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Microneedle-Based Vaccine Delivery: Review of an Emerging Technology
AAPS PharmSciTech. 2022 Apr 5;23(4):103. doi: 10.1208/s12249-022-02250-8.ABSTRACTVaccination has produced a great improvement to the global health by decreasing/eradicating many infectious diseases responsible for significant morbidity and mortality. Thanks to vaccines, many infections affecting childhood have been greatly decreased or even eradicated (smallpox, measles, and polio). That is why great efforts are made to achieve mass vaccination against COVID-19. However, developed vaccines face many challenges with regard to their safety and stability. Moreover, needle phobia could prevent a significant proportion of the p...
Source: AAPS PharmSciTech - April 6, 2022 Category: Drugs & Pharmacology Authors: Ihab Mansoor Heba A Eassa Kamilia H A Mohammed Marwa A Abd El-Fattah Marwa H Abdo Eman Rashad Hadeer A Eassa Asmaa Saleh Omnya M Amin Mohamed Ismail Nounou Ola Ghoneim Source Type: research

Evaluation of the Safety and Immunogenicity of M-M-RII (Combination Measles-mumps-rubella Vaccine): Clinical Trials of Healthy Children and Adults Published Between 2010 and 2019
Conclusions: In trials published from 2010 to 2019, M-M-RII continued to be safe and immunogenic in all age groups studied. These data, along with the results of earlier trials, indicate that the performance of the vaccine has been consistent across more than 30 years of postlicensure studies.
Source: The Pediatric Infectious Disease Journal - October 19, 2021 Category: Infectious Diseases Tags: Vaccine Reports Source Type: research

Adverse events following immunization: Findings from 2017/2018 measles vaccination campaign, Nigeria AEFI reporting in 2017/2018 measles vaccination campaign
CONCLUSION: Adequate AEFI reporting, Investigation and management remains important in managing the risk of a disruption of mass campaigns. The deployment of supervisors during campaign may play an important role in improving the identification and reporting of suspected AEFI. Further inquiries about AEFIs during the post campaign coverage evaluation also played a role in improving AEFI reporting and documentation. The real-time, on the spot, follow up by the national operations team helped with decision making and intervention including AEFI investigations and assessments.PMID:33714655 | DOI:10.1016/j.vaccine.2021.02.067
Source: Vaccine - March 14, 2021 Category: Allergy & Immunology Authors: Ene Gbenewei Terna Nomhwange Lydia Taiwo Isiaka Ayodeji Kabir Yusuf Anne E Jean Baptiste Peter Nsubuga Fiona Braka Joseph Oteri Faisal Shuaib Source Type: research

The Ambulance Science Podcast: Make Up Your Own Mind About the Vaccine
Get every episode of The Ambulance Science Podcast by subscribing to Apple Podcasts or Google Podcasts. Where I’m coming from (compared to most of my colleagues): Master’s in Public Health with a concentration in Health Policy from Yale Medical School.FT Faculty at GWU School of Medicine & Southern Connecticut State University MPH Program, and long-time adjunct faculty at NYMC MPH program in Health Policy.Assistant Commissioner of Health at the NYC Department of Health & Mental Hygiene during the first SARS outbreak.Served as State EMS Director, Consultant to Public Health ...
Source: JEMS Special Topics - December 14, 2020 Category: Emergency Medicine Authors: JEMS Staff Tags: Podcasts Ambulance Science Source Type: news

21st century outbreaks
  Which diseases have generated the highest number of cases from outbreaks during the first two decades of the 21st century?  In this blog, we can use GIDEON’s data to find out. ‘Disease outbreak’ is a scary term for many, but every year we suffer dozens, if not hundreds, of localized and international disease outbreaks across the world. While these outbreaks are always significant to those affected, they rarely generate headlines,  and can sometimes go unnoticed outside of the Healthcare Industry. An “outbreak” is often defined as an increase in case numbers for a particular disease in a defined place and...
Source: GIDEON blog - December 3, 2020 Category: Databases & Libraries Authors: Kristina Symes Tags: Epidemiology News Outbreaks Source Type: blogs

