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Total 570 results found since Jan 2013.

Omega-3 polyunsaturated fatty acids and the psychiatric post-acute sequelae of COVID-19: A one-year retrospective cohort analysis of 33,908 patients
CONCLUSION: Omega-3 PUFAs may require re-evaluation as a preventive strategy against adverse mental health outcomes post-COVID-19 in placebo-controlled clinical trials.PMID:37716377 | DOI:10.1016/j.bbi.2023.09.008
Source: Brain, Behavior, and Immunity - September 16, 2023 Category: Neurology Authors: Ting-Hui Liu Chung-Han Ho Daniel Tzu-Li Chen Jheng-Yan Wu Po-Yu Huang Chih-Cheng Lai Kuang-Yang Hsieh Kuan-Pin Su Source Type: research

Clinical phenotypes and quality of life to define post-COVID-19 syndrome: a cluster analysis of the multinational, prospective ORCHESTRA cohort
EClinicalMedicine. 2023 Jul 21;62:102107. doi: 10.1016/j.eclinm.2023.102107. eCollection 2023 Aug.ABSTRACTBACKGROUND: Lack of specific definitions of clinical characteristics, disease severity, and risk and preventive factors of post-COVID-19 syndrome (PCS) severely impacts research and discovery of new preventive and therapeutics drugs.METHODS: This prospective multicenter cohort study was conducted from February 2020 to June 2022 in 5 countries, enrolling SARS-CoV-2 out- and in-patients followed at 3-, 6-, and 12-month from diagnosis, with assessment of clinical and biochemical features, antibody (Ab) response, Variant o...
Source: Cell Research - September 1, 2023 Category: Cytology Authors: Elisa Gentilotti Anna G órska Adriana Tami Roy Gusinow Massimo Mirandola Jes ús Rodríguez Baño Zaira R Palacios Baena Elisa Rossi Jan Hasenauer Iris Lopes-Rafegas Elda Righi Natascia Caroccia Salvatore Cataudella Zeno Pasquini Thomas Osmo Lidia Del Pi Source Type: research

Controversies in Dental Traumatology
The management of traumatic dental injuries is more a shade of gray than it is black and white because not all treatment procedures used for dental trauma management are fully evidence based. This chapter has highlighted some of the gray areas related to the treatment and outcome of traumatic dental injuries. Significant controversies in the management of luxation and avulsive injuries have been brought out. Adjunctive treatment such as antibiotic usage, tetanus vaccination, and pain management is also addressed.
Source: Dental Clinics of North America - August 30, 2023 Category: Dentistry Authors: Orrett E. Ogle Source Type: research

COVID-19 Vaccine –Associated Myocarditis Considerations for Competitive Athletes
AbstractPurpose of reviewTo review the epidemiology of COVID-19 vaccine –associated myocarditis (VAM), evaluation of athletes with suspected VAM, and safe return to play for athletes with confirmed VAM.Recent findingsVAM is a rare complication of COVID-19 vaccination, with pretest probability highest in those who experience chest pain within several days after messenger RNA vaccine administration. While data from young athletes with VAM are lacking, the initial evaluation for those with high pre-test probability of  VAM includes ECG, echocardiography, and troponin testing. Those with abnormal testing warrant cardiac mag...
Source: Current Treatment Options in Cardiovascular Medicine - August 26, 2023 Category: Cardiology Source Type: research

Experience of Lifetime Health Maintenance Program: An Observational Study of a 30-Year Period of Outpatient Primary Care in a Tertiary Hospital
CONCLUSION: The LHMP emphasized the need to systematize regular primary care physicians in Korea. Policy changes are necessary to strengthen primary care, and the LHMP serves as an intermediate step in organizing regular primary care physicians in Korea.PMID:37582665 | DOI:10.4082/kjfm.23.0023
Source: Pain Physician - August 15, 2023 Category: Anesthesiology Authors: Seo Young Kang Young Sik Kim Source Type: research

Pulmonary Arterial Hypertension: Unraveling Its Impact On Heart And Lungs
Conclusion Navigating the complexities of Pulmonary Arterial Hypertension (PAH) might seem daunting. However, with the right knowledge and proactive approach, it’s possible to manage the condition and maintain a good quality of life. PAH, a unique type of high blood pressure affecting the arteries in the lungs, can put extra strain on the heart. Over time, this can lead to heart failure. The condition’s root cause may vary, from genetic factors to other health issues like heart defects, liver disease, or autoimmune diseases. Remember, sometimes the cause remains unknown, resulting in idiopathic pulmonary ...
Source: The EMT Spot - July 19, 2023 Category: Emergency Medicine Authors: Michael Rotman, MD, FRCPC, PhD Tags: Blood Pressure Source Type: blogs

