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Total 66181 results found since Jan 2013.

Risk Stratification in a Tertiary Care Spine Centre: Comparison Between STarTBack and OSPRO-YF Screening Tools
CONCLUSIONS: STarTBack and OSPRO-YF are short screening tools with acceptable convergent and known-group construct validity and no floor or ceiling effect of their total score. Both tools could assist with the identification, evaluation, and management of psychological distress in patients presenting to tertiary care spine centres.PMID:37736380 | PMC:PMC10510560 | DOI:10.3138/ptc-2021-0026
Source: Physiotherapy Canada - September 22, 2023 Category: Physiotherapy Authors: Susan Robarts Helen Razmjou Albert Yee Joel Finkelstein Source Type: research

Gender-specific results of the Dresden children and adolescents headache program DreKiP
We examined gender differences in the outpatient multimodal Dresden Child and Adolescent Headache Program DreKiP.METHODS: We treated 140 patients with primary headache in a 15-hour structured group program. At baseline (T0) and six (T1) and twelve months (T2) after the end of the program, data on headache-related limitation of daily activities (PedMIDAS) as well as headache frequency, intensity, and pain-related disability (P-PDI) were collected. Retrospectively, these data were analyzed separately for girls and boys.RESULTS: For 91 patients (9-19 years, median = 15; 71.4 % female) data were available for at least two meas...
Source: Schmerz - September 22, 2023 Category: Anesthesiology Authors: Laura Zaranek Hanna Sobe Matthias Richter Anke H übler Reinhard Berner Maja von der Hagen Thea Koch Rainer Sabatowski Anna Klimova Gudrun Go ßrau Source Type: research

Are Social Deprivation and Low Traditional Health Literacy Associated With Higher PROMIS CAT Completion in Orthopaedic Surgery?
CONCLUSION: Within an urban, socioeconomically diverse, orthopaedic patient population, health literacy was associated with PROMIS CAT questionnaire completion. Lower health literacy levels increased the likelihood of not completing any part of the assigned PROMIS CAT questionnaires. Additionally, patients completed PROMIS CAT without fully understanding the questions. This indicates that patient completion does not guarantee comprehension of the questions nor validity of their scores, even more so among patients with low health literacy. This is a substantive concern for fidelity of data gathered from PROMIS CAT.CLINICAL ...
Source: Clinical Orthopaedics and Related Research - September 21, 2023 Category: Orthopaedics Authors: Audrey L Litvak Nicholas A Lin Kelly K Hynes Jason A Strelzow Megan A Conti Mica Jeffrey G Stepan Source Type: research

Nutrition-associated health levels in persons with cancer: item response modelling based on the International Classification of Functioning, Disability and Health
CONCLUSIONS: The study constructed an evidence-based ICF scale for nutrition conditions in patients with cancer with 32-item and 2PLM for evaluating nutrition-associated health level in persons with cancer, including high validity and reliability.CLINICAL REHABILITATION IMPACT: The IRT model based on ICF provided a promising assessment tool to discriminate nutrition-associated health level of persons with cancer, and offered an auxiliary method for selecting rehabilitation intervention targets. This has the potential to lead to improved outcomes in cancer treatment and increased quality of life for cancer survivors.PMID:37...
Source: Methods of Information in Medicine - September 21, 2023 Category: Information Technology Authors: Jin-Jin Chen Zi-Yan Zhu Jia-Jia Bian Feng Lin Source Type: research

Current practice of outpatient rehabilitation services in patients with mobility-impaired paralysis due to stroke or spinal cord injury: a qualitative interview study in Germany
CONCLUSION: Areas of improvement identified focused on: setting rehabilitation goals towards participation, training therapists on evidence-based treatments and shared decision-making, updating the outpatient service catalogue, and implementing coordination actions. Implementation of these recommendations should be evaluated.PMID:37732606 | DOI:10.1080/09638288.2023.2259301
Source: Disability and Rehabilitation - September 21, 2023 Category: Rehabilitation Authors: Tiziana Daniel Tamara Spingler Andreas Hug Norbert Weidner Michel Wensing Charlotte Ullrich Source Type: research

The experience of falls and fall risk during the subacute phase of spinal cord injury: a mixed methods study
Conclusions: The findings highlight the need for fall prevention initiatives during subacute SCI, when individuals are learning to manage their increased fall risk.PMID:37732508 | DOI:10.1080/09638288.2023.2259311
Source: Disability and Rehabilitation - September 21, 2023 Category: Rehabilitation Authors: Olinda Habib Perez Katherine Chan Samantha Martin Andresa Marinho-Buzelli Hardeep Singh Kristin E Musselman Source Type: research

A cross-sectional study of multidimensional fatigue in biologic-treated rheumatoid arthritis: which variables play a role?
CONCLUSIONS: Our findings indicate that effectively addressing fatigue in RA patients requires an individualized approach. This approach should acknowledge the varying degrees of fatigue across different fatigue dimensions (physical or mental), while also taking into account the patient's mental health problems, pain levels, and disability levels.PMID:37731384 | DOI:10.1080/09638288.2023.2258333
Source: Disability and Rehabilitation - September 21, 2023 Category: Rehabilitation Authors: Alexandra Husivargova Vladimira Timkova Zelmira Macejova Zuzana Kotradyova Robbert Sanderman Joke Fleer Iveta Nagyova Source Type: research

