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Source: Cell Biology International
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Total 159 results found since Jan 2013.
Calycosin suppresses colorectal cancer progression by targeting ER β, upregulating PTEN, and inhibiting PI3K/Akt signal pathway
In this study, we analyzed the effect of calycosin on the viability and apoptosis of human CRC HCT116 and SW480 cells via MTT assay, flow cytometry assay, and caspase-3/7 activity assay. The protein expressions of estrogen receptor β (ERβ), PTEN, and PI3K/Akt signal pathways were determined by Western blot analysis. And then, the alterations of biological behavior in CRC cells transfected with ERβ siRNA were analyzed. Mouse xenograft models were further performed to detect the antitumor effect in vivo. The results show that calycosin reduces CRC cell viability, induces cell apoptosis, and suppresses xenograft tumor grow...
Source: Cell Biology International - July 17, 2022 Category: Cytology Authors: Lin Zhu Sha Liu Yi-Fan Liao Yan-Mei Sheng Ji-Chun He Zheng-Xue Cai Qiong Man Yi-Ying Wu Source Type: research
ANKHD1 contributes to the malignant phenotype of triple-negative breast cancer cells
Cell Biol Int. 2022 Jul 16. doi: 10.1002/cbin.11844. Online ahead of print.ABSTRACTAnkyrin repeat and KH domain-containing protein 1, ANKHD1, has been identified as a regulator of signaling pathways and cellular processes of relevance in carcinogenesis. However, the role of ANKHD1 in breast cancer remains unclear. The aim of the present study was to characterize the expression pattern and involvement of ANKHD1 in the malignant phenotype of breast cancer cell lines and to investigate the clinical relevance of ANKHD1 in a breast cancer context. Gene and protein expressions were assessed in the cell lines by quantitative reve...
Source: Cell Biology International - July 17, 2022 Category: Cytology Authors: Bruna O de Almeida Larissa C de Almeida Leticia V Costa-Lotufo Jo ão A Machado-Neto Source Type: research
Calycosin suppresses colorectal cancer progression by targeting ER β, upregulating PTEN, and inhibiting PI3K/Akt signal pathway
In this study, we analyzed the effect of calycosin on the viability and apoptosis of human CRC HCT116 and SW480 cells via MTT assay, flow cytometry assay, and caspase-3/7 activity assay. The protein expressions of estrogen receptor β (ERβ), PTEN, and PI3K/Akt signal pathways were determined by Western blot analysis. And then, the alterations of biological behavior in CRC cells transfected with ERβ siRNA were analyzed. Mouse xenograft models were further performed to detect the antitumor effect in vivo. The results show that calycosin reduces CRC cell viability, induces cell apoptosis, and suppresses xenograft tumor grow...
Source: Cell Biology International - July 17, 2022 Category: Cytology Authors: Lin Zhu Sha Liu Yi-Fan Liao Yan-Mei Sheng Ji-Chun He Zheng-Xue Cai Qiong Man Yi-Ying Wu Source Type: research
ANKHD1 contributes to the malignant phenotype of triple-negative breast cancer cells
Cell Biol Int. 2022 Jul 16. doi: 10.1002/cbin.11844. Online ahead of print.ABSTRACTAnkyrin repeat and KH domain-containing protein 1, ANKHD1, has been identified as a regulator of signaling pathways and cellular processes of relevance in carcinogenesis. However, the role of ANKHD1 in breast cancer remains unclear. The aim of the present study was to characterize the expression pattern and involvement of ANKHD1 in the malignant phenotype of breast cancer cell lines and to investigate the clinical relevance of ANKHD1 in a breast cancer context. Gene and protein expressions were assessed in the cell lines by quantitative reve...
