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Specialty: Gastroenterology
Cancer: Gastric (Stomach) Cancer
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Total 49 results found since Jan 2013.
Suppression of galectin-4 attenuates peritoneal metastasis of poorly differentiated gastric cancer cells
ConclusionsWe clarified the role of galectin-4 in the development of peritoneal dissemination of poorly differentiated gastric cancer cells. Our data highlight the diagnostic and therapeutic potential of galectin-4 in the peritoneal dissemination of gastric cancer.
Source: Gastric Cancer - January 25, 2023 Category: Gastroenterology Source Type: research
Transcriptomic profiling on localized gastric cancer identified CPLX1 as a gene promoting malignant phenotype of gastric cancer and a predictor of recurrence after surgery and subsequent chemotherapy
ConclusionsCPLX1 may represent a biomarker for recurrence of gastric cancer and a target for therapy.
Source: Journal of Gastroenterology - June 21, 2022 Category: Gastroenterology Source Type: research
Centromeric protein K (CENPK) promotes gastric cancer proliferation and migration via interacting with XRCC5
ConclusionCENPK promotes GC cell proliferation and migration via interacting with XRCC5 and may be a novel prognostic factor or therapeutic target for CENPK.
Source: Gastric Cancer - June 17, 2022 Category: Gastroenterology Source Type: research
The expression of the alpha1 subunit of Na+/K+-ATPase is related to tumor development and clinical outcomes in gastric cancer
ConclusionsATP1A1 appears to regulate tumor progression by altering IFN signaling, and high ATP1A1 expression levels were associated with poor postoperative survival in GC patients. The present results provide novel insights into the function of ATP1A1 as a mediator and/or biomarker of GC.
Source: Gastric Cancer - October 11, 2021 Category: Gastroenterology Source Type: research
LRRC8A influences the growth of gastric cancer cells via the p53 signaling pathway
ConclusionsThe present results indicate that LRRC8A functions as a mediator of and/or biomarker for GC.
Source: Gastric Cancer - August 5, 2021 Category: Gastroenterology Source Type: research
The expression of the alpha1 subunit of Na+/K+-ATPase is related to tumor development and clinical outcomes in gastric cancer
ConclusionsATP1A1 appears to regulate tumor progression by altering IFN signaling, and high ATP1A1 expression levels were associated with poor postoperative survival in GC patients. The present results provide novel insights into the function of ATP1A1 as a mediator and/or biomarker of GC.
Source: Gastric Cancer - July 12, 2021 Category: Gastroenterology Source Type: research
LRRC8A influences the growth of gastric cancer cells via the p53 signaling pathway
ConclusionsThe present results indicate that LRRC8A functions as a mediator of and/or biomarker for GC.
Source: Gastric Cancer - April 16, 2021 Category: Gastroenterology Source Type: research
Blockage of ETS homologous factor inhibits the proliferation and invasion of gastric cancer cells through the c-Met pathway
CONCLUSION: These results suggest that EHF plays a key role in cell proliferation, invasion, apoptosis, the cell cycle and EMT via the c-Met pathway. Therefore, EHF may serve as an antineoplastic target for the diagnosis and treatment of GC.PMID:33384550 | PMC:PMC7754554 | DOI:10.3748/wjg.v26.i47.7497
Source: World Journal of Gastroenterology - January 1, 2021 Category: Gastroenterology Authors: Meng-Li Gu Xin-Xin Zhou Meng-Ting Ren Ke-Da Shi Mo-Sang Yu Wen-Rui Jiao Ya-Mei Wang Wei-Xiang Zhong Feng Ji Source Type: research
Blockage of ETS homologous factor inhibits the proliferation and invasion of gastric cancer cells through the c-Met pathway.
CONCLUSION: These results suggest that EHF plays a key role in cell proliferation, invasion, apoptosis, the cell cycle and EMT via the c-Met pathway. Therefore, EHF may serve as an antineoplastic target for the diagnosis and treatment of GC.
PMID: 33384550 [PubMed - in process]
Source: World Journal of Gastroenterology - December 21, 2020 Category: Gastroenterology Authors: Gu ML, Zhou XX, Ren MT, Shi KD, Yu MS, Jiao WR, Wang YM, Zhong WX, Ji F Tags: World J Gastroenterol Source Type: research
Phosphoproteomic analysis identifies CLK1 as a novel therapeutic target in gastric cancer
ConclusionsOur data indicates that CLK1 plays a crucial role in the regulation of splicing process in gastric cancer and that CLK1 can act as a novel therapeutic target in gastric cancer.
Source: Gastric Cancer - August 20, 2020 Category: Gastroenterology Source Type: research
Inhibition of EZH2 and activation of ERR γ synergistically suppresses gastric cancer by inhibiting FOXM1 signaling pathway
ConclusionThe FOXM1 signaling pathway underlying the ERR γ-mediated gastric cancer suppression was identified. Furthermore, combined treatment with EZH2 inhibitor and ERRγ agonist synergistically suppressed GC progression by inhibiting this signaling pathway, suggesting its high potential in treating GC patients.
Source: Gastric Cancer - June 10, 2020 Category: Gastroenterology Source Type: research
Value of long non-coding RNA Rpph1 in esophageal cancer and its effect on cancer cell sensitivity to radiotherapy.
CONCLUSION: Rpph1 is highly expressed in esophageal cancer. Silencing Rpph1 expression can promote cell apoptosis, inhibit cell proliferation and migration, and increase radio-sensitivity.
PMID: 32351293 [PubMed - in process]
Source: World Journal of Gastroenterology : WJG - April 20, 2020 Category: Gastroenterology Authors: Li ZY, Li HF, Zhang YY, Zhang XL, Wang B, Liu JT Tags: World J Gastroenterol Source Type: research