Top 10 most prominent diseases of the 21st Century
Which diseases have generated the highest number of cases from outbreaks during the first two decades of the 21st century?  In this blog, we can use GIDEON’s data to find out. ‘Disease outbreak’ is a scary term for many, but every year we suffer dozens, if not hundreds, of localized and international disease outbreaks across the world. While these outbreaks are always significant to those affected, they rarely generate headlines,  and can sometimes go unnoticed outside of the Healthcare Industry. An “outbreak” is often defined as an increase in case numbers for a particular disease in a defined place and time. ...
Source: GIDEON blog - December 1, 2020 Category: Databases & Libraries Authors: Kristina Symes Tags: Epidemiology News Outbreaks Source Type: blogs

The Three Groups of People Biden Must Reach Out to if He Wants to End the Pandemic, According to Dr. Leana Wen
When the long history of the COVID-19 pandemic is finally written, Dr. Leana Wen will be remembered as one of the most reassuring faces and reliable voices in this period of hardship. A former health commissioner of Baltimore and current visiting professor at the George Washington University School of Public Health, Wen has provided both encouragement and tough-love truths for a public hungry for information and counsel. In a Nov. 19 conversation with TIME’s Alice Park, she offered her candid thoughts about what is very much an inflection point in the pandemic—with two new vaccines (one from Moderna and one fro...
Source: TIME: Health - November 19, 2020 Category: Consumer Health News Authors: Jeffrey Kluger Tags: Uncategorized COVID-19 Source Type: news

The False Choice Between Science And Economics
This article originally appeared on The Bulwark here. The post The False Choice Between Science And Economics appeared first on The Health Care Blog.
Source: The Health Care Blog - May 1, 2020 Category: Consumer Health News Authors: Christina Liu Tags: COVID-19 Health Policy David Shaywitz Source Type: blogs

Vaccines, Antibodies and Drug Libraries. The Possible COVID-19 Treatments Researchers Are Excited About
In early April, about four months after a new, highly infectious coronavirus was first identified in China, an international group of scientists reported encouraging results from a study of an experimental drug for treating the viral disease known as COVID-19. It was a small study, reported in the New England Journal of Medicine, but showed that remdesivir, an unapproved drug that was originally developed to fight Ebola, helped 68% of patients with severe breathing problems due to COVID-19 to improve; 60% of those who relied on a ventilator to breathe and took the drug were able to wean themselves off the machines after 18...
Source: TIME: Health - April 14, 2020 Category: Consumer Health News Authors: Alice Park Tags: Uncategorized COVID-19 Source Type: news

What Infectious Diseases are Important to Consider in Transplantation Patients?
Discussion Transplantation is not a common problem for primary care physicians but when a child’s disease has progressed to end-stage organ failure, transplantation can be the only treatment available. While the primary care provider usually is not involved in the daily management of patients before, during and after transplantation, they can be involved in many areas. These can include providing appropriate primary and acute care, ordering and obtaining necessary medical tests, medications and equipment, assisting with medical insurance, providing medical history and records to consultants, translating medical infor...
Source: PediatricEducation.org - June 24, 2019 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

Measles Vaccine, Acute Appendicitis, Screening for Heart Disease, Abdominal Pain, Hyperhidrosis.
Authors: PMID: 31150185 [PubMed - in process]
Source: American Family Physician - May 31, 2019 Category: Primary Care Tags: Am Fam Physician Source Type: research

Why the measles outbreak has roots in today's political polarization
♪ Seizing our newborn infants,Blighting their lives with pain;Filling their veins with poison,Tainting each tender brain ♫So go the lyrics of theAnti-Compulsory Vaccination Hymn, circulated not by the modern-day anti-vaccine bandthe Refusers but by the Anti-Vaccination Society of America....
Source: Los Angeles Times - Science - May 9, 2019 Category: Science Authors: Emily Baumgaertner Source Type: news

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