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Total 138 results found since Jan 2013.
Trends in volume-regulated anion channel (VRAC) research: visualization and bibliometric analysis from 2014 to 2022
Conclusion: The aim of this bibliometric analysis is to provide an overall perspective for research on VRAC. VRAC has become a topic of increasing interest, and our analysis shows that it continues to be a prominent area. This study offers insights into the investigation of VRAC channel and may guide researchers in identifying new directions for future research.PMID:37538172 | PMC:PMC10394876 | DOI:10.3389/fphar.2023.1234885
Source: Atherosclerosis - August 4, 2023 Category: Cardiology Authors: Tianbao Liu Yin Li Dawei Wang Tobias Stauber Jiajun Zhao Source Type: research
Incidental findings on FDG-PET/CT in large vessel vasculitis
This study aims to determine the number and type of incidental findings detected on positron emission tomography (PET)/CT in a cohort of patients with large vessel vasculitis (LVV). Reports from PET/CT studies along with the medical charts of a cohort of patients with LVV from a Rheumatology clinic in Edmonton, Alberta, Canada, were retrospectively reviewed. Incidental findings from PET/CT, along with follow-up studies and their diagnosis were documented. The data was analyzed with descriptive statistics. The disease activity of 40 patients, with an average age of 65.8 years, was investigated using PET/CT. A statisticall...
Source: Clinical Rheumatology - July 17, 2023 Category: Rheumatology Source Type: research
Stroke death in patients receiving radiation for head and neck cancer in the modern era
CONCLUSIONS: While radiotherapy for head and neck cancer increases the hazard of stroke death, this is reduced in the modern era and remains a very small absolute risk.PMID:37397363 | PMC:PMC10313411 | DOI:10.3389/fonc.2023.1111764
Source: Cancer Control - July 3, 2023 Category: Cancer & Oncology Authors: Sara J Hardy Sanjukta Bandyopadhyay Hongmei Yang Annalynn Williams Abdi Gudina Michael A Cummings Hong Zhang Deepinder P Singh Yuhchyau Chen Nimish A Mohile Michelle C Janelsins Michael T Milano Source Type: research
Risk of Cardiovascular Events Among Patients With Head and Neck Cancer
This cohort study examines cardiovascular risk profiles, incident stroke, myocardial infarction, and mortality in US veterans with head and neck squamous cell carcinoma.
Source: JAMA Otolaryngology - Head and Neck Surgery - June 22, 2023 Category: ENT & OMF Source Type: research
Stroke death in patients receiving radiation for head and neck cancer in the modern era
ConclusionsWhile radiotherapy for head and neck cancer increases the hazard of stroke death, this is reduced in the modern era and remains a very small absolute risk.
Source: Frontiers in Oncology - June 15, 2023 Category: Cancer & Oncology Source Type: research
Clinical Symptoms, Laboratory Parameters and Long-Term Follow-up in a National DADA2 Cohort
In conclusion, this cohort describes the clinical, genetic and laboratory findings of 29 Dutch DADA2 patients. We describe the occurrence of HLH as a life-threatening disease complication and report a relatively high incidence of malignancies and mortality.
Source: Journal of Clinical Immunology - June 5, 2023 Category: Allergy & Immunology Source Type: research
SNHG11 ：A New Budding Star in Tumors and Inflammatory Diseases
CONCLUSION: LncRNA SNHG11 can serve as an early diagnostic biomarker, therapeutic target, and prognostic indicator in various diseases, particularly tumors. SNHG11 plays a crucial role in the occurrence and development of tumors and inflammatory diseases through various mechanisms, which has significant implications for clinical diagnosis and treatment.PMID:37165588 | DOI:10.2174/1389557523666230509122402
Source: Mini Reviews in Medicinal Chemistry - May 11, 2023 Category: Chemistry Authors: Yinxin Wu Source Type: research
Differentially Expressed Genes Analysis in the Human Small Airway Epithelium of Healthy Smokers Shows Potential Risks of Disease Caused by Oxidative Stress and Inflammation and the Potentiality of Astaxanthin as an Anti-Inflammatory Agent
This study aims to observe differentially expressed genes (DEGs) in the human small airway epithelium of smokers compared to genes whose expression changes due to astaxanthin (AST) treatment, an antioxidant compound that can modulate Nrf2. Gene expression data that was stored in the GEO browser (GSE 11952) was analyzed using GEO2R to search for DEG among smokers and nonsmokers subject. DEG was further compared to those genes whose expression changes due to astaxanthin treatment (AST) that were obtained from the Comparative Toxicogenomics Database (CTD; https://ctdbase.org/). DEG (p < 0.05) analysis result shows that the...
Source: International Journal of Inflammation - March 13, 2023 Category: Allergy & Immunology Authors: Irandi Putra Pratomo Aryo Tedjo Dimas R Noor None Rosmalena Source Type: research
Janssen Data at ASCO GU Support Ambition to Transform Treatment of Prostate and Bladder Cancer Through Precision Medicine and Early Intervention
RARITAN, N.J., February 13, 2023 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced plans to present more than 20 abstracts featuring seven oncology therapies from its robust portfolio and pipeline at the annual American Society of Clinical Oncology (ASCO) Genitourinary (GU) Cancers Symposium, taking place in San Francisco on February 16-18. Building on more than a decade of leadership in the development of medicines for people diagnosed with GU cancers, Janssen will present data demonstrating its ambition to advance patient-centered treatment through precision medicine, real-world evidence a...
Source: Johnson and Johnson - February 13, 2023 Category: Pharmaceuticals Tags: Latest News Source Type: news
Clinical characteristics of pancreatic and biliary tract cancers in Lynch syndrome: A retrospective analysis from the Finnish National Lynch Syndrome Research Registry
ConclusionAlthough the survival of LS patients with PC or BTC is better than in sporadic cancers, it is still poor and may be reflected by the relatively higher surgical resectability accounted for by the earlier age of onset. More studies on analyses of the molecular and immune profile, screening, and management of LS-associated pancreaticobiliary cancers are warranted.
Source: Frontiers in Oncology - February 1, 2023 Category: Cancer & Oncology Source Type: research
Systematic analysis of brain and skull ischemic injury expression profiles reveals associations of the tumor immune microenvironment and cell death with ischemic stroke
ConclusionThis systematic analysis not only helps in the understanding of the changes in the gene expression profiles of both the brain and skull with ischemic injury but also reveals the association of the tumor immune microenvironment and cell death with ischemic stroke.
Source: Frontiers in Immunology - December 20, 2022 Category: Allergy & Immunology Source Type: research
