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Cancer: Prostate Cancer

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Total 25934 results found since Jan 2013.

MicroRNAs Regulate Tumorigenesis by Downregulating SOCS3 Expression: An < em > In silico < /em > Approach
This study identifies the interactions of known (miR-203a-5p) and novel (miR-6756-5p, miR-6732-5p, miR-1203, miR-6887-5p) microRNAs with SOCS3 regions due to their maximum interactions. Identifying the interactions of these microRNAs with SOCS3 will significantly advance the understanding of oncomiRs (miRNAs that are associated with cancer development) in tumor development due to their influence on SOCS3 expression. These insights will assist in future studies to understand the significance of miRNA-SOCS3-associated tumor development and progression.PMID:37701630 | PMC:PMC10493049 | DOI:10.1177/11779322231193535
Source: Bioinformatics and Biology Insights - September 13, 2023 Category: Bioinformatics Authors: Sura Al-Asadi Hiba Mansour Ahmed Jwaid Ataimish Rusul Al-Kahachi Jamila Rampurawala Source Type: research

Opportunities for prostate-specific membrane antigen hybrid imaging in prostate cancer
Urologie. 2023 Sep 13. doi: 10.1007/s00120-023-02189-z. Online ahead of print.ABSTRACTProstate-specific membrane antigen (PSMA) hybrid imaging is a promising new technique gaining importance in the field of prostate cancer (PCa) diagnosis and treatment planning. By combining PSMA radioligands and computed tomography (CT) or magnetic resonance imaging (MRI), PSMA hybrid imaging opens up new diagnostic opportunities. PSMA-PET/CT (PET: positron-emission tomography) is already well established in high-risk PCa for primary staging and tumor localization when biochemical recurrence occurs. Further potential indications for PSMA-...
Source: Nuklearmedizin - September 13, 2023 Category: Radiology Authors: Anna-Sophie Strau ß Christian Bolenz Ambros J Beer Friedemann Zengerling Meinrad Beer Jonathan Miksch Source Type: research

Racial differences in serum chemokines in prostate cancer patients
CONCLUSION: Lower levels of CCL23 in AA prostate cancer patient sera and tumor tissues and high CXCL2 and CXCL5 may contribute to aggressive prostate cancer, as often seen in AA men. The disproportionate levels of serum chemokines associated with race warrant further exploration to improve equitability in precision oncology to benefit prostate cancer patients.PMID:37698493 | DOI:10.1002/cncr.35012
Source: Cancer Control - September 12, 2023 Category: Cancer & Oncology Authors: Dev Karan Jo Wick Seema Dubey Chandan Kumar-Sinha Javed Siddiqui Lakshmi P Kunju Kenneth A Iczkowski Arul M Chinnaiyan Source Type: research

Comorbidity in patients with Lichen sclerosus: a retrospective cohort study
This study confirmed the association between LS and vulvar cancer (OR = 17.4; 95% CI 12.1-25.3), penis cancer (OR = 9.1; 95% CI 4.3-18.9), prostate cancer (OR = 2.0; 95% CI 1.6-2.4) and breast cancer (OR = 1.6; 95% CI 1.4-1.8). LS was also associated with Crohn´s disease (OR = 2.0; 95% CI 1.6-2.6) and diabetes mellitus type 1 (OR = 1.9; 95% CI 1.6-2.1). The present study revealed novel important data regarding the association of LS with cancer and autoimmune diseases, emphasising the importance of sufficient treatment and follow-up of patients with LS. However, future studies are needed to confirm these results and the po...
Source: Cell Research - September 12, 2023 Category: Cytology Authors: Sandra Jerkovic Gulin Filippa Lundin Oliver Seifert Source Type: research

Evaluation of the Potential Therapeutic Properties of Liquidambar orientalis Oil
In conclusion, the oil from the Sigla tree offers promising therapeutic potential and warrants further exploration.PMID:37699128 | DOI:10.1002/cbdv.202300291
Source: Chemistry and Biodiversity - September 12, 2023 Category: Biochemistry Authors: Mehmet Cengiz Baloglu Lutfiye Yildiz Ozer Buket Pirci Gokhan Zengin Abdullahi Ibrahim Uba Yasemin Celik Altunoglu Source Type: research