Source: Cell Biology International - July 17, 2022 Category: Cytology Authors: Bruna O de Almeida Larissa C de Almeida Leticia V Costa-Lotufo Jo ão A Machado-Neto Source Type: research
Calycosin suppresses colorectal cancer progression by targeting ER β, upregulating PTEN, and inhibiting PI3K/Akt signal pathway
In this study, we analyzed the effect of calycosin on the viability and apoptosis of human CRC HCT116 and SW480 cells via MTT assay, flow cytometry assay, and caspase-3/7 activity assay. The protein expressions of estrogen receptor β (ERβ), PTEN, and PI3K/Akt signal pathways were determined by Western blot analysis. And then, the alterations of biological behavior in CRC cells transfected with ERβ siRNA were analyzed. Mouse xenograft models were further performed to detect the antitumor effect in vivo. The results show that calycosin reduces CRC cell viability, induces cell apoptosis, and suppresses xenograft tumor grow...
Source: Cell Biology International - July 17, 2022 Category: Cytology Authors: Lin Zhu Sha Liu Yi-Fan Liao Yan-Mei Sheng Ji-Chun He Zheng-Xue Cai Qiong Man Yi-Ying Wu Source Type: research
ANKHD1 contributes to the malignant phenotype of triple-negative breast cancer cells
Cell Biol Int. 2022 Jul 16. doi: 10.1002/cbin.11844. Online ahead of print.ABSTRACTAnkyrin repeat and KH domain-containing protein 1, ANKHD1, has been identified as a regulator of signaling pathways and cellular processes of relevance in carcinogenesis. However, the role of ANKHD1 in breast cancer remains unclear. The aim of the present study was to characterize the expression pattern and involvement of ANKHD1 in the malignant phenotype of breast cancer cell lines and to investigate the clinical relevance of ANKHD1 in a breast cancer context. Gene and protein expressions were assessed in the cell lines by quantitative reve...
Source: Cell Biology International - July 17, 2022 Category: Cytology Authors: Bruna O de Almeida Larissa C de Almeida Leticia V Costa-Lotufo Jo ão A Machado-Neto Source Type: research
Calycosin suppresses colorectal cancer progression by targeting ER β, upregulating PTEN, and inhibiting PI3K/Akt signal pathway
In this study, we analyzed the effect of calycosin on the viability and apoptosis of human CRC HCT116 and SW480 cells via MTT assay, flow cytometry assay, and caspase-3/7 activity assay. The protein expressions of estrogen receptor β (ERβ), PTEN, and PI3K/Akt signal pathways were determined by Western blot analysis. And then, the alterations of biological behavior in CRC cells transfected with ERβ siRNA were analyzed. Mouse xenograft models were further performed to detect the antitumor effect in vivo. The results show that calycosin reduces CRC cell viability, induces cell apoptosis, and suppresses xenograft tumor grow...
Source: Cell Biology International - July 17, 2022 Category: Cytology Authors: Lin Zhu Sha Liu Yi-Fan Liao Yan-Mei Sheng Ji-Chun He Zheng-Xue Cai Qiong Man Yi-Ying Wu Source Type: research
ANKHD1 contributes to the malignant phenotype of triple-negative breast cancer cells
Cell Biol Int. 2022 Jul 16. doi: 10.1002/cbin.11844. Online ahead of print.ABSTRACTAnkyrin repeat and KH domain-containing protein 1, ANKHD1, has been identified as a regulator of signaling pathways and cellular processes of relevance in carcinogenesis. However, the role of ANKHD1 in breast cancer remains unclear. The aim of the present study was to characterize the expression pattern and involvement of ANKHD1 in the malignant phenotype of breast cancer cell lines and to investigate the clinical relevance of ANKHD1 in a breast cancer context. Gene and protein expressions were assessed in the cell lines by quantitative reve...
Source: Cell Biology International - July 17, 2022 Category: Cytology Authors: Bruna O de Almeida Larissa C de Almeida Leticia V Costa-Lotufo Jo ão A Machado-Neto Source Type: research
Calycosin suppresses colorectal cancer progression by targeting ER β, upregulating PTEN, and inhibiting PI3K/Akt signal pathway
In this study, we analyzed the effect of calycosin on the viability and apoptosis of human CRC HCT116 and SW480 cells via MTT assay, flow cytometry assay, and caspase-3/7 activity assay. The protein expressions of estrogen receptor β (ERβ), PTEN, and PI3K/Akt signal pathways were determined by Western blot analysis. And then, the alterations of biological behavior in CRC cells transfected with ERβ siRNA were analyzed. Mouse xenograft models were further performed to detect the antitumor effect in vivo. The results show that calycosin reduces CRC cell viability, induces cell apoptosis, and suppresses xenograft tumor grow...
