variables which can influence the evolution of such cases warranting intensive monitoring, and the coordination and optimization of a range of human and technical resources involved in the care of these high-risk patients, r...
Source: Best Practice and Research. Clinical Gastroenterology - October 1, 2013 Category: Gastroenterology Authors: Isabel Pedroto, Pedro Amaro, José Manuel Romãozinho Tags: Chapters Source Type: research

Su1162 Gastrointestinal Bleeding With Warfarin, Novel Oral Anticoagulants and Left Atrial Appendage Exclusion Device in Patients With Atrial Fibrillation: Network Meta-Analysis of Randomized Controlled Trials
Novel oral anticoagulants (NOAC) are extensively being used in atrial fibrillation (AF) patients for mitigating stroke risk as an alternative to warfarin. In those patients with higher bleeding risk, left atrial appendage exclusion devices are being used for decreasing stroke risk. We performed a network meta-analysis of all randomized controlled trials (RCT) to compare the relative efficacy of all these agents.
Source: Gastrointestinal Endoscopy - April 28, 2017 Category: Gastroenterology Authors: Avanija Buddam, Arun Kanmanthareddy, Sunil Dacha, Sandeep Mukherjee, Savio Reddymasu Tags: Sunday – ASGE poster Source Type: research

Novel Oral Anticoagulants and Gastrointestinal Bleeding: a Case for Cardiogastroenterology
With the rapidly evolving cardiology drug pipeline for treatment of acute coronary syndrome (ACS), gastroenterologists have witnessed the emergence of a new population of patients who are vulnerable to gastrointestinal (GI) bleeding: the chronic cardiac patient. ACS, causing myocardial infarction (MI) and unstable angina, and atrial fibrillation are the signature conditions of the chronic cardiac patient. The morbidity and mortality of ACS is significant. Chronic cardiac patients are prescribed complex antithrombotic therapy (CAT) (ie, aspirin [ASA] plus a thienopyridine, eg, clopidogrel [Plavix; Bristol-Myers Squibb/Sanof...
Source: Clinical Gastroenterology and Hepatology - January 23, 2013 Category: Gastroenterology Authors: Neena S. Abraham Tags: Comment From the Editor Source Type: research

What is the best strategy for successful bowel preparation under special conditions?
Abstract Adequate bowel preparation is important for successful colonoscopic examination. Several effective colonic cleansing agents are available and routinely prescribed, but each carries its own limitations and benefits from particular dosing regimens. The most frequently prescribed colonic cleansing agent, the polyethylene glycol (PEG) cathartic solution, suffers from low patient compliance in general, due to its unpalatable taste and smell coupled with the large ingested volumes required. However, PEG is preferred over other cathartics for use in individuals of advanced age, sufferers of chronic kidney diseas...
Source: World Journal of Gastroenterology : WJG - March 21, 2014 Category: Gastroenterology Authors: Lim YJ, Hong SJ Tags: World J Gastroenterol Source Type: research

Risk of Vascular Thrombotic Events Following Discontinuation of Antithrombotics After Peptic Ulcer Bleeding
Conclusions: Discontinuation of antithrombotics after peptic ulcer bleeding increases the risk of cardiovascular events. Therefore, caution should be taken when discontinuing antithrombotics after ulcer bleeding.
Source: Journal of Clinical Gastroenterology - March 9, 2016 Category: Gastroenterology Tags: ONLINE ARTICLES: Original Articles Source Type: research

Nonsteroidal Anti-inflammatory Drug and Aspirin-induced Peptic Ulcer Disease.
Abstract Despite decreasing Helicobacter pylori prevalence, the prevalence of peptic ulcer disease is increasing in the aged population, mainly due to increasing use of NSAIDs to manage pain and inflammation. In addition, low dose aspirin is employed as an anti-coagulant for those who have suffered or are at high risk of ischemic stroke and cardiovascular disease. However, NSAIDs and aspirin are injurious to mucosa of stomach and duodenum. NSAID-induced inhibition of mucosal prostaglandin synthesis is thought to be a major mechanism of gastrointestinal mucosal injury. The proportion of elderly has increased rapidl...
Source: Korean J Gastroenter... - June 19, 2016 Category: Gastroenterology Authors: Shim YK, Kim N Tags: Korean J Gastroenterol Source Type: research

