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Hemorrhagic stroke and anticoagulation in COVID-19
We present a retrospective study of 33 patients positive for COVID-19 with neuroimaging-documented ICH and examine anticoagulation use in this population.
Source: Journal of Stroke and Cerebrovascular Diseases - May 22, 2020 Category: Neurology Authors: Siddhant Dogra, Rajan Jain, Meng Cao, Seda Bilaloglu, David Zagzag, Sarah Hochman, Ariane Lewis, Kara Melmed, Katherine Hochman, Leora Horwitz, Steven Galetta, Jeffrey Berger Tags: Hemorrhagic stroke in COVID-19 Source Type: research

Stroke Care during the COVID-19 Pandemic: International Expert Panel Review
This study, prepared by a large international panel of stroke experts, assesses the rapidly growing research and personal experience with COVID-19 stroke and offers recommendations for stroke management in this challenging new setting: modifications needed for prehospital emergency rescue and hyperacute care; inpatient intensive or stroke units; posthospitalization rehabilitation; follow-up including at-risk family and community; and multispecialty departmental developments in the allied professions.Summary: The severe acute respiratory syndrome coronavirus 2 uses spike proteins binding to tissue angiotensin-converting enz...
Source: Cerebrovascular Diseases - March 23, 2021 Category: Neurology Source Type: research

Anticoagulation use and Hemorrhagic Stroke in SARS-CoV-2 Patients Treated at a New York Healthcare System
ConclusionWe observed an overall low rate of imaging-confirmed hemorrhagic stroke among patients hospitalized with COVID-19. Most hemorrhages in patients with COVID-19 infection occurred in the setting of therapeutic anticoagulation and were associated with increased mortality. Further studies are needed to evaluate the safety and efficacy of therapeutic anticoagulation in patients with COVID-19.
Source: Neurocritical Care - August 23, 2020 Category: Neurology Source Type: research

Cerebral venous thrombosis in patients with autoimmune disease, hematonosis or coronavirus disease 2019: Many familiar faces and some strangers
CONCLUSION: A systematic understanding of particular risk factors that should not be neglected when unconventional cerebral venous thrombosis occurs and for a scientific understanding of pathophysiological mechanisms, clinical diagnosis, and treatment, thus contributing to knowledge on special types of venous stroke.PMID:37365966 | DOI:10.1111/cns.14321
Source: CNS Neuroscience and Therapeutics - June 27, 2023 Category: Neuroscience Authors: Yifan Zhou Huimin Jiang Huimin Wei Xuechun Xiao Lu Liu Xunming Ji Chen Zhou Source Type: research

Anticoagulants for people hospitalised with COVID-19
CONCLUSIONS: When compared to a lower-dose regimen, higher-dose anticoagulants result in little to no difference in all-cause mortality and increase minor bleeding in people hospitalised with COVID-19 up to 30 days. Higher-dose anticoagulants possibly reduce pulmonary embolism, slightly increase major bleeding, may result in little to no difference in hospitalisation time, and may result in little to no difference in deep vein thrombosis, stroke, major adverse limb events, myocardial infarction, atrial fibrillation, or thrombocytopenia. Compared with no treatment, anticoagulants may reduce all-cause mortality but the evide...
Source: Cochrane Database of Systematic Reviews - March 4, 2022 Category: General Medicine Authors: Ronald Lg Flumignan Vinicius T Civile J éssica Dantas de Sá Tinôco Patricia If Pascoal Libnah L Areias Charbel F Matar Britta Tendal Virginia Fm Trevisani Álvaro N Atallah Luis Cu Nakano Source Type: research

Outcomes of extracorporeal membrane oxygenation in acute respiratory distress syndrome due to COVID ‐19: The lessons learned from the first wave of COVID‐19
ConclusionsBased on our experience, ECMO can improve refractory ARDS due to COVID ‐19 in select patients. Proper control of bacterial infections during COVID‐19 immunomodulation therapy may be critical to improving survival.
Source: Journal of Cardiac Surgery - March 19, 2021 Category: Cardiovascular & Thoracic Surgery Authors: Cameron Blazoski, Michael Baram, Hitoshi Hirose Tags: ORIGINAL ARTICLE Source Type: research

Unexplained arterial thrombosis: approach to diagnosis and treatment
We present a structured approach to diagnosis with consideration of common causes, including atherosclerosis and embolism, as well as uncommon causes, including medications and substances, vascular and anatomic abnormalities, systemic disorders, and thrombophilias. We highlight areas of management that have evolved within the past 5 years, including the use of dual-pathway inhibition in atherosclerotic disease, antithrombotic therapy selection in embolic stroke of undetermined source and left ventricular thrombus, the role of closure of patent foramen ovale for secondary stroke prevention, and the thrombotic potential of c...
Source: Atherosclerosis - December 10, 2021 Category: Cardiology Authors: Jori E May Stephan Moll Source Type: research

Venovenous extracorporeal membrane oxygenation for coronavirus disease 2019 patients: A systematic review and meta-analysis
CONCLUSION: Although COVID-19 patients may have a higher risk of bleeding, hemorrhagic stroke, and acute kidney injury during ECMO therapy, the survival rate was more than half of the cases. Our data may support the application of VV-ECMO in COVID-19 patients.PMID:35608047 | DOI:10.1177/02676591221104302
Source: Perfusion - May 24, 2022 Category: Cardiovascular & Thoracic Surgery Authors: Kerong Zhai Xu Xu Pengbin Zhang Shilin Wei Jian Li Xiangyang Wu Bingren Gao Yanhua Zhang Yongnan Li Source Type: research

Things I know to be true 1 – We are all walking miracles
Back when I was child I genuinely believed that when my mother kissed my knee to make it better, she did actually do that. And as I grew older although that belief faded away in the light of the obvious ‘fact’ of the medical model, it never truly disappeared. Time and again I would reflect on what it meant to be healthy and when my own health challenges began in my mid-teens, some part of me always knew that my mother’s kiss held meaning. I remember being 16 years old and just about to sit ‘O’ levels, as they were then. I had been having a period for what must have been weeks and I was tired a...
Source: The Hysterectomy Association - June 25, 2020 Category: OBGYN Authors: Linda Parkinson-Hardman Tags: Health life miracle Source Type: news

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