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Total 421 results found since Jan 2013.

Health Transition in Iran toward Chronic Diseases Based on Results of Global Burden of Disease 2010.
CONCLUSIONS: Time trend information presented in this paper can be used to evaluate problems and policies specific to medical conditions or risk factors. Despite recent improvements, implementing policies to reduce the number of deaths and years of life lost due to road traffic injury remains the highest priority for Iranian policymakers. Immediate action by Iranian researchers is required to match Iran's decreasing mortality rate due to liver and stomach cancers to a rate comparable to the global level. Prevention and treatment plans for mental disorders, such as major depressive disorder, anxiety disorder, and particular...
Source: Archives of Iranian Medicine - May 1, 2014 Category: Middle East Health Authors: Naghavi M, Shahraz S, Sepanlou SG, Dicker D, Naghavi P, Pourmalek F, Mokdad A, Lozano R, Vos T, Asadi-Lari M, Sayyari AA, Murray CJ, Forouzanfar MH Tags: Arch Iran Med Source Type: research

The Atrial Fibrillation Ablation Pilot Study: an European Survey on Methodology and results of catheter ablation for atrial fibrillation conducted by the European Heart Rhythm Association
Conclusion The AFib Ablation Pilot Study provided crucial information on the epidemiology, management, and outcomes of catheter ablation of AFib in a real-world setting. The methods used to assess the success of the procedure appeared at least suboptimal. Even in this context, the 12-month success rate appears to be somewhat lower to the one reported clinical trials.
Source: European Heart Journal - June 7, 2014 Category: Cardiology Authors: Arbelo, E., Brugada, J., Hindricks, G., Maggioni, A. P., Tavazzi, L., Vardas, P., Laroche, C., Anselme, F., Inama, G., Jais, P., Kalarus, Z., Kautzner, J., Lewalter, T., Mairesse, G. H., Perez-Villacastin, J., Riahi, S., Taborsky, M., Theodorakis, G., Tri Tags: Arrhythmia/electrophysiology Source Type: research

Should they have a percutaneous endoscopic gastrostomy? The importance of assessing decision-making capacity and the central role of a multidisciplinary team.
Abstract Decisions about percutaneous endoscopic gastrostomy (PEG) can be clinically and ethically challenging, particularly when patients lack decision-making capacity. As the age of the UK population rises, with the associated increase in prevalence of dementias and neurodegenerative diseases, it is becoming an increasingly important issue for clinicians. The recent review and subsequent withdrawal of the Liverpool Care Pathway highlighted feeding as a particular area of concern. The authors undertook a 1-year retrospective review of individuals referred to the feeding issues multidisciplinary team (FIMDT) at Ad...
Source: Clinical Medicine - June 1, 2014 Category: Journals (General) Authors: Clarke G, Galbraith S, Woodward J, Holland A, Barclay S Tags: Clin Med Source Type: research

Aspirin risks in perspective: A comparison against marathon running
Aspirin has public health potential to reduce the risk of ischaemic vascular events and sporadic cancer. One objection to the wider use of aspirin for primary prevention, however, is the undesirable effects of the medicine, which include increasing risk of bleeding and haemorrhagic stroke. Marathons also carry risks of serious events such as cardiac arrests and sudden death. Based on epidemiological estimates, a person running a marathon might be 20 to 100 times more likely to end up in hospital than a person who is taking an aspirin tablet. Yet the cumulative risk of daily aspirin use for primary prophylaxis may be import...
Source: Health Education Journal - June 10, 2014 Category: Health Management Authors: Morgan, G. Tags: Short Report Source Type: research