Gastrointestinal tract and viral pathogens
World J Virol. 2023 Jun 25;12(3):136-150. doi: 10.5501/wjv.v12.i3.136.ABSTRACTViral gastroenteritis is the most common viral illness that affects the gastrointestinal (GI) tract, causing inflammation and irritation of the lining of the stomach and intestines. Common signs and symptoms associated with this condition include abdominal pain, diarrhea, and dehydration. The infections commonly involved in viral gastroenteritis are rotavirus, norovirus, and adenovirus, which spread through the fecal-oral and contact routes and cause non-bloody diarrhea. These infections can affect both immunocompetent and immunocompromised indiv...
Source: Herpes - July 3, 2023 Category: Infectious Diseases Authors: Gowthami Sai Kogilathota Jagirdhar Yashwitha Sai Pulakurthi Himaja Dutt Chigurupati Salim Surani Source Type: research

Post-Vaccine Era COVID-19 Pandemic-related Distress in Palliative Care Patients with Advanced Cancer
The COVID-19 pandemic represents a source of distress in patients with advanced cancer; however, few studies have examined the extent of pandemic-related distress in the post-vaccine era.
Source: Journal of Pain and Symptom Management - June 30, 2023 Category: Palliative Care Authors: Kaoswi K Shih, Adrienne B Arechiga, Xi Chen, Diana L. Urbauer, Aline Rozman De Moraes, Ashley J Rodriguez, Lisa Thomas, Penny A Stanton, Eduardo Bruera, David Hui Tags: Original Article Source Type: research

Non-pharmacological management of infant and young child procedural pain
CONCLUSIONS: Overall, non-nutritive sucking, facilitated tucking, and swaddling may reduce pain behaviours in preterm born neonates. Non-nutritive sucking may also reduce pain behaviours in full-term neonates. No interventions based on a substantial body of evidence showed promise in reducing pain behaviours in older infants. Most analyses were based on very low- or low-certainty grades of evidence and none were based on high-certainty evidence. Therefore, the lack of confidence in the evidence would require further research before we could draw a definitive conclusion.PMID:37314064 | DOI:10.1002/14651858.CD006275.pub4
Source: Cochrane Database of Systematic Reviews - June 14, 2023 Category: General Medicine Authors: Rebecca R Pillai Riddell Oana Bucsea Ilana Shiff Cheryl Chow Hannah G Gennis Shaylea Badovinac Miranda DiLorenzo-Klas Nicole M Racine Sara Ahola Kohut Diana Lisi Kara Turcotte Bonnie Stevens Lindsay S Uman Source Type: research

Top 100 Most-Cited Papers in Herpes Zoster from 2000 to 2022: A Bibliometric Study
CONCLUSION: In terms of the quantity of T100 articles, researchers, and organizations, the US is the predominant country. The most T100 papers were published in the special journal Clinical Infectious Diseases. The most academic focus remain the remedies for postherpetic neuralgia and vaccine development for individualized groups.PMID:37273270 | PMC:PMC10237222 | DOI:10.2147/JPR.S409616
Source: Herpes - June 5, 2023 Category: Infectious Diseases Authors: Ning Gao Meng Li Weiming Wang Lei Wang Zhen Liu Yufeng Guo Source Type: research

TREMFYA ® (guselkumab) Provides Sustained Improvements Across All Minimal Disease Activity Domains for Adults Living with Active Psoriatic Arthritis in Phase 3b Trial
SPRING HOUSE, PENNSYLVANIA, May 31, 2023 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced new data from the Phase 3b COSMOS clinical trial showing that treatment with TREMFYA® (guselkumab) provided sustainable improvements in all minimal disease activity (MDA)a domains through week 48 in adults living with active psoriatic arthritis (PsA) who previously had an inadequate response to one to two tumor necrosis factor inhibitors (TNFi-IR).[1] In a separate post-hoc analysis of the Phase 3 DISCOVER-1 and DISCOVER-2b clinical trial findings, TREMFYA was shown to be associated with prompt and su...
Source: Johnson and Johnson - May 31, 2023 Category: Pharmaceuticals Tags: Latest News Source Type: news