Discharge hemoglobin and outcome in patients with acute nonvariceal upper gastrointestinal bleeding
Conclusions: In patients with acute upper gastrointestinal bleeding, a discharge Hb between 8 and 10 g/dL was linked to favorable outcomes on outpatient follow-up. Most patients recovered from anemia without any critical complication within 45 days after discharge. [...]© Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals:Table of contents  |  Abstract  |  open access Full text
Source: Endoscopy International Open - July 20, 2016 Category: Gastroenterology Authors: Lee, Jae Min Kim, Eun Sun Chun, Hoon Jai Hwang, Young-Jae Lee, Jae Hyung Kang, Seung Hun Yoo, In Kyung Kim, Seung Han Choi, Hyuk Soon Keum, Bora Seo, Yeon Seok Jeen, Yoon Tae Lee, Hong Sik Um, Soon Ho Kim, Chang Duck Tags: Original article Source Type: research

Duodenal Glomus Tumor: A Rare Cause of Upper GI Bleeding
An 88-year-old woman with a past medical history of hypertension and stroke presented with 1 week of progressive weakness, lethargy, and orthostasis. She denied abdominal pain, melena, or hematochezia. Initial vitals signs were unremarkable, and physical examination was notable only for small external hemorrhoids. Stool was positive for occult blood. Her hemoglobin was 7 g/dL; it had been 12.1 g/dL 7 months before the time of her presentation. The following day, an esophagogastroduodenoscopy was performed, which showed a probable 1.5 cm  × 1 cm submucosal mass in the duodenal bulb with oozing at the edges (Figure A).
Source: Clinical Gastroenterology and Hepatology - March 22, 2016 Category: Gastroenterology Authors: Nicholas P. Tarangelo, Kai Ha, Kevin S. Skole Tags: Electronic Image of the Month Source Type: research

Major Gastrointestinal Bleeding Often Is Caused by Occult Malignancy in Patients Receiving Warfarin or Dabigatran to Prevent Stroke and Systemic Embolism From Atrial Fibrillation
Gastrointestinal (GI) bleeding in patients receiving anticoagulation agents can be caused by occult malignancies. We investigated the proportions and features of major GI bleeding (MGIB) events related to occult GI cancers in patients receiving anticoagulation therapy.
Source: Clinical Gastroenterology and Hepatology - October 16, 2016 Category: Gastroenterology Authors: Kathryn F. Flack, Jay Desai, Jennifer M. Kolb, Prapti Chatterjee, Lars C. Wallentin, Michael Ezekowitz, Salim Yusuf, Stuart Connolly, Paul Reilly, Martina Brueckmann, John Ilgenfritz, James Aisenberg Source Type: research

Gastrointestinal Bleeding and Direct Oral Anticoagulants Amongst Patients With Atrial Fibrillation in the “Real World”
The pivotal aim of oral anticoagulation in atrial fibrillation (AF) is prevention of AF-related thromboembolic strokes. The vitamin K antagonists (eg, warfarin) have been the standard of care for many years, reducing both stroke and mortality rates by 64% and 26% respectively, compared with placebo/control.1 Approval and market release of direct oral anticoagulants (DOACs; also referred to as non-vitamin K antagonist oral anticoagulants2), such as dabigatran, rivaroxaban, apixaban, and edoxaban, have changed the landscape of thromboprophylaxis substantially.
Source: Gastroenterology - February 28, 2017 Category: Gastroenterology Authors: Micha ł Mazurek, Gregory Y.H. Lip Tags: Editorial Source Type: research

Gastrointestinal Bleeding With Oral Anticoagulation: Understanding the Scope of the Problem
Systemic anticoagulation with vitamin K antagonists or direct-acting oral anticoagulants (DOACs) remains the mainstay of therapy to attenuate the risk of stroke and systemic embolism in patients with nonvalvular atrial fibrillation (NVAF). Given more predictable pharmacology, use of fixed-dose regimens, and lack of need for routine drug monitoring, DOACs have enjoyed relatively high uptake and quickly have become integrated into clinical practice.1 Although these agents generally have a favorable index of safety in comparison with warfarin with a lower risk of intracranial hemorrhage, rates of major gastrointestinal (GI) b...
Source: Clinical Gastroenterology and Hepatology - January 13, 2017 Category: Gastroenterology Authors: Muthiah Vaduganathan, Deepak L. Bhatt Tags: Editorial Source Type: research