Talon noir: paring can eliminate the need for a biopsy
Introduction Talon noir (black heel or calcaneal petechiae) is a benign condition that appears as an asymmetric brown-black epidermal macule on the heel or elsewhere on the plantar foot. Punctate papillary dermal haemorrhages extend into the subcorneal space following shearing forces in an area of recurrent or sudden trauma.1 These lesions can mimic melanoma and haemorrhagic viral warts, especially in cases where there is no history of trauma. If the diagnosis of talon noir is considered, simple bedside tests can obviate the need for a biopsy to exclude malignant melanoma or unnecessary treatment for a presumed viral wart....
Source: Postgraduate Medical Journal - November 26, 2014 Category: Journals (General) Authors: Googe, A. B., Schulmeier, J. S., Jackson, A. R., Brodell, R. T. Tags: General practice / family medicine, Drugs: cardiovascular system, Pain (neurology), Stroke, Skin cancer, Screening (oncology), Radiology, Dermatology, Surgical diagnostic tests, General surgery, Epidemiology Images in medicine Source Type: research

ANCA associated vasculitis - Evaluation of diagnosis, treatment and outcome in a group of 68 patients
Conclusions: Significant differences exist between GPA and MPA at the initial presentation that can predict the evolution of the disease. The management of patients with ANCA-associated vasculitides is difficult and marked by the adverse effects of the therapy.
Source: European Respiratory Journal - December 23, 2014 Category: Respiratory Medicine Authors: Belaconi, I., Toma, C., Stancu, S., Dumitrache-Rujinski, S., Tudose, C., Croitoru, A., Grigoriu, L., Leonte, D., Magheran, E., Bogdan, M. Tags: 1.13 Clinical Problems - Other Source Type: research

Clinical Outcomes of Metastatic Intra-cerebral Hemorrhage and Role of Acute Radiotherapy (P3.077)
CONCLUSIONS: Early recognition of metastatic disease as the etiology of ICH is important, particularly when it is the presenting manifestation. Despite the overall poor prognosis of metastatic cancer, early radiotherapy may increase survival and offer quality of life in selected group of patients. A larger case series is needed.Disclosure: Dr. Afzal has nothing to disclose. Dr. Mendoza has nothing to disclose. Dr. Latorre has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Afzal, U., Mendoza, M., Latorre, J. Tags: Cerebrovascular Disease and Interventional Neurology: Hemorrhagic and Ischemic Stroke Source Type: research

Up-regulation of VCAM1 Relates to Neuronal Apoptosis After Intracerebral Hemorrhage in Adult Rats.
Abstract Vascular cell adhesion molecule 1 (VCAM1) is a member of the Immunoglobulin superfamily and encodes a cell surface sialoglycoprotein expressed in cytokine-activated endothelium. This type I membrane protein mediates leukocyte-endothelial cell adhesion, facilitates the downstream signaling, and may play a role in the development of artherosclerosis and rheumatoid arthritis. Accumulating evidence has demonstrated that VCAM1 exerts an anti-apoptotic effect in several tumor tissues such as ovarian cancer and breast cancer. Intracerebral hemorrhage (ICH) is the second most common subtype of stroke with high mo...
Source: Neurochemical Research - April 14, 2015 Category: Neuroscience Authors: Zhang D, Yuan D, Shen J, Yan Y, Gong C, Gu J, Xue H, Qian Y, Zhang W, He X, Yao L, Ji Y, Shen A Tags: Neurochem Res Source Type: research

Cost‐effectiveness of Quantitative Pretest Probability Intended to Reduce Unnecessary Medical Radiation Exposure in Emergency Department Patients With Chest Pain and Dyspnea
ConclusionsWidespread use of a combined qPTP for both ACS and PE has the potential to decrease costs by reducing diagnostic testing, while improving most long‐term outcomes in emergency patients with chest pain and dyspnea.
Source: Academic Emergency Medicine - April 21, 2015 Category: Emergency Medicine Authors: Jennifer L. Troyer, Alan E. Jones, Nathan I. Shapiro, Alice M. Mitchell, Ian Hewer, Jeffrey A. Kline Tags: Original Contribution Source Type: research

Cost-effectiveness of Quantitative Pretest Probability Intended to Reduce Unnecessary Medical Radiation Exposure in Emergency Department Patients With Chest Pain and Dyspnea.
CONCLUSIONS: Widespread use of a combined qPTP for both ACS and PE has the potential to decrease costs by reducing diagnostic testing, while improving most long-term outcomes in emergency patients with chest pain and dyspnea. PMID: 25899550 [PubMed - as supplied by publisher]
Source: Accident and Emergency Nursing - April 21, 2015 Category: Emergency Medicine Authors: Troyer JL, Jones AE, Shapiro NI, Mitchell AM, Hewer I, Kline JA Tags: Acad Emerg Med Source Type: research

