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Source: Cell Biology International
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Total 159 results found since Jan 2013.
Analysis of the expression and association of retinoblastoma binding protein 6 (RBBP6) with the JNK signaling pathway in prostate cancers.
This study aims to investigate the expression of retinoblastoma binding protein 6 (RBBP6) in prostate cancer (PCa) and its association with the c-Jun N-terminal kinase (JNK) pathway. Immunohistochemistry was used to detect RBBP6 and JNK1/2 expression in PCa and benign prostatic hyperplasia (BPH) tissues. RBBP6 expression in PCa cells (LNCap, PC3 and DU145) and noncancerous prostate epithelial cells (RWPE-1) was determined by qRT-PCR and Western blotting. PC3 and DU145 cells were transfected with RBBP6 siRNAs to examine the biological characteristics. Anisomycin (a JNK activator) with/without RBBP6 siRNA was used to treat P...
Source: Cell Biology International - July 13, 2020 Category: Cytology Authors: Guan WY, Zhao S, Luo YN Tags: Cell Biol Int Source Type: research
NLRC3 silencing accelerates the invasion of hepatocellular carcinoma cell via IL-6 induced JAK2/STAT3 pathway activation.
This article is protected by copyright. All rights reserved.
PMID: 32584509 [PubMed - as supplied by publisher]
Source: Cell Biology International - June 24, 2020 Category: Cytology Authors: Kang JH, Li MJ, Luan PP, Jiang DK, Chen YW, Xu X, Yu Q, Xu YW, Su Q, Peng WH, Jian WX Tags: Cell Biol Int Source Type: research
The TMEM98 mRNA promotes proliferation and invasion of gastric cells by directly interacting with the NF90 protein.
In conclusion, TMEM98 mRNA enhanced the proliferation and invasion of GC cells by interacting with the NF90 protein. This article is protected by copyright. All rights reserved.
PMID: 32379372 [PubMed - as supplied by publisher]
Source: Cell Biology International - May 6, 2020 Category: Cytology Authors: Ao X, Li X, Chen Y, Zang Z, Guo W, Liang J Tags: Cell Biol Int Source Type: research
FCRL3 promotes IL-10 expression in B cells through the SHP-1 and p38 MAPK signalling pathways.
This study further found that FCRL3 and IL-10 expression was downregulated in MS patients, but the expression of these proteins was higher in the remission phase than that in the acute phase. The C allele of rs7528684 was associated with MS, and the CC genotype could lead to the upregulation of FCRL3 expression and the increase in IL-10 secretion. Further in vitro experiments with B cells found that LPS promoted FCRL3 expression in a dose- and time-dependent manner, thereby promoting IL-10 secretion. LPS regulated SHP-1 expression and p38 MAPK pathway activation through FCRL3, and FCRL3 upregulated the SHP-1 expression and...
Source: Cell Biology International - May 5, 2020 Category: Cytology Authors: Cui X, Liu CM, Liu QB Tags: Cell Biol Int Source Type: research
MicroRNA-93-5p expression in tumor tissue and its tumor suppressor function via targeting programmed death ligand-1 in colorectal cancer.
This article is protected by copyright. All rights reserved.
PMID: 32068322 [PubMed - as supplied by publisher]
Source: Cell Biology International - February 17, 2020 Category: Cytology Authors: Chen YL, Wang GX, Lin BA, Huang JS Tags: Cell Biol Int Source Type: research
Extracellular vesicle-derived circ_SLC19A1 promotes prostate cancer cell growth and invasion through the miR-497/septin 2 pathway.
This article is protected by copyright. All rights reserved.
PMID: 31903637 [PubMed - as supplied by publisher]
Source: Cell Biology International - January 4, 2020 Category: Cytology Authors: Zheng Y, Li JX, Chen CJ, Lin ZY, Liu JX, Lin FJ Tags: Cell Biol Int Source Type: research
Phosphorylation of Dab2 is involved in inhibited VEGF-VEGFR-2 signaling induced by downregulation of Syndecan-1 in glomerular endothelial cell.
