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Infectious Disease: Tuberculosis
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Total 2919 results found since Jan 2013.
A Very Unusual Presentation of Miliary Tuberculosis and Osteomyelitis as an Incidental Finding of Musculoskeletal Pain
Cureus. 2023 Aug 27;15(8):e44207. doi: 10.7759/cureus.44207. eCollection 2023 Aug.ABSTRACTTuberculosis (TB) is a highly infectious disease that takes the primary or latent route. In primary TB, the patient often presents with constitutional symptoms such as cough, fever, weight loss, and hemoptysis. This 83-year-old patient was sent to the emergency department (ED) by her primary care physician after abnormal imaging for acute back and neck pain. Imaging revealed pulmonary TB with possible tuberculosis osteomyelitis versus metastatic carcinoma to the cervical vertebrae. The case's unique presentation gives light to the nee...
Source: Pain Physician - September 18, 2023 Category: Anesthesiology Authors: Prachi B Patel Bhavi Purohit Source Type: research
Retrospective Evaluation of Short-Course versus Traditional Preoperative Chemotherapy in Thoracolumbar Spinal Tuberculosis Patients
CONCLUSIONS For patients suffering from thoracolumbar spinal tuberculosis exhibiting progressive neurological deterioration, surgical intervention is deemed feasible after a brief period (usually 1-7 days) of intensive preoperative antitubercular therapy. This finding suggests that short-course intensive preoperative chemotherapy may serve as a viable approach in managing such cases.PMID:37697647 | DOI:10.12659/MSM.941003
Source: Medical Science Monitor - September 12, 2023 Category: Research Authors: Lin Chen Jun Zhang Source Type: research
Tuberculosis prevalence after 4 years of population-wide systematic TB symptom screening and universal testing and treatment for HIV in the HPTN 071 (PopART) community-randomised trial in Zambia and South Africa: A cross-sectional survey (TREATS)
ConclusionsThere was no evidence that the PopART intervention reduced TB prevalence. Systematic screening for TB that is based on symptom screening alone may not be sufficient to achieve a large reduction in TB prevalence over a period of several years. Including chest X-ray screening alongside TB symptom screening could substantially increase the sensitivity of systematic screening for TB. Trial registrationThe TREATS study was registered with ClinicalTrials.gov Identifier: NCT03739736 on November 14, 2018. The HPTN 071 (PopART) trial was registered at ClinicalTrials.gov under number NCT01900977 on July 17, 2013.
Source: PLoS Medicine - September 8, 2023 Category: Internal Medicine Authors: Eveline Klinkenberg Source Type: research
Unveiling foot tuberculosis as an under-recognized source of foot pain
ConclusionFoot tuberculosis presents with nonspecific symptoms, leading to misdiagnosis and delays in appropriate treatment. Clinical examination, radiographic evaluation, and biopsy are essential for accurate diagnosis. Early initiation of ATT is crucial for favourable outcomes. Factors such as high initial ESR, delayed treatment initiation, multiple lesions, and tarsal involvement negatively impact prognosis. This study highlights the importance of recognizing foot tuberculosis and provides insights into its clinical presentation, radiographic features, and treatment outcomes, facilitating timely intervention and improve...
Source: International Orthopaedics - September 5, 2023 Category: Orthopaedics Source Type: research
Total hip arthroplasty in active and advanced tubercular arthritis: a systematic review of the current evidence
ConclusionTHA is a safe and effective surgical intervention in patients with active and advanced TB arthritis of hip. It is recommended that the surgery be performed under cover of multi-drug anti-tubercular regimen. In patients with active sinus tracts, abscesses and TIS, surgery may be accomplished in a multi-staged manner. The clinical (range of motion, deformity correction, walking ability and pain scores), radiological (evidence of radiological reactivation and implant incorporation) and function outcome (as assessed by HHS) significantly improve after THA in these patients.
Source: International Orthopaedics - September 5, 2023 Category: Orthopaedics Source Type: research
Pulmonary alveolar microlithiasis: a rare case report from Syria
CONCLUSIONS: The disease progresses slowly and is often diagnosed incidentally. Lung transplantation remains the only effective treatment.PMID:37663718 | PMC:PMC10473359 | DOI:10.1097/MS9.0000000000001060
Source: Annals of Medicine - September 4, 2023 Category: Internal Medicine Authors: Duaa Batesh Roaa Habash Mhd Nabih Alhaffar Imad Almani Source Type: research
Orchids of Dibru-Saikhowa: A Systematic Review on Their Traditional Use, Pharmacological Activity and Phytochemistry
CONCLUSION: Orchids found in DSNPBR hold great significance in traditional culture for their medicinal properties and have been effectively studied for their bioactivities. Nevertheless, to confirm their effectiveness as therapeutics, conducting methodical research, examining their molecular mechanisms, and performing toxicity tests are necessary.PMID:37649298 | DOI:10.2174/1568026623666230830125205
Source: Current Topics in Medicinal Chemistry - August 31, 2023 Category: Chemistry Authors: Pal Gogoi Saikat Sen Source Type: research
