Inhibition of EZH2 and activation of ERR γ synergistically suppresses gastric cancer by inhibiting FOXM1 signaling pathway

ConclusionThe FOXM1 signaling pathway underlying the ERR γ-mediated gastric cancer suppression was identified. Furthermore, combined treatment with EZH2 inhibitor and ERRγ agonist synergistically suppressed GC progression by inhibiting this signaling pathway, suggesting its high potential in treating GC patients.
Source: Gastric Cancer - Category: Gastroenterology Source Type: research