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Total 1545 results found since Jan 2013.
The Neurokinin-1 Receptor Is Essential for the Viability of Human Glioma Cells: A Possible Target for Treating Glioblastoma
CONCLUSIONS: Our results show for the first time that the expression of the TAC1R gene (NK-1R) is essential for the viability of GAMG and U-87 MG glioma cells. On the contrary, the TAC1R gene is not essential for the viability of normal cells, confirming that NK-1R could be a promising and specific therapeutic target for the treatment of glioma.PMID:35434136 | PMC:PMC9006081 | DOI:10.1155/2022/6291504
Source: Biomed Res - April 18, 2022 Category: Research Authors: Mario F Mu ñoz Sandro Arg üelles Marisa Rosso Rafael Medina Rafael Cove ñas Antonio Ayala Miguel Mu ñoz Source Type: research
Inhibition of Ubiquitin-specific Protease 4 Attenuates Epithelial —Mesenchymal Transition of Renal Tubular Epithelial Cells via Transforming Growth Factor Beta Receptor Type I
ConclusionUSP4 promotes the EMT of RTECs through upregulating T βRI, thereby facilitating renal interstitial fibrosis. These findings may provide a potential target of USP4 in the treatment of renal fibrosis.
Source: Journal of Huazhong University of Science and Technology -- Medical Sciences -- - September 30, 2022 Category: Research Source Type: research
FOXM1 Contributes to Chemotherapy Sensitivity in Cervical Cancer by Regulating TTK
CONCLUSIONS: FOXM1 regulated TTK and affected the therapeutic efficacy of cisplatin and paclitaxel in cervical cancer.PMID:37272088 | DOI:10.24976/Discov.Med.202335176.22
Source: Discovery Medicine - June 5, 2023 Category: Research Authors: Qing Tang Anli Xu Ying Yang Yunmei Zhang Jianan Sun Source Type: research