In conclusion, we speculated that, phosphorylation of Dab2 is involved in preventing activation of VEGF-VEGFR-2 signaling in GEnC transfected with Syndecan-1 siRNA. This provide a new target for the therapy of GEnC injury and kidney disease. This article is protected by copyright. All rights reserved.
PMID: 31868265 [PubMed - as supplied by publisher]
Source: Cell Biology International - December 22, 2019 Category: Cytology Authors: Jing Z, Jia-Jun W, Wei-Jie Y Tags: Cell Biol Int Source Type: research
Involvement of Yes-associated protein 1 (YAP1) in doxorubicin-induced cytotoxicity in H9c2 cardiac cells.
In conclusion, these results suggest that doxorubicin-induced cardiac cell death is mediated in part by down-regulation of YAP1 and YAP1-targeted gene, Akt. Modulating YAP1 and its related Hippo pathway on local cardiomyocytes may be a promising therapeutic approach for doxorubicin-induced cardiotoxicity. This article is protected by copyright. All rights reserved.
PMID: 31833156 [PubMed - as supplied by publisher]
Source: Cell Biology International - December 12, 2019 Category: Cytology Authors: Takaguri A, Akihiro O, Sasano J, Satoh K Tags: Cell Biol Int Source Type: research
Melatonin reverses the oxidative stress and mitochondrial dysfunction caused by LETM1 silencing.
This article is protected by copyright. All rights reserved.
PMID: 31777134 [PubMed - as supplied by publisher]
Source: Cell Biology International - November 26, 2019 Category: Cytology Authors: Aral C, Demirkesen S, Bircan R, Yasar Sirin D Tags: Cell Biol Int Source Type: research
Subcellular dynamics of variants of SG2NA in NIH3T3 fibroblasts.
This article is protected by copyright. All rights reserved.
PMID: 31773824 [PubMed - as supplied by publisher]
Source: Cell Biology International - November 25, 2019 Category: Cytology Authors: Chauhan P, Gupta R, Prakash Jain B, Pandey S, Goswami SK Tags: Cell Biol Int Source Type: research
Derlin-1 exhibits oncogenic activities and indicates unfavorable prognosis in breast cancer.
This article is protected by copyright. All rights reserved.
PMID: 31670413 [PubMed - as supplied by publisher]
Source: Cell Biology International - October 30, 2019 Category: Cytology Authors: Zeng J, Tian Q, Zeng Z, Cai J, Ye M, Liu Y, Liu A Tags: Cell Biol Int Source Type: research
PTEN promotes intervertebral disc degeneration by regulating nuclear pulposus cell behaviors.
This article is protected by copyright. All rights reserved.
PMID: 31663655 [PubMed - as supplied by publisher]
Source: Cell Biology International - October 29, 2019 Category: Cytology Authors: Xi Y, Ma J, Chen Y Tags: Cell Biol Int Source Type: research
Transcription factor E2F4 is a positive regulator of milk biosynthesis and proliferation of bovine mammary epithelial cells.
This article is protected by copyright. All rights reserved.
PMID: 31475773 [PubMed - as supplied by publisher]
Source: Cell Biology International - September 1, 2019 Category: Cytology Authors: Zhen Z, Zhang M, Yuan X, Li M Tags: Cell Biol Int Source Type: research
Role of km23-1 in Ras/ERK regulationkm23-1/DYNLRB1 regulation of MEK/ERK signaling and R-Ras in invasive human colorectal cancer cells.
This article is protected by copyright. All rights reserved.
PMID: 31393067 [PubMed - as supplied by publisher]
Source: Cell Biology International - August 7, 2019 Category: Cytology Authors: Raza A, Pandey MS, Jin Q, Mulder KM Tags: Cell Biol Int Source Type: research
Tripartite motif protein 52 (TRIM52) promoted fibrosis in LX-2 cells through PPM1A-mediated Smad2/3 pathway.
This article is protected by copyright. All rights reserved.
PMID: 31329338 [PubMed - as supplied by publisher]
Source: Cell Biology International - July 21, 2019 Category: Cytology Authors: Zhou J, Lan Q, Li W, Yang L, You J, Zhang YM, Ni W Tags: Cell Biol Int Source Type: research
