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Cancer: Cervical Cancer
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Total 449 results found since Jan 2013.
LncRNA LINC00649 aggravates the progression of cervical cancer through sponging miR-216a-3p
CONCLUSIONS: The LINC00649 expression may act as a prognostic predictor and may aggravate cervical cancer progression by targeting miR-216a-3p, providing potential therapeutic targets for patients with cervical cancer.PMID:36054700 | DOI:10.1111/jog.15405
Source: Cell Research - September 2, 2022 Category: Cytology Authors: Congying Si Lanlan Yang Xu Cai Source Type: research
A lipid nanoparticle platform for mRNA delivery through repurposing of cationic amphiphilic drugs
J Control Release. 2022 Aug 10:S0168-3659(22)00514-4. doi: 10.1016/j.jconrel.2022.08.009. Online ahead of print.ABSTRACTSince the recent clinical approval of siRNA-based drugs and COVID-19 mRNA vaccines, the potential of RNA therapeutics for patient healthcare has become widely accepted. Lipid nanoparticles (LNPs) are currently the most advanced nanocarriers for RNA packaging and delivery. Nevertheless, the intracellular delivery efficiency of state-of-the-art LNPs remains relatively low and safety- and immunogenicity concerns with synthetic lipid components persist, altogether rationalizing the exploration of alternative ...
Source: Cancer Control - August 13, 2022 Category: Cancer & Oncology Authors: Bram Bogaert F élix Sauvage Roberta Guagliardo Cristina Muntean Van Phuc Nguyen Eline Pottie Mike Wels An-Katrien Minnaert Riet De Rycke Qiangbing Yang Dan Peer Niek Sanders Katrien Remaut Yannis M Paulus Christophe Stove Stefaan C De Smedt Koen Raemdonc Source Type: research
Deficiency of kin17 Facilitates Apoptosis of Cervical Cancer Cells by Modulating Caspase 3, PARP, and Bcl-2 Family Proteins
CONCLUSION: Our findings demonstrated that kin17 knockdown facilitates apoptosis of cervical cancer cells by targeting caspase 3, PARP, and Bcl-2 family proteins. Besides, kin17 could regulate cancer cell apoptosis through the mitochondrial pathway and could be used as a novel therapeutic target for the regulation of cell apoptosis in cervical cancer.PMID:35909901 | PMC:PMC9328945 | DOI:10.1155/2022/3156968
Source: Journal of Oncology - August 1, 2022 Category: Cancer & Oncology Authors: Bingsen Su Meifeng Zhong Yuzhao Zhang Kunhe Wu Qiyuan Huang Chuiyu Zhu Tao Zeng Source Type: research
MiR-218 Affects the Invasion and Metastasis of Cervical Cancer Cells by Inhibiting the Expression of SFMBT1 and DCUNIDI
Cell Mol Biol (Noisy-le-grand). 2022 Feb 28;68(2):81-86. doi: 10.14715/cmb/2022.68.2.12.ABSTRACTAs the second most common gynecological tumor in the world, cervical cancer has always been a female killer.Some studies have shown that miR-218 can inhibit the invasion and migration of cervical cancer cells through two target genes, SFMBT1and DCUNIDI. On this basis, this paper presents the study that miR-218 affects the invasion and migration of cervical cancer cells by inhibiting the expression of target genes, SFMBT1 and DCUNIDI. In this paper, we used the control experiment to study. In the fluorescence experiment, we confi...
Source: Cancer Control - July 23, 2022 Category: Cancer & Oncology Authors: Huan Li Xuzhuo An Qiaoshan Fu Source Type: research