MassDevice.com +3 | The top 3 medtech stories for August 17, 2015
Say hello to MassDevice +3, a bite-sized view of the top three medtech stories of the day. This feature of MassDevice.com’s coverage highlights our 3 biggest and most influential stories from the day’s news to make sure you’re up to date on the headlines that continue to shape the medical device industry.   3. CooperSurgical pays $47m for IVF screener Reprogenetics Cooper Cos. CooperSurgical subsidiary acquired in-vitro fertilization screening company Reprogenetics for nearly $47 million. Livingston, N.J.-based Reprogenetics offers pre-implantation genetic screening and diagnosis for in vitro fertil...
Source: Mass Device - August 17, 2015 Category: Medical Equipment Authors: MassDevice Tags: News Well Plus 3 Source Type: news

Risk of type 2 diabetes mellitus in female breast cancer patients treated with morphine: a retrospective population-based time-dependent cohort study
A key element of the palliative care of cancer patients is the management of chronic pain [1]. Opioids continue to be a mainstay in the management of cancer pain in all treatment guidelines [2], and morphine is regarded as the “gold standard” [3–6]. Considered as broad-spectrum analgesics, opioids have multiple side effects and potential complications [7]. Our previous studies indicated that morphine treatment is associated with subdural hemorrhage [8], pulmonary embolism [9], and acute coronary syndrome [10] in cancer patients, as well as increased stroke incidence in prostate cancer patients [11].
Source: Diabetes Research and Clinical Practice - October 12, 2015 Category: Endocrinology Authors: Szu-Pang Yang, Chih-Hsin Muo, I-Kuan Wang, Yen-Jung Chang, Shih-Wei Lai, Cynthia Wei-Sheng Lee, Donald E. Morisky Source Type: research

Fibroblast Growth Factor 23 and Incidence of Subarachnoid Hemorrhage: Nested Case-Control Study Brief Reports
Conclusions— High FGF23 was associated with increased risk of incident SAH in subjects from the general population. Further studies should elucidate whether FGF23 is a causal risk factor for SAH, or could be used in risk prediction.
Source: Stroke - October 26, 2015 Category: Neurology Authors: Soderholm, M., Engstrom, G. Tags: Cerebral Aneurysm, AVM, & Subarachnoid hemorrhage, Epidemiology Brief Reports Source Type: research

Hemodialysis with end-stage renal disease did not raise the risk of intracranial hemorrhage after a head injury
Conclusions: HD +ESRD did not increase the post-HI risk of ICH. Therefore, it may not be necessary to lower the threshold of head CT in HD +ESRD patients.
Source: Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine - October 28, 2015 Category: Emergency Medicine Authors: Hsin-Hung ChenChien-Chin HsuShih-Feng WengHung-Jung LinJhi-Joung WangHow-Ran GuoShih-Bin SuChien-Cheng HuangJiann-Hwa Chen Source Type: research

Lung Cancer and Exposure to Nitrogen Dioxide and Traffic: A Systematic Review and Meta-Analysis
Conclusion: We found consistent evidence of a relationship between NO2, as a proxy for traffic-sourced air pollution exposure, with lung cancer. Studies of lung cancer related to residential proximity to roadways and NOx also suggest increased risk, which may be attributable partly to air pollution exposure. The International Agency for Research on Cancer recently classified outdoor air pollution and particulate matter as carcinogenic (Group 1). These meta-analyses support this conclusion, drawing particular attention to traffic-sourced air pollution. Citation: Hamra GB, Laden F, Cohen AJ, Raaschou-Nielsen O, Brauer...
Source: EHP Research - November 2, 2015 Category: Environmental Health Authors: Sam Duvall Tags: Review November 2015 Source Type: research