Source: Cell Biology International - July 17, 2022 Category: Cytology Authors: Lin Zhu Sha Liu Yi-Fan Liao Yan-Mei Sheng Ji-Chun He Zheng-Xue Cai Qiong Man Yi-Ying Wu Source Type: research
ANKHD1 contributes to the malignant phenotype of triple-negative breast cancer cells
Cell Biol Int. 2022 Jul 16. doi: 10.1002/cbin.11844. Online ahead of print.ABSTRACTAnkyrin repeat and KH domain-containing protein 1, ANKHD1, has been identified as a regulator of signaling pathways and cellular processes of relevance in carcinogenesis. However, the role of ANKHD1 in breast cancer remains unclear. The aim of the present study was to characterize the expression pattern and involvement of ANKHD1 in the malignant phenotype of breast cancer cell lines and to investigate the clinical relevance of ANKHD1 in a breast cancer context. Gene and protein expressions were assessed in the cell lines by quantitative reve...
Source: Cell Biology International - July 17, 2022 Category: Cytology Authors: Bruna O de Almeida Larissa C de Almeida Leticia V Costa-Lotufo Jo ão A Machado-Neto Source Type: research
Calycosin suppresses colorectal cancer progression by targeting ER β, upregulating PTEN, and inhibiting PI3K/Akt signal pathway
In this study, we analyzed the effect of calycosin on the viability and apoptosis of human CRC HCT116 and SW480 cells via MTT assay, flow cytometry assay, and caspase-3/7 activity assay. The protein expressions of estrogen receptor β (ERβ), PTEN, and PI3K/Akt signal pathways were determined by Western blot analysis. And then, the alterations of biological behavior in CRC cells transfected with ERβ siRNA were analyzed. Mouse xenograft models were further performed to detect the antitumor effect in vivo. The results show that calycosin reduces CRC cell viability, induces cell apoptosis, and suppresses xenograft tumor grow...
Source: Cell Biology International - July 17, 2022 Category: Cytology Authors: Lin Zhu Sha Liu Yi-Fan Liao Yan-Mei Sheng Ji-Chun He Zheng-Xue Cai Qiong Man Yi-Ying Wu Source Type: research
ANKHD1 contributes to the malignant phenotype of triple-negative breast cancer cells
Cell Biol Int. 2022 Jul 16. doi: 10.1002/cbin.11844. Online ahead of print.ABSTRACTAnkyrin repeat and KH domain-containing protein 1, ANKHD1, has been identified as a regulator of signaling pathways and cellular processes of relevance in carcinogenesis. However, the role of ANKHD1 in breast cancer remains unclear. The aim of the present study was to characterize the expression pattern and involvement of ANKHD1 in the malignant phenotype of breast cancer cell lines and to investigate the clinical relevance of ANKHD1 in a breast cancer context. Gene and protein expressions were assessed in the cell lines by quantitative reve...
Source: Cell Biology International - July 17, 2022 Category: Cytology Authors: Bruna O de Almeida Larissa C de Almeida Leticia V Costa-Lotufo Jo ão A Machado-Neto Source Type: research
siRNA-based nanotherapeutics as emerging modalities for immune-mediated diseases: A preliminary review
This study will pave the way for new avenues of research into the diagnosis and treatment of IMDs.PMID:35830711 | DOI:10.1002/cbin.11841
Source: Cell Biology International - July 13, 2022 Category: Cytology Authors: Saman Sargazi Rabia Arshad Reza Ghamari Abbas Rahdar Ali Bakhshi Sonia Fathi Karkan Narges Ajalli Muhammad Bilal Ana M D íez-Pascual Source Type: research
