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Knockdown of DEAD-box 51 inhibits tumor growth of esophageal squamous cell carcinoma < em > via < /em > the PI3K/AKT pathway
CONCLUSION: Our study suggests for the first time that DDX51 promotes cancer cell proliferation by regulating the PI3K/AKT pathway; thus, DDX51 might be a therapeutic target for ESCC.PMID:35125830 | PMC:PMC8790558 | DOI:10.3748/wjg.v28.i4.464
Source: World Journal of Gastroenterology : WJG - February 7, 2022 Category: Gastroenterology Authors: Dong-Xin Hu Qi-Feng Sun Lin Xu Hong-Da Lu Fan Zhang Zhen-Miao Li Ming-Yan Zhang Source Type: research
Downregulation of metallothionein 2A reduces migration, invasion and proliferation activities in human squamous cell carcinoma cells
CONCLUSIONS: MT2A downregulation reduced cell proliferation, migration and invasion activities. Therefore, MT2A has an important role in cell proliferation, migration and invasion in human oral SCC cells.PMID:35107738 | DOI:10.1007/s11033-022-07206-6
Source: Mol Biol Cell - February 2, 2022 Category: Molecular Biology Authors: Aline Marques Dias Ra íssa Pinheiro de Mendonça Maria Sueli da Silva Kataoka Ruy G Jaeger Jo ão de Jesus Viana Pinheiro S érgio de Melo Alves Junior Source Type: research
