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Therapy: Antibiotic Therapy
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Total 6680 results found since Jan 2013.
Multifunctional Polymer Vesicles for Synergistic Antibiotic-Antioxidant Treatment of Bacterial Keratitis
Biomacromolecules. 2023 Sep 21. doi: 10.1021/acs.biomac.3c00754. Online ahead of print.ABSTRACTAs an acute ophthalmic infection, bacterial keratitis (BK) can lead to severe visual morbidity, such as corneal perforation, intraocular infection, and permanent corneal opacity, if rapid and effective treatments are not available. In addition to eradicating pathogenic bacteria, protecting corneal tissue from oxidative damage and promoting wound healing by relieving inflammation are equally critical for the efficient treatment of BK. Besides, it is very necessary to improve the bioavailability of drugs by enhancing the ocular sur...
Source: Biomacromolecules - September 21, 2023 Category: Biochemistry Authors: Qiumeng Chen Xiaopeng Han Lu Liu Yong Duan Yifei Chen Linqi Shi Quankui Lin Liangliang Shen Source Type: research
Assessing the Utility of Multiplexed Polymerase Chain Reaction in Detecting Microorganisms Causing Infections in Critically ill Patients
This study investigated whether using multiplexed PCR for detecting microorganisms in critical septic patients affects initial antibiotic treatment and compared it to microbiological culture. It also explored scenarios where PCR is more effective in clinical practice. One hundred nineteen specimens (83 blood and 36 respiratory specimens) belonging to 93 patients were analyzed. Multiplexed PCR determinations were performed using the FA-BCID Panel (bioMérieux) for blood samples and the FA-Pneumo for respiratory samples. The mean turnaround times were 1.7 h for the FA-BCID and 1.5h for the FA-Pneumo. Conversely, they were 96...
Source: Current Microbiology - September 21, 2023 Category: Microbiology Authors: Pedro Garrido Xavier Gabald ó-Barrios Isabel Pujol-Bajador Luis Fern ández Frederic Ballester Raquel Garrido Pitter Cueto Jordi Camps Immaculada Vallverd ú Source Type: research
Cypate-loaded hollow mesoporous Prussian blue nanoparticle/hydrogel system for efficient photodynamic therapy/photothermal therapy dual-modal antibacterial therapy
This study provides ideas for the design of an antibiotic-free antimicrobial strategy against infectious diseases.PMID:37728144 | DOI:10.1002/jbm.a.37613
Source: Biomed Res - September 20, 2023 Category: Research Authors: Zheng Xing Bingyu Dong Xiaoxiao Zhang Lin Qiu Pengju Jiang Yang Xuan Xinye Ni Hongbin Xu Jianhao Wang Source Type: research
Larval therapy vs conventional silver dressings for full-thickness burns: a randomized controlled trial
CONCLUSIONS: Our findings revealed that MDT has a favorable superiority over conventional regimen for the treatment of grade-III burns, and thus further clinical trials with larger sample size are warranted to confirm these results.PMID:37726738 | DOI:10.1186/s12916-023-03063-7
Source: Cancer Control - September 19, 2023 Category: Cancer & Oncology Authors: Jasem Gaffari Kamran Akbarzadeh Mozhgan Baniardalani Reza Hosseini Safdar Masoumi Zahra Sadat Amiri Razieh Shabani Kordshouli Javad Rafinejad Mostafa Dahmardehei Source Type: research
Genomic Characterization of Salmonella enterica Resistant to Cephalosporin, Quinolones, And Macrolides
This study focused on determining the antimicrobial resistance of 373 Salmonella isolates, collected from various foods, humans, and animals, as well as the environmental sludge between 2005 and 2020 in Türkiye. Phenotypic analysis of the resistance was determined by disk diffusion method. Isolates resistant to any of the following: ciprofloxacin, pefloxacin, azithromycin, and ceftriaxone were tested for the presence of quinolone, beta-lactamase, and/or macrolide resistance genes by PCR and gel electrophoresis. Five multi-drug-resistant isolates were then further whole genome sequenced and analyzed. More than 32% (n = 120...
Source: Current Microbiology - September 19, 2023 Category: Microbiology Authors: Diala Konyali Mustafa Guzel Ye şim Soyer Source Type: research
Causative Microorganisms Isolated from Patients with Intra-Abdominal Infections and Their Drug Resistance Profiles: An 11-Year (2011-2021) Single-Center Retrospective Study
CONCLUSION: The distribution and antimicrobial susceptibility of the causative microorganisms from patients with IAIs were altered between 2011 and 2021. This finding is valuable for the implementation of evidence-based antimicrobial therapy and provides guidance for the control of hospital infections.PMID:37711085 | DOI:10.3967/bes2023.072
Source: Biomedical and Environmental Sciences : BES - September 15, 2023 Category: Biomedical Science Authors: Rui Ding Rui Rui Ma Ya Li Liu Ying Zhao Li Na Guo Hong Tao Dou Hong Li Sun Wen Jing Liu Li Zhang Yao Wang Ding Ding Li Qiao Lian Yi Ying Chun Xu Source Type: research
Role of non- < em > Helicobacter pylori < /em > gastric Helicobacters in < em > helicobacter pylori < /em > -negative gastric mucosa-associated lymphoid tissue lymphoma
World J Gastroenterol. 2023 Aug 28;29(32):4851-4859. doi: 10.3748/wjg.v29.i32.4851.ABSTRACTMarginal zone lymphomas rank as the third most prevalent form of non-Hodgkin B-cell lymphoma, trailing behind diffuse large B-cell lymphoma and follicular lymphoma. Gastric mucosa-associated lymphoid tissue lymphoma (GML) is a low-grade B-cell neoplasia frequently correlated with Helicobacter pylori (H. pylori)-induced chronic gastritis. On the other hand, a specific subset of individuals diagnosed with GML does not exhibit H. pylori infection. In contrast to its H. pylori-positive counterpart, it was previously believed that H. pylo...
Source: World Journal of Gastroenterology : WJG - September 13, 2023 Category: Gastroenterology Authors: Fabian Fellipe Bueno Lemos Marcel Silva Luz Samuel Luca Rocha Pinheiro K ádima Nayara Teixeira Fabr ício Freire de Melo Source Type: research
