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Impact of metformin on statin ‐associated myopathy risks in dyslipidemia patients
This study found that a comedication with metformin was associated with decreased myopathy risk in statin-treated dyslipidemia patients compared to statin-only users. Our findings suggest that metformin may provide protective effects on potential muscle toxicities induced by statin therapy.
Source: Pharmacology Research and Perspectives - July 8, 2023 Category: Drugs & Pharmacology Authors: Keunhyeong Bak, Suhyeon Moon, Minjung Ko, Yeo Jin Choi, Sooyoung Shin Tags: ORIGINAL ARTICLE Source Type: research

Proton Pump Inhibitors Increase the Risk of Autoimmune Diseases: A Nationwide Cohort Study
ConclusionsOur retrospective population-based cohort study showed that the prescription of proton pump inhibitors is associated with a higher risk of ADs.
Source: Frontiers in Immunology - September 30, 2021 Category: Allergy & Immunology Source Type: research

Real-World Analyses of the Safety Outcome among a General Population Treated with Statins: An Asian Population-Based Study
CONCLUSIONS: Compared with atorvastatin and rosuvastatin, pitavastatin might be associated with a lower risk of safety events in Asians.PMID:34497171 | DOI:10.5551/jat.63076
Source: Journal of Atherosclerosis and Thrombosis - September 9, 2021 Category: Cardiology Authors: Jia-Ling Lin Po-Sheng Chen Hui-Wen Lin Liang-Miin Tsai Sheng-Hsiang Lin Yi-Heng Li Source Type: research

Temporal relationship between idiopathic inflammatory myopathies and malignancies and its mortality: a nationwide population-based study
ConclusionsAmong IIM patients with malignancy, common sites of malignancy were different between the CAM and CNAM groups, and patients with CAM had poor prognosis compared with CNAM patients.Key Points•The malignancies commonly occurred in incident idiopathic inflammatory myopathy (IIM) patients, especially within 1  year before and after the initial IIM diagnosis.•Patients with malignancy had poor survival compared with patients without malignancy.•Among the IIM patients with malignancy, patients who developed malignancy within 3  years of IIM diagnosis (cancer-associated myositis, or CAM, group) showed higher mor...
Source: Clinical Rheumatology - May 4, 2020 Category: Rheumatology Source Type: research

DPP-4 Inhibitors in Combination with Lipid-Lowering Agents and Risk of Serious Muscular Injury: A Nested Case-Control Study in a Nationwide Cohort of Patients with Type 2 Diabetes Mellitus
ConclusionIn this study, DPP-4 inhibitor use was not associated with an increased risk of serious muscular injury among patients with type 2 diabetes mellitus using statins or fibrates.
Source: Drug Safety - April 17, 2020 Category: Drugs & Pharmacology Source Type: research

Efficacy and Safety of High-intensity Statins in Patients with Acute Myocardial Infarction: An Asian Perspective
ConclusionsAMI patients in Taiwan with HIS had similar clinical outcomes to those with non-HIS. Using HIS for effective reduction of low-density lipoprotein cholesterol is safe in Taiwan.
Source: Canadian Journal of Cardiology - November 2, 2019 Category: Cardiology Source Type: research

Prevalence and Socioeconomic Status of Patients with Genetic Myopathy in Korea: A Nationwide, Population-Based Study
Conclusions: Our study was the first nationwide epidemiologic study of the prevalence and socioeconomic status of patients with genetic myopathy in Korea. Our results confirmed a sex divergence in a younger population and those with low socioeconomic status among patients with genetic myopathy.Neuroepidemiology
Source: Neuroepidemiology - June 14, 2019 Category: Epidemiology Source Type: research

Statin ‐associated myopathy. Assessment of frequency based on data of all statutory health insurance funds in Germany
Pharmacology Research&Perspectives,Volume 6, Issue 3, June 2018.
Source: Pharmacology Research and Perspectives - May 10, 2018 Category: Drugs & Pharmacology Authors: Peter Ihle , Franz ‐Werner Dippel , Ingrid Schubert Source Type: research

10-year trends in statin utilization in Taiwan: a retrospective study using Taiwans National Health Insurance Research Database
Conclusion Atorvastatin was the most commonly used statin in Taiwan during 2002–2011. While patients with history of CVD were more likely to be prescribed higher intensity statins compared with those without, this difference was not found comparing those with and without diabetes.
Source: BMJ Open - May 17, 2017 Category: General Medicine Authors: Hsieh, H.-C., Hsu, J. C., Lu, C. Y. Tags: Open access, Evidence based practice Research Source Type: research

Epidemiology of idiopathic inflammatory myopathy in Hungary.
CONCLUSIONS: The authors propose to establish a National Myositis Registry in the frame of multicentric collaboration in order to have more information about the disease. Orv. Hetil., 2014, 155(41), 1643-1646. PMID: 25282109 [PubMed - in process]
Source: Orvosi Hetilap - October 1, 2014 Category: Journals (General) Authors: Nagy-Vincze M, Bodoki L, Griger Z, Dankó K Tags: Orv Hetil Source Type: research