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Total 281 results found since Jan 2013.
miR-145 Alleviates Smooth Muscle Cell Phenotype Transition via ADAM17-Mediated ACE2 Shedding
In conclusion, miR-145 alleviates phenotype transition from contractile to synthetic type via ADAM17-mediated ACE2 shedding in VSMCs and retains the activation of ACE2-Ang-(1-7)-Mas axis, which may benefit the vascular structural remodeling in the metabolic hypertension.PMID:37521117 | PMC:PMC10374374 | DOI:10.1155/2023/9497716
Source: International Journal of Hypertension - July 31, 2023 Category: Cardiology Authors: Juan Wen Baiyi Tang Lan Guo Wei Chen Xiaohong Tang Source Type: research
Evaluation of an Integrin α < sub > v < /sub > β < sub > 3 < /sub > Radiotracer, < sup > 18 < /sup > FF-FPP-RGD < sub > 2 < /sub > , for Monitoring Pharmacological Effects of Integrin α < sub > v < /sub > siRNA in the NASH Liver
CONCLUSION: This study suggests that [18F]F-FPP-RGD2 PET imaging is a promising radiotracer for monitoring hepatic integrin αv protein levels and hepatic function in NASH pathology.PMID:37483876 | PMC:PMC10359219 | DOI:10.1007/s13139-023-00791-9
Source: Molecular Medicine - July 24, 2023 Category: Molecular Biology Authors: Shuichi Hiroyama Keiko Matsunaga Miwa Ito Hitoshi Iimori Ippei Morita Jun Nakamura Eku Shimosegawa Kohji Abe Source Type: research
Hydroxysafflor yellow A inhibits endothelial cell ferroptosis in diabetic atherosclerosis mice by regulating miR-429/SLC7A11
CONCLUSIONS: HSYA is expected to become an important health drug to prevent the occurrence and development of T2DM/AS.PMID:37410531 | DOI:10.1080/13880209.2023.2225543
Source: Atherosclerosis - July 6, 2023 Category: Cardiology Authors: Jianjie Rong Chuanyong Li Qiang Zhang Guangfeng Zheng Weijian Fan Zhichang Pan Shuming Shi Source Type: research
