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Condition: Kidney Transplantation
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Total 816 results found since Jan 2013.
Stimulator of interferon genes (STING): Key therapeutic targets in ischemia/reperfusion injury
Biomed Pharmacother. 2023 Sep 10;167:115458. doi: 10.1016/j.biopha.2023.115458. Online ahead of print.ABSTRACTThe Stimulator of Interferon Genes (STING) is predominantly expressed in immune cells, including macrophages, natural killer cells, dendritic cells, and T cells, functioning as a pattern recognition receptor. STING activation upon detecting cytosolic DNA released from damaged cells initiates downstream pathways, leading to the production of inflammatory cytokines such as IFNs, IL-6, and TNF-α. Dysregulated STING activation has been implicated in inflammatory and metabolic diseases. Ischemia/reperfusion injury (I/R...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - September 12, 2023 Category: Drugs & Pharmacology Authors: Juan Lv Xuanxuan Zhu Chunlei Xing Yuhong Chen Huihui Bian Heng Yin Xiaofeng Gu Li Su Source Type: research
Screening and Management of Coronary Artery Disease in Kidney Transplant Candidates
Diagnostics (Basel). 2023 Aug 20;13(16):2709. doi: 10.3390/diagnostics13162709.ABSTRACTCardiovascular disease (CVD) is a major cause of morbidity and mortality in patients with chronic kidney disease (CKD), especially in end-stage renal disease (ESRD) patients and during the first year after transplantation. For these reasons, and due to the shortage of organs available for transplant, it is of utmost importance to identify patients with a good life expectancy after transplant and minimize the transplant peri-operative risk. Various conditions, such as severe pulmonary diseases, recent myocardial infarction or stroke, and ...
Source: Atherosclerosis - August 26, 2023 Category: Cardiology Authors: Giuseppe Vadal à Chiara Alaimo Giancarlo Buccheri Luca Di Fazio Leandro Di Caccamo Vincenzo Sucato Manlio Cipriani Alfredo Ruggero Galassi Source Type: research
Acute Kidney Injury as a Leading Cause of Papal Deaths in the Years 1277 to 2005: A Review of 21 Cases
CONCLUSIONS: Sepsis-associated acute kidney injury, a syndrome with a complex pathogenesis and poor prognosis, which is far from being fully understood, contributed to a high number of papal deaths.PMID:37496352 | DOI:10.6002/ect.IAHNCongress.20
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - July 27, 2023 Category: Transplant Surgery Authors: Natale Gaspare De Santo Carmela Bisaccia Luca Salvatore De Santo Source Type: research
Global Economic Burden Associated with Chronic Kidney Disease: A Pragmatic Review of Medical Costs for the Inside CKD Research Programme
CONCLUSION: Globally, CKD carries a significant economic burden, which increases substantially with increasing disease severity. We identified significant gaps in published costs and inconsistent costing definitions. Cost-effective interventions that target primary prevention and disease progression are essential to reduce CKD burden. Our results can be used to guide cost collection and facilitate better comparisons across countries/regions to inform healthcare policy.PMID:37493856 | DOI:10.1007/s12325-023-02608-9
Source: Adv Data - July 26, 2023 Category: Epidemiology Authors: Vivekanand Jha Saeed M G Al-Ghamdi Guisen Li Mai-Szu Wu Panagiotis Stafylas Lise Retat Joshua Card-Gowers Salvatore Barone Claudia Cabrera Juan Jose Garcia Sanchez Source Type: research
Angiotensin-converting enzyme inhibitors and angiotensin receptor blockers for adults with early (stage 1 to 3) non-diabetic chronic kidney disease
CONCLUSIONS: There is currently insufficient evidence to determine the effectiveness of ACEi or ARB in patients with stage 1 to 3 CKD who do not have DM. The available evidence is overall of very low certainty and high risk of bias. We have identified an area of large uncertainty for a group of patients who account for most of those diagnosed as having CKD.PMID:37466151 | DOI:10.1002/14651858.CD007751.pub3
Source: Cochrane Database of Systematic Reviews - July 19, 2023 Category: General Medicine Authors: Tess E Cooper Claris Teng David J Tunnicliffe Brydee A Cashmore Giovanni Fm Strippoli Source Type: research
Outcomes of Combined Heart-Kidney Transplantation in Older Recipients
CONCLUSION: Combined HKT is increasing in older recipients, and advanced age ≥65 should not preclude HKT.PMID:37396466 | PMC:PMC10314816 | DOI:10.1155/2023/4528828
Source: Cardiology Research and Practice - July 3, 2023 Category: Cardiology Authors: Curry Sherard Vineeth Sama Jennie H Kwon Khaled Shorbaji Lauren V Huckaby Brett A Welch Chakradhari Inampudi Ryan J Tedford Arman Kilic Source Type: research