Quality of life following non-dysvascular lower limb amputation is contextualized through occupations: a qualitative study
CONCLUSION: The findings from this work can be leveraged by clinicians and researchers alike to improve care for this population. Rehabilitation programs should consider interventions and programming that help to restore occupations or develop new ones given the importance placed on occupations by persons with non-dysvascular LLA.PMID:37731381 | DOI:10.1080/09638288.2023.2258340
Source: Disability and Rehabilitation - September 21, 2023 Category: Rehabilitation Authors: Stephanie R Cimino Sander L Hitzig Vera Fung Katie N Dainty Crystal MacKay Joanna E M Sale Amanda L Mayo Sara J T Guilcher Source Type: research

Novel insight into the phenotype of microcephaly 19 in the patient with missense COPB2 mutation
This study describes a missense pathogenic homozygous variant (NM_004766.3:c.760 C > T, p.Arg254Cys) in the COPB2 gene, which was identified by Whole-Exome sequencing and confirmed by Sanger sequencing. The proband of the present study is an eight-and-a-half-year-old Iranian female who was born to consanguineous parents. She manifests global developmental delay, intellectual disability, microcephaly, seizures, spasticity, strabismus, and failure to thrive symptoms. Moreover, she is unable to stand, walk, or speak. Here we report the second homozygous mutation (NM_004766.3:c.760 C > T, p.Arg254Cys) in the COPB2 gene i...
Source: European Journal of Medical Genetics - September 21, 2023 Category: Genetics & Stem Cells Authors: Amirmasoud Shiri Hossein Jafari Khamirani Neda Kamal Jamal Manoochehri Mehdi Dianatpour Seyed Mohammad Bagher Tabei Seyed Alireza Dastgheib Source Type: research

A CAMK2B variant associated with tetralogy of Fallot, developmental delay, and growth retardation
Eur J Med Genet. 2023 Sep 19:104845. doi: 10.1016/j.ejmg.2023.104845. Online ahead of print.ABSTRACTCAMK2B encodes the beta-subunit of calcium/calmodulin-dependent protein kinase II (CAMKII), which is expressed mainly in the brain. Variants of CAMK2A and CAMK2B cause neurodevelopmental disorders, and CAMK2B alterations have been described in at least 14 patients with intellectual disability and developmental delay. Here, we describe a novel CAMK2B variant in a patient with tetralogy of Fallot (TOF), developmental delay, and growth retardation. The patient was a 2-year-old female. She was delivered at 36 weeks 6 days gestat...
Source: European Journal of Medical Genetics - September 21, 2023 Category: Genetics & Stem Cells Authors: Yuji Horii Yukiko Kuroda Yoko Saito Yumi Enomoto Takuya Naruto Kenji Kurosawa Source Type: research

A novel < em > METTL5 < /em > variant disrupting a donor splice site leads to primary microcephaly-related intellectual disability in an Iranian family: clinical features and literature review
In this study, due to the genetic heterogeneity of the disease, the whole-exome sequencing (WES) was performed on a 13-year-old boy suffering from microcephaly. In addition, Sanger sequencing, cosegregation analysis, and structural modelling were performed to identify and verify the causative variant in the proband and obligate carriers in the family. WES revealed a novel, homozygote 10-bp deletion in the donor splice site of 2nd exon of METTL5 gene (NM_014168:c.223_224?8del), which was found segregating with the phenotype in the pedigree. This variant meets the criteria of being pathogenic according to the American Colleg...
Source: Journal of Genetics - September 21, 2023 Category: Genetics & Stem Cells Authors: Fatemeh Shakarami Zahra Nouri Hossein Khanahmad Mohamadreza Ghazavi Mohammad Amin Tabatabaiefar Source Type: research

Motivation-related influences on fNIRS signals during walking exercise: a permutation entropy approach
This study provides early evidence to suggest that while different motivational environments during walking activity influence the magnitude of fNIRS signals, they may not influence the regularity of cortical signals. However, the magnitude of PE difference between motivational conditions was related to self-determined motivation in the aPFC, and this is an area warranting further investigation.PMID:37733031 | DOI:10.1007/s00221-023-06707-5
Source: Brain Research - September 21, 2023 Category: Neurology Authors: Sarah M Schwab Dalton Cooper Nicole S Carver Sarah Doren Pierce Boyne Source Type: research

Understanding wheelchair use in older adults from the National Health and Aging Trends Study
CONCLUSIONS: Current wheelchair users reported more physical difficulties and were much less likely to go outside. This lower outdoor mobility could be due to physical difficulties or potential barriers in physical and socio-cultural environments. In addition, older adults who do not use wheelchairs showed increasing physical problems over time (including balance or coordination problems). Clinicians should consider older wheelchair users' health and physical limitations when prescribing wheelchairs.PMID:37734645 | DOI:10.1016/j.apmr.2023.09.006
Source: Health Physics - September 21, 2023 Category: Physics Authors: Qiong Nie Laura A Rice Jacob J Sosnoff Sa Shen Wendy A Rogers Source Type: research

Nutrition-associated health levels in persons with cancer: item response modelling based on the International Classification of Functioning, Disability and Health
CONCLUSIONS: The study constructed an evidence-based ICF scale for nutrition conditions in patients with cancer with 32-item and 2PLM for evaluating nutrition-associated health level in persons with cancer, including high validity and reliability.CLINICAL REHABILITATION IMPACT: The IRT model based on ICF provided a promising assessment tool to discriminate nutrition-associated health level of persons with cancer, and offered an auxiliary method for selecting rehabilitation intervention targets. This has the potential to lead to improved outcomes in cancer treatment and increased quality of life for cancer survivors.PMID:37...
Source: Health Physics - September 21, 2023 Category: Physics Authors: Jin-Jin Chen Zi-Yan Zhu Jia-Jia Bian Feng Lin Source Type: research