Comprehensive Review on Recent Strategies for Management of Prostate Cancer: Therapeutic Targets and SAR
This article also emphasized the recent advances in the field of medicinal chemistry of prostate cancer agents.PMID:37694781 | DOI:10.2174/1389557523666230911141339
Source: Mini Reviews in Medicinal Chemistry - September 11, 2023 Category: Chemistry Authors: Manish Chaudhary Shubham Kumar Paranjeet Kaur Sanjeev Kumar Sahu Amit Mittal Source Type: research

Prostate health index can stratify patients with Prostate Imaging Reporting and Data System score 3 lesions on magnetic resonance imaging to reduce prostate biopsies
Asian J Androl. 2023 Aug 22. doi: 10.4103/aja202332. Online ahead of print.ABSTRACTWe aim to evaluate prostate health index as an additional risk-stratification tool in patients with Prostate Imaging Reporting and Data System score 3 lesions on multiparametric magnetic resonance imaging. Men with biochemical or clinical suspicion of having prostate cancer who underwent multiparametric magnetic resonance imaging in two tertiary centers (Queen Mary Hospital and Princess Margaret Hospital, Hong Kong, China) between January 2017 and June 2022 were included. Ultrasound-magnetic resonance imaging fusion biopsies were performed a...
Source: Asian Journal of Andrology - September 11, 2023 Category: Urology & Nephrology Authors: John Shung-Lai Leung Wai-Kit Ma Brian Sze-Ho Ho Stacia Tsun-Tsun Chun Rong Na Yongle Zhan Chi-Yuen Ng Chi-Ho Ip Ada Tsui-Lin Ng Yiu-Chung Lam Source Type: research

High-Intensity Focused Ultrasound (Sonablate < sup > ® < /sup > ) for Prostate Cancer: Preliminary Outcomes in Taiwan
CONCLUSIONS: The results of Sonablate® HIFU in Taiwan indicated adequate short-term cancer control, excellent potency, and continence preservation. HIFU can achieve improvement of IPSS with low complication rates.PMID:37697133 | DOI:10.1245/s10434-023-14250-4
Source: Ann Oncol - September 11, 2023 Category: Cancer & Oncology Authors: Mu Yao Tsai Chih Tai Lin Ping Hsuan Chiang Po Hui Chiang Ping Chia Chiang Source Type: research

Growing Deficit in New Cancer Diagnoses 2 Years Into the COVID-19 Pandemic: A National Multicenter Study
CONCLUSION: Disruptions in new diagnoses of four common cancers (prostate, lung, bladder, and colorectal) seen early in the COVID-19 pandemic have persisted for 2 years. Although reductions improved from the early pandemic, new reductions during the Delta and Omicron waves demonstrate the continued impact of the COVID-19 pandemic on cancer care.PMID:37695458 | DOI:10.1245/s10434-023-14217-5
Source: Ann Oncol - September 11, 2023 Category: Cancer & Oncology Authors: Brian R Englum Shalini Sahoo Minerva Mayorga-Carlin Hilary Hayssen Tariq Siddiqui Douglas J Turner John D Sorkin Brajesh K Lal Source Type: research

Global efficacy and clinical application of androgen receptor inhibitors in metastatic prostate cancer
Chin Clin Oncol. 2023 Sep 6:cco-23-59. doi: 10.21037/cco-23-59. Online ahead of print.NO ABSTRACTPMID:37691348 | DOI:10.21037/cco-23-59
Source: Ann Oncol - September 11, 2023 Category: Cancer & Oncology Authors: Ulka Vaishampayan Source Type: research

LMNTD2-AS1 regulates immune cell infiltration and promotes prostate cancer progression by targeting FUS to regulate NRF2 signal pathway
This study aimed to identify lncRNAs associated with overall survival (OS) and progression-free interval (PFI) in prostate cancer (PCa) patients and to elucidate the driving mechanisms and functions of these lncRNAs. We utilized the TCGA database to screen for lncRNAs linked with OS and PFI. KM survival analysis, ROC curve analysis, and Cox survival analysis were employed to assess the prognostic significance of lncRNAs in PCa patients. We conducted a loss-of-function assay to explore the role of lncRNAs in PCa. Correlation analysis was performed to study the relationship between lncRNAs and immune cell infiltration. Lasso...
Source: Cell Research - September 11, 2023 Category: Cytology Authors: Haoming Wu Ning Liu Aifeng He Haiyang Li Hui Liu Jinke Qian Weipu Mao Guangbo Fu Source Type: research