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Total 38 results found since Jan 2013.

Cardioversion of Atrial Fibrillation with Acupuncture
Conclusions: Acupuncture appears to be solely responsible for the conversion of atrial fibrillation to sinus rhythm in this case, as no β-blockers, calcium channel blockers, or antiarrhythmic medicines were administered before the return to sinus rhythm. The antiarrhythmic effect noted may be from centrally mediated autonomic effects or additional mechanisms. Further study will help to define the role of acupuncture in the management of acute arrhythmias.PMID:34239665 | PMC:PMC8236297 | DOI:10.1089/acu.2021.0022
Source: Acupuncture in Medicine - July 9, 2021 Category: Complementary Medicine Authors: Stephen Olex Source Type: research

Platelet function, coagulation and fibrinolysis in patients with previous coronary and cerebrovascular ischemic events
CONCLUSION: Platelet aggregability, coagulation and endogenous fibrinolysis showed similar results among CAD patients with and without previous IS/TIA. Therefore, it remains necessary to identify other targets to explain the higher bleeding risk presented by these patients.
Source: Clinics - September 26, 2019 Category: General Medicine Source Type: research

Using Dental Pulp Stem Cells for Stroke Therapy
Conclusion and Future Perspectives Stem cell-based therapy is a promising alternative for stroke treatment. While stem cells from different sources, including induced PSC, ESC, MSC, and NSC, have been investigated, using NSC and enhancing the natural mechanisms is most appropriate for brain repair. In preclinical models of stroke, stem cell transplantation has led to positive outcomes through a variety of cellular and molecular mechanisms, many being mediated by the array of beneficial factors produced by the cells. Recent advances in cellular reprogramming have provided alternative sources of NSC to be investigated, allo...
Source: Frontiers in Neurology - April 28, 2019 Category: Neurology Source Type: research

Low Serum Calcium and Magnesium Levels and Rupture of Intracranial Aneurysms Brief Report
Conclusions—In this large case–control study, hypocalcemia and hypomagnesemia at diagnosis were significantly associated with ruptured aneurysms. Impaired hemostasis caused by hypocalcemia and hypomagnesemia may explain this association.
Source: Stroke - June 25, 2018 Category: Neurology Authors: Anil Can, Robert F. Rudy, Victor M. Castro, Dmitriy Dligach, Sean Finan, Sheng Yu, Vivian Gainer, Nancy A. Shadick, Guergana Savova, Shawn Murphy, Tianxi Cai, Scott T. Weiss, Rose Du Tags: Risk Factors, Cerebral Aneurysm Brief Reports Source Type: research

CK2{beta} regulates thrombopoiesis and Ca2+-triggered platelet activation in arterial thrombosis
Platelets, anucleated megakaryocyte (MK)-derived cells, play a major role in hemostasis and arterial thrombosis. Although protein kinase casein kinase 2 (CK2) is readily detected in MKs and platelets, the impact of CK2-dependent signaling on MK/platelet (patho-)physiology has remained elusive. The present study explored the impact of the CK2 regulatory β-subunit on platelet biogenesis and activation. MK/platelet-specific genetic deletion of CK2β (ck2β–/–) in mice resulted in a significant macrothrombocytopenia and an increased extramedullar megakaryopoiesis with an enhanced proportion of prematur...
Source: Blood - December 21, 2017 Category: Hematology Authors: Münzer, P., Walker-Allgaier, B., Geue, S., Langhauser, F., Geuss, E., Stegner, D., Aurbach, K., Semeniak, D., Chatterjee, M., Gonzalez Menendez, I., Märklin, M., Quintanilla-Martinez, L., Salih, H. R., Litchfield, D. W., Buchou, T., Kleins Tags: Platelets and Thrombopoiesis, Thrombosis and Hemostasis Source Type: research

No-touch ’ heart bypass surgery reduces strokes
Four surgical methods of coronary artery bypass grafting with increasing degrees of aortic manipulation. Percentages pictured represent the relative decrease in risk of perioperative stroke using anOPCABG compared to the other techniques. [Image from the researchers]]A recent study from the University of Sydney and Sydney Heart and Lung Surgeons has shown that a new “no-touch” beating heart bypass surgery technique has reduced post-operative stroke by 78%. The procedure, known as an OPCABG, also reduced post-operative mortality by 50% compared to traditional coronary artery bypass grafting. It reduced renal failure by ...
Source: Mass Device - May 17, 2017 Category: Medical Devices Authors: Danielle Kirsh Tags: Cardiovascular CABG MedTech Sydney Heart and Lung Surgeons University of Sydney Source Type: news

The risk of lower gastrointestinal bleeding in low ‐dose aspirin users
ConclusionsThe risk of LGIB was higher in low‐dose aspirin users than in aspirin nonusers in this nationwide cohort. Low‐dose aspirin, NSAIDs, steroids, SSRIs, PPIs and H2RAs were independent risk factors for LGIB.
Source: Alimentary Pharmacology and Therapeutics - April 27, 2017 Category: Drugs & Pharmacology Authors: W. ‐C. Chen, K.‐H. Lin, Y.‐T. Huang, T.‐J. Tsai, W.‐C. Sun, S.‐K. Chuah, D.‐C. Wu, P.‐I. Hsu Tags: Original Article Source Type: research

What to do when blood test results are not quite “normal”
Picture this: you’re reading the results of your recent bloodwork, and you notice some numbers are teetering on the edge of the normal range. Should you be concerned? “It’s tricky, because in some tests, a borderline result makes no difference. In others, it might indicate an important change in health that we need to follow or act on,” says geriatrician Dr. Suzanne Salamon, assistant professor at Harvard Medical School. About normal ranges and interpreting the numbers When you look at a printout of your lab results, you’ll find the normal ranges for each blood test next to your personal results. For example, if ...
Source: New Harvard Health Information - June 2, 2016 Category: Consumer Health News Authors: Heidi Godman Tags: Tests and procedures blood test Source Type: news

What to do when blood test results not quite “normal”
Picture this: you’re reading the results of your recent bloodwork, and you notice some numbers are teetering on the edge of the normal range. Should you be concerned? “It’s tricky, because in some tests, a borderline result makes no difference. In others, it might indicate an important change in health that we need to follow or act on,” says geriatrician Dr. Suzanne Salamon, assistant professor at Harvard Medical School. About normal ranges and interpreting the numbers When you look at a printout of your lab results, you’ll find the normal ranges for each blood test next to your personal results. For example, if ...
Source: New Harvard Health Information - June 2, 2016 Category: Consumer Health News Authors: Heidi Godman Tags: Tests and procedures blood test Source Type: news

Partially Defective Store Operated Calcium Entry and Hem(ITAM) Signaling in Platelets of Serotonin Transporter Deficient Mice
Conclusion Although secreted platelet 5-HT does not appear to play a crucial role in the development of reperfusion injury after stroke, it is essential to amplify the second phase of platelet activation through SOCE and plays an important role in thrombus stabilization.
Source: PLoS One - January 22, 2016 Category: Biomedical Science Authors: Karen Wolf et al. Source Type: research