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Total 564 results found since Jan 2013.

Measuring Ambulation, Motor, and Behavioral Outcomes with Poststroke Fluoxetine in Tanzania: The Phase II MAMBO Trial
Am J Trop Med Hyg. 2021 Dec 6:tpmd210653. doi: 10.4269/ajtmh.21-0653. Online ahead of print.ABSTRACTWe test the safety of fluoxetine postischemic stroke in sub-Saharan Africa. Adults with acute ischemic stroke, seen <14 days since new-onset motor deficits, were enrolled from November 2019 to October 2020 in a single-arm, open-label phase II trial of daily fluoxetine 20 mg for 90 days at Muhimbili National Hospital, Dar es Salaam, Tanzania. The primary outcome was safety with secondary outcomes of medication adherence and tolerability. About 34 patients were enrolled (11 were female; mean age 52.2 years, 65% < 60 year...
Source: Am J Trop Med Hyg - December 6, 2021 Category: Infectious Diseases Authors: Farrah Mateen Emmanuel Massawe Notburga Mworia Seif Ismail Dylan Rice Andre Vogel Boniface Kapina Novath Mukyanuzi Deus Buma Jef Gluckstein Michael Wasserman Susan Fasoli Faraja Chiwanga Kigocha Okeng'o Source Type: research

Association of chronic kidney disease with exposure to polycyclic aromatic hydrocarbons in the US population
This study aims to investigate the association between seven urinary PAH concentrations (1-hydroxynaphthalene, 2-hydroxynaphthalene, 3-hydroxyfluorene 2-hydroxyfluorene, 1-hydroxyphenanthrene, 1-hydroxypyrene, and 2 & 3-hydroxyphenanthrene) and CKD in the US adult population. A cross-sectional analysis using the 2015-2016 National Health and Nutrition Examination Survey (NHANES) dataset was conducted. CKD was defined with estimated glomerular filtration rate (eGFR) and albumin to creatinine ratio (ACR). Participants with an eGFR < 60 ml/min/1.73m2 or ACR > 30 mg/gm were considered to have CKD. A specialized compl...
Source: Environmental Science and Pollution Research International - November 25, 2021 Category: Environmental Health Authors: Humairat H Rahman Danielle Niemann Stuart H Munson-McGee Source Type: research

Anxiety, Depression, Psychological Symptoms, Negative Effects, and Other Symptoms of Nicotine Withdrawal
This case occurred in a 33-year-old man who has been smoking for 19 years. He had a pattern of consuming 14 cigarettes per day with 30 mg of nicotine intake and high tar levels. The level of tolerance for consumption of nicotine and tar per day is 10 to 15 mg. High cigarette consumption correlates with high nicotine consumption as well. Excessive nicotine consumption over a long period can lead to lung cancer, stroke, heart disease, chronic obstructive pulmonary disease, and psychological disorders.
Source: Addictive Disorders and Their Treatment - November 25, 2021 Category: Addiction Tags: Case Reports Source Type: research

Compound Developed at UArizona Health Sciences Provides Innovative Pain Relief
Digital media& downloads Compound Developed at UArizona Health Sciences Provides Innovative Pain Relief Researchers targeted a common sodium ion channel to reverse pain and saw positive results that could lead to a nonaddictive solution to treat pain. Today University of Arizona Health Sciencespain-relief-web.jpgHealthBIO5College of Medicine - TucsonExpertsResearch Media contact(s)Stacy Pigott University of Arizona Health Sciencesspigott@arizona.edu520-539-4152Researchers at the  University of Arizona Health Sciences are closer to developing a safe and effective non-opioid pain reliever after a study showed that...
Source: The University of Arizona: Health - November 15, 2021 Category: Universities & Medical Training Authors: mittank Source Type: research

Real-world impact of disease on functioning and activity: what is missed when using general instruments to estimate quality-adjusted life year
CONCLUSION: Differences in rankings of disease severity by metric indicate that the results of cost-utility analyses might be biased against treatments for certain diseases. As patient preferences for clinical outcomes vary, the full burden of disease should be considered in evaluations. Restricting access to treatments based on an incomplete estimate of burden could lead to misallocation of resources and a withholding of therapies that patients find valuable.PMID:34775901 | DOI:10.1080/03007995.2021.2006535
Source: Current Medical Research and Opinion - November 15, 2021 Category: Research Authors: Tingjian Yan Jesse D Ortendahl Eunice Chang Zac Wessler Amanda L Harmon Michael S Broder Source Type: research

Comorbid diseases and conditions in people with HIV in the UK
CONCLUSIONS: PLHIV in the UK were at a higher risk of developing a number of comorbid conditions, highlighting the need for regular attendance of health reviews such as the annual health reviews recommended by the British HIV Associations (BHIVA) quality standard for care, which are currently not uniformly conducted.PMID:34761727 | DOI:10.1080/03007995.2021.2003671
Source: Current Medical Research and Opinion - November 11, 2021 Category: Research Authors: Bethan I Jones Andrew Freedman Melissa J Thomas Celia Villalba-Mendez Leena Sathia Deborah Flanagan Scott Francis Craig J Currie Source Type: research

Tai Chi for anxiety and depression symptoms in cancer, stroke, heart failure, and chronic obstructive pulmonary disease: A systematic review and meta-analysis
CONCLUSION: Tai Chi has a positive effect on anxiety and depression, especially for patients with cancer, stroke, and HF. However, given the weak evidence, this approach is not a substitute for psychiatric treatment.PMID:34749040 | DOI:10.1016/j.ctcp.2021.101510
Source: Complementary Therapies in Clinical Practice - November 8, 2021 Category: Complementary Medicine Authors: Qian Cai Shu-Bin Cai Jian-Kun Chen Xiao-Hui Bai Chun-Xiang Jing Xi Zhang Ji-Qiang Li Source Type: research